I am 54 years of age in full menopause and have been taking 600 mg. of prometrium for 2 years. I haven't been sleeping well for the past 5 months and losing weight is an impossible task. As a matter of fact, I could gain it just by breathing. The doctor tells me that I have exhausted my adrenals by overdosing on prometrium all this time and that I should stop immediately. He says it has interfered witth my cortisol. I have followed you for time now and I have problems believing that this is the answer. I just wanted to know how you feel about this advise. Just to clear things up, for the majority of the two years, I felt great. This just started about 5 or 6 months ago. I am worried about what will happen if I stop. Should I stop or maybe cut it down considerably? I don't know what to do.