Two miscarriages

by Molly
(MN)

I conceived once, have a healthy two year old and am now trying again but have suffered 2 miscarriages in a row.

My husband and I started trying to conceive and we were pregnant the second month of trying. We were devastated when I started to miscarry at 6 weeks. I had an ultrasound and the miscarriage was confirmed. The midwife told us to wait 2 cycles to try again and we waited.

The first month we could try we got a "pregnant" on a digital pregnancy test... we were thrilled, only to have the bleeding to start again the next day. I went to my clinic to get a Beta Hcg. The results were not good - 6.5. I go back to tomorrow for another beta.

My midwife thinks I may have a progesterone deficiency since I get pregnant very easily, I just cannot sustain the pregnancy. I go back to the doctor in 2 weeks to hopefully get labs done to find out if this is my problem. I hope to experience the most beautiful gift in the world again with treatment.

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Two miscarriages

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Nov 03, 2008
 Two miscarriages
by: Wray

Hi Molly, I think your midwife is correct, it does sound very much as if you have a progesterone deficiency. Usually conception is not a problem, particularly if you've already had a child, but if the corpus luteum does not make enough progesterone to sustain the embryo, you will miscarry. This most commonly occurs in the first 6-8 weeks.

The lab test might not show you have a deficiency, as it's only occurring when you're pregnant. You might find the mini microscope more helpful than the pregnancy test, these are not very accurate, as the Hcg needs to be quite high before it's detected on a home kit.

See: http://en.wikipedia.org/wiki/Pregnancy_test

We do have a web page on conception and pregnancy you might like to look at:

http://www.progesteronetherapy.com/faq-conception.html

It gives all the info you need on how to use the progesterone from ovulation to it's use in pregnancy. I would also follow the good advice from your midwife, and have a break again of about 2 months before trying again. I do hope you get your wish! Take care Wray
May 26, 2009
 Two miscarriages too
by: Andrea

Hi Wray, I just had my 2nd consecutive misscariage in about 6 months. I misscarried very early for both pregnancies like before 4-6 weeks. I also have a 1.5 year old. I am 34 and I think progesterone levels may be the issue. I was prescribed an oral progesterone pill that is natural not synthetic that I am told to start taking as soon as I have a positive pregnancy test. I would like to know if anyone out there has had any luck with progesterone and healthy deliveries.
May 29, 2009
 Two miscarriages too
by: Wray

Hi Andrea. It very much sounds as if it could be a low progesterone issue. Oral progesterone is not very affective, the better delivery systems are injections (painful!), suppositories or creams. I prefer the cream as it's more versatile as you can apply it where ever it's needed.

"Orally administered progesterone is rapidly metabolized in the gastrointestinal tract and its use has proved to be inferior to i.m. and vaginal routes. Progesterone i.m. achieves serum progesterone values that are within the range of luteal phase and results in sufficient secretory transformation of the endometrium and satisfactory pregnancy rates. The comparison between i.m. and vaginal progesterone has led to controversial results as regards the superiority of one or the other in inducing secretory endometrial transformation. However, there is increasing evidence in the literature to favour the use of vaginal progesterone."

And:
"Progesterone can be delivered orally, intramuscularly and vaginally. The oral route is the least efficient but the intramuscular route is as efficient as the vaginal route"

And:
"However, antiproliferative effects on the endometrium have been demonstrated with progesterone creams when circulating levels of progesterone are low. Thus, effects of topical progesterone creams on the endometrium should not be based on serum progesterone levels, but on histologic examination of the endometrium."

I would recommend you switch to a cream or suppositories. I am currently helping a few women who've have miscarriages and who are now pregnant and using progesterone. I've also helped those who have now had their babies and were also using progesterone! Please see our web page here on pregnancy for more info.

Take care, Wray.
Mar 04, 2010
 I'm unsure
by: Kayla

I just experienced my 2nd consecutive miscarriage in almost a year. They both ended at 19 weeks exactly. With the first I thought that it was my husband and my fault only because we were having sex when my water broke. There was no pain, no blood, just this big gush of clear fluid running down my leg. I have never been so scared in my life until a couple weeks ago when I was walking into my mother's kitchen. At 19 weeks it happened again, my membranes pre-ruptured. This time around there was blood maybe 20 minutes later, but no pain. But like the first the doctors said they couldnt do anything and the cord prolapsed much earlier than the first time. They're going to run a test in a few weeks on my uterus and hopefully I get the autopsy report from my son saying that there may of or may not was an abnormality. Right now I'm just scared of whatever the doctors are going to say because besides them saying there were no infections, or it wasnt our fault we are in complete darkness right now. I'm 23 years old and I can not bring a healthy full term child into this world and no one can tell me why, and it hurts. I just would like to know something.
Mar 04, 2010
 I'm unsure
by: Wray

Hi Kayla. It is difficult to say why it's happening, it could be you also need progesterone. Although miscarriages are more common in the first 6-8 weeks, they can occur later, as can pre-term births. Progesterone is also administered then. Please read this web page, it might give you more insight into pregnancy. Take care, Wray
Mar 09, 2010
 2 miscarriages
by: Anonymous

2 years ago I met a very handsome man. 2 months into the relationship I found out that I was prego... What a surprise! I was scared, happy, worried, in love with this little person. I went to the DR because I started to bleed. They told me that everything was "OK" and that I was 6 weeks along. Well the bleeding got harder and harder. Me never have been prego before thought that maybe it was normal because everyone that I talked to even the DR said I would know if I was losing my baby. I went to a different DR 2 weeks later and found out that I lost the baby. A year and a half went by and I became prego again. I was so happy! I wanted this baby more than anything. I was ready to beome a mom and my husband was ready to become a dad again. I didn't want anyting to go wrong with this one so I started my prenads right away. I got my DR appointment right away. I was ready. Well we went to the DR and we found out that the baby was 6 week and 5 day old. We watched "yolkie" baby heart beat. We were told that even though I had a miscarriage he told me I was a low risk and I had nothing to worry about. On my birthday I was 10 weeks and 2 days along. I went to the ER because I started to bleed and I found out that the babys heart stopped beating at 8 weeks and 5 days. I was destroyed! I loved that little baby more than anyting. I wanted it more than I have ever wanted anything. My DR told me that I could start trying after my next cycle. And I will be. I will have a very hard time with conception because I have opcs. But we will try again, and hope for the best but I will never go to that DR again. So to all you out there that have had this don't give up keep trying. I know I won't till I become a mom
Jul 29, 2010
 2 miscarriages and on progestorone
by: Anonymous

It's comforting to know I am not out there alone. I have a healthy beautiful 2 1/2 year old daughter. We had no issues in the pregnancy with her and everything went perfect. My husband and I decided to start trying again for a second child and had a missed miscarriage the first time at 7 weeks and a blighted ovum at 8 weeks. My doctor has just prescribed me a vaginal progestorone that I need to take as soon as I get pregnant again. I am torn on whether or not to start trying because I don't want to have to live thorough another dissapointment and D&C. Is there anyone out there who went through this and was put on progesterone that ended up with a baby?
Aug 01, 2010
 2 miscarriages and on progestorone
by: W

Hi there Please take heart, many women have had recurrent miscarriages and went on to have healthy children. I was one, I had 5 miscarriages before having my daughter. Unfortunately I knew nothing about progesterone then and how it would have helped. I also knew nothing about it when I had my daughter and developed post natal depression, also due to a sudden drop of progesterone. If you do try again, you need to start using progesterone well before you fall pregnant. Even when pregnant oestrogen dominance can occur if supplemental progesterone is introduced. Certainly not something any women needs to get when pregnant. For more info please see our page on Oestrogen Dominance. We've helped many women who've had recurrent miscarriages with progesterone cream, it works as well as injections, often a choice for doctors, or suppositories, the preferred choice of women as they are painless. For more info please see our page on Progesterone application methods. If you do consider it, please use between 100-200mg/day. Once pregnancy is confirmed I suggest you use at least 200mg/day for the first 3-4 months, as this is the critical period. But please see our page on Pregnancy, it will give you an idea of how to use progesterone, when to use it and how it helps. Take care Wray
Oct 17, 2010
 Two miscarriges dare to try again
by: fulla

Two years ago I had a termination at about 8 weeks because we were not ready. I already have two children. Four months ago we started trying and got pregnant I lost it at about 6 weeks and then I had a period so straight after that I tried and got pregnant .This time I lost it at about 8 weeks, I am really desperate to have another child but I am really afraid to try again. And it is a good feeling to feel that you are not alone.
Oct 22, 2010
 Two miscarriges dare to try again
by: Wray

Hi Fulla Most miscarriages occur in the first 8 weeks, and almost invariably it's caused by a lack of progesterone. Stress causes them too, but simply because stress drops progesterone levels sharply, causing the miscarriage. Please have a look at our page on Pregnancy, it gives all the info you need to know about using progesterone from conception on. Take care Wray
Jan 07, 2011
 with in a yr
by: Kelly

I had 2 miscarriages in 2010 the 1st one I was 4 months along they omited me in the hospital they took 20 vials from me i still have no answer then i got pregnant in aug i lost baby #2 end of oct. i was 12 weeks 4 days they took more blood from me still no answers they said my progesterone level is fine 11.7. We don't know why this is happening they wanted to put me on clormid but I don't have trouble getting pregnant is keeping the baby past 4 months we have a health daughter who's almost 4 i had her full term i had no problems with her. We want to give her a sibling so bad I'm 34 1/2 my husband is 36 what can we we do?
Jan 12, 2011
 with in a yr
by: Wray

Hi Kelly I agree, you don't need clomid, as you have no trouble falling pregnant, but sustaining it. This is often a progesterone problem. Please avoid the clomid, if you want convincing please see these papers here and here. Taking progesterone levels after a miscarriage, is like looking in an empty stable and saying 'oh yes there was a horse there'! Progesterone drops sharply after a birth or miscarriage. During the first trimester levels range from 11.2 to 90ng/ml, yours should have been much higher than 11.7ng/ml at 12 weeks, 4 days. Stress drops progesterone levels, have you had more stress this past year, than when you were pregnant with your daughter? Over and above the stress of the miscarriages. It certainly won't harm to use progesterone for your next pregnancy, but please start it before you fall pregnant. Oestrogen Dominance can occur and it's best not to have this while pregnant. We do have a page on Pregnancy, please read through it, as it explains how to use progesterone. There are plenty of research papers too. Take care Wray
Apr 24, 2011
 i just want to be a mom.
by: nicole

Hi wray, I feel like I have been on a roller coaster with pregnancy. About five years ago I got pregnant and was totally in love with that baby. Sadly, I miscarried him at about 25 weeks. There were no answers for me or any testing done so I never did hear why it happened. It was very hard and because I was only 20 at the time, my husband and I decided to wait awhile. We were both terrified of it happening again and needed some time to get over it. Well, five years later we both felt more than ready to try again. I had my iud removed and shortly after I got pregnant. I miscarried at five weeks. I got pregnant again after one cycle, amd I am currently miscarrying at almost 8 weeks. I read up on the progesterone deficiency and I am wondering if this isn't my problem and considering there was no tests run after my first loss, maybe this is reason for that as well. I have noticed with both miscarriages this time that about 1-2 days before I miscarry I suddenly become very depressed and angry. I couldn't stop crying about everything that happened about two days before I miscarried this time. And that's just not me. I refuse to give up on becoming a mom someday and any advice in helping me sort out this problem would be so much appreciated.
Sep 23, 2011
 Two miscarrieges
by: Alessandra

I also have two miscarriages this year. Is though
Iwish you good lock and hope for a good news this time. I have a 5 years old boy who born premature but thank God is healthy. Me and my husband are 38 so we hoping we can conceive soon.

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