by Jessica M.


I'm 32 years old.

I started using natural bioidentical progesterone cream 3 months ago, because I think I have progesterone deficiency because I have PCOS and I didn't have regular periods. Even if I had my period earlier I had very bad cramps and brown spotting sometimes. I also noticed some estrogen dominance symptoms like: breast tenderness, bloating, insomnia, irritability, axiety, depression, weight gain around the belly and hips, hair loss, craving for sweets.

Since I started using the progesterone cream I established normal 27-28 day long cylces. (I used the cream in the second half of the cycle for 10-12 days applying the cream 2x 5-10mg a day only. It seemd like it worked and I felt pretty good in my skin but all of a sudden after two months the estrogen dominance symptoms got stronger. I knew that if you have estrogen dominant symptoms it will get stronger because of the cream so I was kind of prepared.

I was trying to figure out what to do because someone said when your period starts then you stop the cream, then later another person said if I have PCOS I have to use the cream nonstop. So I got very confused meanwhile. And these are the instructions what I got for the dosage: Cycle day 1-10 apply 20mg cream at night, and then from cycle day 11- the start of your period apply 2x20mg. I started to follow this and now I just had a cycle of 19 days only and again with bad cramps and mood swings. I also started to consume milled flaxseed daily cause I read that it helps with facial hair which I also have because of the PCOS.

I currently have the cream from Bountifulbird, it says its naturally derived from plant sources (Bountiful Bird bioidentical USP progesterone is derived from wild yam). Formulated to meet Dr. John Lee\'s strict criteria, each 1/4 teaspoon of Bountiful Bird Phyto Plus progesterone cream provides 20 mg. of bioidentical progesterone and 60 mg. of phytoestrogen supplements.

So my questions are: how much cream should I use a day to overcome the estrogen dominant symptoms? Is this cream what I have good?

What's up with the phytoestrogens? If I consume it in flaxseed form does it make my symptoms worse? So many confusion on the internet everywhere...

Thank you!

Comments for Confusion

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Aug 12, 2019
by: Joy

Hi Jessica

I agree, there is a lot of confusing information out there, often by misinformed people. You are not using progesterone cream correctly. Please consider using a good organic cream such as Natpro which is a 3% cream. Nothing less than 100mg is needed. Use half the amount in the morning and the other half at night. This will help to keep progesterone levels stable. As this website states, usually between 100-200mg is needed but often, depending of how severe symptoms are, more is needed. You would have to experiment to see what works for you best, but I suggest starting at 100mg and see if it will help with your

As your cycles are not regular please use the cream every day with no breaks. Continue using every day until your cycle becomes regular. You can then start to use the cream by following your cycle as explained on the How to use Progesterone Cream page. In other words, the cream should be used during your luteal phase once your cycle becomes regular. There is a lot of information on this page which explains all about progesterone. Your adverse symptoms certainly do indicate Estrogen Dominance.

I have never heard of flaxseed helping with facial hair before. Flaxseed is slightly estrogenic which would add to estrogen dominance symptoms. Please read this page where Wray explains all about phytoestrogens.

Make sure that your Vitamin D3 level is correct. Vitamin D3 is very important, a deficiency reduces the benefits of progesterone. Nothing less than 5,000iu's per day is needed. Optimal range is between 70-100ng/ml. Magnesium and vitamin K2 with no soy are important co-factors needed when taking vitamin D3. For more information on the importance of vitamin D3 please read The Vitamin D Council.

Aug 13, 2019
by: Jessica

Hi Joy,

Thank you for the quick answer!

I am now using progesterone cream 100mg a day as you recommended.

So can I really apply it anywhere on my body? cause usually they say apply it on the thin skinned areas on the body, and that's what I did so far...

Can I exhaust the receptor sites and no longer absorb the creme If I use it everyday?

Basically I read in a PCOS forum from a girl that she was consuming milled flaxseed which helped her to get rid of her facial hair. Then I googled it and this is what I have found:

I don't know if the information is reliable at all, what do you think?

I am just starting to take D vitamin today, 5,000iu's per day as you suggested.

Currently I'm taking everyday:

-250mg magnesium together with 1.6mg of B6 vitamin.
-2x470mg Astralagus root for better blood circulation
-1 2000mg Milk thistle
-1 1000mg Saw palmetto.

I also ordered Zinc and E vitamin.

So this very day my symptoms are still a little tender and swollen breasts even though my period is over for 2 days now. I still have mood swings during the day, I feel very sensitive and I could cry about anything.

Since I live in Hungary there are not so many progesterone creams here, and If I order from abroad is very expensive so its a little hard.



Aug 14, 2019
by: Joy

Hi Jessica

Continue with 100mg but please give it time to work. Progesterone therapy is not an overnight fix. If you find that it is not helping then increase to 200mg, you may need to use more. The cream can be used anywhere on the body. It makes no difference if you use it on thinner skin or not, that is another Progesterone Misconception sadly. I have used progesterone every day for 15 years now and it certainly hasn't exhausted receptor sites. What nonsense.

The article clearly states that flaxseeds are plant based estrogens which, as mentioned only adds to estrogen dominance symptoms. However, if you feel that they are helping you, then use them. As mentioned, I am yet to come across a person where flaxseeds have helped with facial hair. The internet can be very confusing, so do be careful.

Sep 05, 2019
Natpro cream
by: Jessica


I have finally bought a Natpro 100g cream.

So do I understand correctly that 1 pump will have 50mg of progesterone?

So if I need a 100mg of progesterone in total for a day then I do 1 pump in the morning and 1 at night?

Thank you!

Sep 05, 2019
Natpro Cream
by: Joy

Hi Jessica

Correct. One full pump delivers 50mg cream, so two full pumps delivers 100mg cream.

Sep 13, 2019
Natpro dosage
by: Jessica


I have been using now the Natpro cream for 9 days. I used 50mg in the morning and 50mg in the evening. Since my estrogen dominance symptoms became active (breast tenderness, depression, irritation, cravings..) I have increased it to 150mg per day for the past 2 days. I use 50mg in the morning and 100mg in the evening. Is that good? I mean I cant really divide the 150mg into two since 1 pump is 50mg.

Sep 16, 2019
Natpro dosage
by: Joy

Hi Jessica

You can divide the amount used to suit you as long as it is no less than twice a day.

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