Spironolactone Causing Severe Shoulder Pain & Neuropathy in Feet? Help! What's happening to me?
Has anyone experienced severe side effects from Spironolactone? Not long after starting (no more than 1 month afterward - less, if I remember correctly) I began to have neuropathy-like symptoms in my feet, including burning, painless twitching, stinging pain in my big toes, and increased sweating. A few weeks later I developed debilitating pain/tightness along my clavicles (mostly just below) and in my shoulders. I often can't shrug/lift my shoulders (or pull them back to kind of stretch/open up the chest area) without INTENSE pain. It's like all the muscles have shortened. The pain has spread into my upper arms, neck, and head as well. It feels like a mix of more traditional, achey type muscle pain and sharp, stabbing nerve pain. It's really unlike any pain I've ever had before. The pain in my head is a tension headache/sinus pressure combo. It often feels like I'm wearing a very tight headband, or like there's a vice around the back of my head clamping down on the sides. I also have painless muscle twitching, mostly in my legs and bicep/front of my neck.
I am properly hydrated (I drink lots of water, no coffee, soda, or alcohol) and my potassium serum levels have always been fine when checked. I know Spiro can deplete some vitamins/minerals, including folate, but I’m wondering if this could be hormonal. I’ve read mixed information on how Spiro affects estrogen/progesterone levels. Some websites claim that Spiro raises estrogen. Others say it has anti-estrogenic effects and can lower it. Which one is correct?!
Any thoughts? I feel like I’m dying, to be honest. I stopped the Spiro about a month ago but the symptoms are persisting. I’m shoveling down magnesium and folic acid supplements, along with other helpful things like fish oil, a b-complex, etc., but still feel terrible.
I did discover some very interesting posts here from CamperKat about shoulder pain she experienced, but for her it was AFTER she stopped taking Spiro. Mine began very shortly after starting to take it. My doctors insisted my symptoms were unrelated to the Spiro, and I was so desperate to stay on it that I believed them. That might have been the worst mistake of my life. I was on the Spiro for just a little over two years. And yes, I quit cold turkey, but I honestly don't really feel WORSE than I did while taking it, so...
I'm thinking of getting some of my hormones tested through Direct Labs, as I'm sure my doctors will just roll their eyes if I try to request it from them and insist everything's all in my head. It's their "Basic Female Hormone Panel" that measures testosterone (total & free), estradiol, DHEA, insulin, and progesterone. Would this be a good place to start?
I'm wondering if the Spiro might have made me estrogen dominant with low progesterone? Does anyone have any advice for me? The pain is so terrible that sometimes I just want to eat a bullet and be done with it all. I can't live like this much longer.