Taking progesterone to stop miscarriage

by Sonja
(Australia)

I have suffered from recurrent early miscarraige. It has been thought that the fact that I have had low progesterone before that this could be contributing to the cause.

So after much research I found out that quite a few women who suffered from recurrent early miscarriage were given progesterone pessaries for the first 12 weeks of pregnancy and were experiencing remarkable success. I unexpectedly found I was pregnant again... so went straight to the drs to enquire about this. She agreed that it was a safe and recommended practice and prescribed me 400mg progesterone trouches to take each night vaginally. My concern is does a trouche get absorbed vaginally as efficiently as a pessary? If anyone can shed any light on this it would be much appreciated... can't help but be anxious through the next few weeks!

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Taking progesterone to stop miscarriage

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Jan 13, 2010
 Taking progesterone for miscarriage
by: Cheryl

Sonja, the vaginal area is a mucous membrane and will absorb very quickly. I use progesterone vaginally because I am post menopause and had a problem with dryness in that area, it has worked great!
Jan 18, 2010
 Taking progesterone to stop miscarriage
by: Wray

Hi Sonja. I'm a bit puzzled about using the troches vaginally, as they are usually made with a sweetener such as xylitol and any number of gums to bind the sweetener and active ingredient. These are some of the gums used: cellulose gum, carboxymethylcellulose, methylcellulose, hydroxypropylmethylcellulose, polyvinyl acid, polyacrylic acid, carbopol, xanthan gum, konjac gum, tara gum, gellan gum, locust bean gum, acacia gum, alginate, carrageenan, agar, pectin, and gelatine. They also have a flavouring added such as mint or orange essence. Troches would not dissolve sufficiently in the vagina, apart from making it sticky! Maybe the term was used loosely? And it was actually pessaries you were given? These are normally made with a soft, easily melted wax or butter such as cocoa butter. As progesterone is lipophilic, a wax or oil would allow better absorption. Please check the label as it should give the composition. If it does contain some sort of gum, plus the other things mentioned above, ask for them to be changed. Progesterone certainly helps with recurrent miscarriages, and you've been given a good dose too. Please see this web page. Take care, Wray

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