30 Years Old, missing one ovary, endometriosis and severe menopausal symptoms.

by Krystina
(Grosse Pointe MI)

Hi. I am 30 years old, I have suffered with severe endometriosis for over 14 years, I have had 3 surgeries and as of last year had an ovary and tube removed due to a large cyst that was pre canerous. Prior to surgery I began having hot flashes, night sweats, irregular heavy periods, decreased sex drive and insomnia, I also have severe pms. My cycle ranges anywhere from 15-23 days, and I have tried other methods of control, and I am unable to tolerate hormone treatment as I have migraines. I am hoping to find some natral relief with this treatment, my symptoms have been worse since the removal of the ovary and I am just hoping to feel "normal" again. I ordered the cream and I am wating as patiently as possible. I appreciate any words of encouragment and advice.

Anticipating a Miracle!!

Grosse Pointe MI

Comments for 30 Years Old, missing one ovary, endometriosis and severe menopausal symptoms.

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Feb 03, 2012
30 Years Old, missing one ovary, endometriosis and severe menopausal symptoms
by: Wray

Hi Krystina Well I can't guarantee a miracle, but I have found progesterone can help! Endo is caused by oxidative stress, so large amounts of anti-oxidants are needed. See this page here for a list of them. Excess oestrogen exacerbates symptoms, as it's not only an inflammatory hormone, but a mitogen too. This causes the endo cells to multiply and divide, compounding the problem. It's evident you have excess from the symptoms you describe. Not knowing your medical history, it appears you were either not ovulating, or if you were, the corpus luteum was making insufficient progesterone to counter the oestrogen. Was this ever checked?! These are a few papers on a defective luteal phase, see here, here and here. Unfortunately high oestrogen upsets the cycle, suppressing progesterone further. Ovulation alternates between the two ovaries, see here. Pure speculation on my part, but possibly the ovary that was removed was the only one ovulating. Or the ovaries are still alternating, but with one missing, you are getting even less progesterone, hence a worsening of symptoms. Interesting you are unable to tolerate hormone treatment, I take it by this you mean Contraceptives? All drug based contraceptives have the potential to harm, plus they stop the ovarian cycle, reducing progesterone. You might like to see this page here. Scroll to the bottom to find the reference. Progesterone does help migraines, see here, here, here, here, here and here. Normally I recommend 100-200mg/day, but with severe endo I've found 500mg/day or more is needed. Continued below.

Feb 03, 2012
30 Years Old, missing one ovary, endometriosis and severe menopausal symptoms Part 2
by: Wray

Hi Krystina We do have a page on Endometriosis with more info. Hot flushes usually respond to levels of 400mg/day and over. So I would strongly advise using a very high amount, as I've found too low worsens symptoms. There's more info about this on our page Oestrogen Dominance. Have they ever checked your SHBG and testosterone levels? If SHBG is too low, free testosterone rises, this can cause severe PMS, progesterone does increase SHBG, thus lowering testosterone, see here. The amounts used in the study were very high, but they used oral progesterone which is not the best Delivery system. Please avoid all sugars, and sweet starchy foods, ie all grains, legumes and fruits or veggies which fall into this category. For two reasons, sugars of any kind are the most oxidising substances that we eat, ie free radicals abound and cause inflammation, and they decrease SHBG. This leads to higher testosterone and oestrogen. Please have a vitamin D test done, it's the most vital antioxidant, and low in most of us. For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Continued below.

Feb 03, 2012
30 Years Old, missing one ovary, endometriosis and severe menopausal symptoms Part 3
by: Wray

Hi Krystina You might like to read these comments from users of high amounts, see here, here, here, here, here, here and here. Take care Wray

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