Progesterone makes my stomach slightly sick

by Chris
(Carlsbad, ca)

Hi I'm a 39 year old male whose had Adrenal Fatigue, Hypothyroidism and Sleep Apnea for 20 years due to a very dramatic overly stressful relationship with a woman. I've always been kind of shy and reserved but very relaxed at the same. I wasn't aggressive or angry or vindictive before this relationship but at the same time I want as motivated and competive as other boys/men growing up. Anyway this relationship or the stress from this relationship caused me to totally switch over to the anxiety, unbalanced, fearful, needy, unconfident side of me. Any chance of me being who I was calm wise was gone. Since then I started on a roller coaster of Adrenal Fatigue, Hypothyroidism and Sleep Apnea which have gotten worse as time has gone by. I've tried all the supplements and tests and nothing has made a dent in it. I came upon articles for Estrogen Dominance and Progesterone therapy. So I'm really excited and purchased a good cream this past week (before I found this site). My question is at 20 mg I get this somewhat sick feeling in my stomach right after taking it? Do you have an idea why this happens. The Progesterone does relax me and I can feel that it is beneficial but the sick stomach thing made me wonder.

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May 07, 2012
I also noticed...
by: Chris

My body gets cold after I take Progesterone Cream but this only happens after i take it and goes aways after the 1st 45 minutes or so...i warm up again.

The only time i put on it on my neck my thryoid seemed to react. The only reason I know this is cause I have experience with this due to being Hypothryoid and knowing how stress affects that.

May 09, 2012
Progesterone makes my stomach slightly sick
by: Wray

Hi Chris I'm delighted you're open to the idea of progesterone. So many men, women too, think it's only a female hormone, which is not true. We make the same amount as you do, except in the luteal phase it shoots up. Stress of any kind upsets us dramatically, I'm sorry you've been through all that. I've had one woman with sleep apnea write in saying the progesterone had stopped it, whether it will for you I don't know. I have rather a convoluted way of looking at research studies. I've found one paper which states that sleep apnea is associated with erectile dysfunction, see here. I'm not suggesting you have that, but I have other papers that say progesterone does help in erectile dysfunction, and therefore I wonder could it possibly help sleep apnea? See here and here. A further paper here says progesterone is effective for hypoventilation syndrome, but it's affects on sleep apnea are less clear. It does expand lung volume, and is very good for any respiratory problems. Progesterone is very calming too, I'm glad you've found this. We have a page on Anxiety with more info. By relieving the anxiety, it should help the adrenal stress. Oestrogen causes nausea as it activates substance P, see here, which in turn causes nausea and vomiting. Substance P also causes pain and inflammation. It can prevent the conversion of progesterone to allopregnanolone (THP) a potent anxiolytic and analgesic, see here. Unless enough is used, see here. What is now happening to you is the initial Oestrogen Dominance effect. The amount of progesterone you're using is stimulating oestrogen, which in turn is stimulating substance P etc. I normally suggest increasing the amount to overcome this phase quickly, but I can't tell you how much you'll need. It is trial and error. I recommend men use 10-100mg/day progesterone, but we do have one man using 400-600mg/day for extreme stress. Continued below.

May 09, 2012
Progesterone makes my stomach slightly sick
by: Wray

Hi Chris We also have other comments from men you might be interested in reading here, here here, here, here, here and here. Please have a vitamin D test done, as a low level affects the thyroid hugely, see here, here and here. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray



May 09, 2012
Hi Wray
by: Chris

I know my big problem is Adrenal Fatigue. It's what's causing the sleep apnea. I think I'm hypothyroid and I stressed my Adrenal glands trying to have energy when there really wasn't. So my biggest issue is Adrenal Fatigue but I think I was Hypothyroid first. I'm sure it will all unravel after I start taking care of one of them. How much progesterone should I take daily if I'm extremely stressed out? I can tell it's already helping me because I do feel more balanced. I am currently taking 100 mg a day but feel like I could feel better. I'm still extremely stressed out.

May 10, 2012
I also noticed...
by: Wray

Hi Chris This is very interesting. It seems being a man you are far more sensitive to the stimulating effect progesterone has on oestrogen. Maybe because women suffer so many problems they barely notice another. Oestrogen lowers body temperature. Normal oral body temperature in adult men and women ranges between 33.2–38.2 °C (92–101 °F). Typical average temperatures are 37.0 °C (98.6 °F). In women it varies between the follicular and the luteal phase. During the follicular phase, i.e. from the first day of menstruation to ovulation, it ranges from 36.45 to 36.7 °C (97.6 to 98.1 °F). During the 12-14 day luteal phase, i.e. after ovulation to menstruation, temperature increases by 0.15 - 0.45 °C (0.2 - 0.9 °F) due to the increased metabolic rate caused by rapidly rising levels of progesterone. Temperature ranges between 36.7 - 37.3°C (98.1 - 99.2°F) during the luteal phase, but drops down to follicular levels within a few days of bleeding. So this is another oestrogen dominance symptom you're experiencing. I would again suggest increasing the amount you're using. It would appear the stimulating effect is causing problems with your thyroid too, oestrogen slows it down. Take care Wray

May 10, 2012
Im taking 100 mg....
by: Chris

Hi Wray,

Im currently taking 100 mg and am noticing some changes. I do feel more relaxed but then will feel more anxiety than normal at other times when it seems to "wear off". Again I've been under a ton of stress which has definitely broken me down in every way. My question is should I up the daily dosage and how much should I go. I know you say up to 200 mg for men Is acceptable and to go by symptoms but any suggestions how how far to go? My symptoms improve but I can see where there is room for a lot more. In other words my symptoms haven't gone away but then I've only been taking progesterone for about a week.

Thanks.

May 11, 2012
Im taking 100 mg....
by: Wray

Hi Chris I see another query has come in before I could answer the first, so will do them both here. With all the stress you've been through it would be amazing if your adrenals weren't stressed. I would hope the progesterone helps them, it can do so in a number of ways. Firstly it reduces the stress response by activating the GABA receptor sites, GABA is one of the most calming neurotransmitters. This stops the brain sending emergency messages to the adrenals to make the three stress hormones, cortisol plus adrenaline and noradrenaline. Which obviously gives the adrenals a break. Secondly progesterone is the precursor to cortisol, by supplying additional progesterone as you're doing, it relieves the strain on the adrenals having to produce it before conversion. But if cortisol and adrenaline are too high, they have adverse effects on the body, progesterone can suppress them if enough is used. Incidentally zinc lowers cortisol if you feel it's high, see here and here. Excess oestrogen suppresses zinc, so it wouldn't surprise me if yours is low. It's also most important for men, as sperm contains high amounts of zinc. I'm delighted you've increased the progesterone, as I gathered from your first query you were using 20mg/day and it caused a sick feeling, I take it the higher amount doesn't? But if you say you feel anxious again when it wears off, how often are you using it. It should be applied a minimum of twice a day. But I have some who are using it hourly for bad symptoms. You might consider doing this for a bit. As for how much, it's so difficult to say, but the more severe the symptoms the more is needed. For instance they give 1200mg/day to Traumatic Brain Injury victims, over 70% are men too. I mentioned one man using 400-600mg/day, it is trial and error, and only you can tell how well it's working. As you say you've only been using it for a week and it's already helping, I've found with women it can takes weeks if not months to get relief. Continued below.

May 11, 2012
Im taking 100 mg.... part 2
by: Wray

Hi Chris There are other nutrients you could take too, they are given on the anxiety page. One I take daily for calming is taurine, it's also most important for the heart. Glycine is another calming amino acid, I take this too. Another you could consider is tyrosine, it's essential for any stressful situation, cold, fatigue, emotional trauma, prolonged work, sleep deprivation, it improves memory, cognition and physical performance. I also take this. Please don't rely exclusively on the progesterone, the healing nutrients are very important. All your neurotransmitters will have crashed, you need to supply your body with the precursor aminos to bring them up again. And please don't forget the vitamin D, I've found combined with progesterone it has even more benefit. Take care Wray

May 15, 2012
Hi Wray
by: Chris

I was taking up to 100 mg of Progesterone for about a week and I think my Adrenal gland are too shot to handle the estrogen effect the Progesterone is having on it. I can barely handle anything that makes me jitter or stimulated. That's how show my Adrenal glands are. I was putting the Progesterone on my throat at times to see what kind off effect it had on my Thyroid. I stopped taking progesterone because I was getting too jittery while increasing from 20 to 40 to 60 to 80 to 100. I think going up too fast caused this. Anyway I purchased the Amino Acis you recommended to me in this thread and they will help me relax. I didn't have them when I was doing the Progesterone the last week or so. I know you say to increase Progesterone until symptoms decrease but it was too much. I couldn't slow down because of the stimulation. My fear is epinephrine getting to be too much and even though I ordered L Thyrosine I might hold off and go with the Glycine and Taurine because I don't want to increase Epinephrine. Thoughts Wray on all of this? Again I'm a 39 year old male who thinks Estrogen Dominance is causing my issues with Adrenal Fatigue, Hypothyroidism and Sleep Apnea. When I stopped the Progesterone my Hypothyroidism symptoms returned with a vengeance and by this I mean I became really Hypo Thyroid wise.

May 17, 2012
Hi Wray
by: Wray

Hi Chris I so value your continued feedback. I'm delighted you are getting the aminos, they certainly help calm, but it's not an overnight fix. You're very, very depleted and many things have to be sorted, healed, before you'll feel well again. You might like to see this complex here, it has all the nutrients I suggested to you, and more. The B vitamins are essential too, as they drop with stress. I do understand your wariness about the tyrosine, but don't forget it is the precursor to dopamine too. In fact it's from dopamine that adrenaline gets converted, dopamine rises first. So you could try a very small dose and see how you feel, increasing gradually. Your thyroid could do with it too. Iodine and selenium are also essential for the two thyroid hormones. If you feel your iodine could be low, an easy way to find out is to get a tincture of iodine. Put 3 drops anywhere on the inner arm, rubbing them in with the dropper. If the patch fades in a few hours it means there's a deficiency. Continue applying it until the patch takes days to fade. Or take a supplement, see here and here. This is a site here you could look at for adrenal fatigue. His protocol is very expensive, cheaper versions can be obtained elsewhere. Please don't forget the vitamin D, it really is essential for every cell to function normally. The way you're reacting to the progesterone certainly suggests oestrogen dominance. I've found the same in women too, the more oestrogen they have the worse the symptoms when starting progesterone. Increasing gradually as you did is not a good thing, as it keep stimulating oestrogen with each increase. I've found it's always best to go very high initially, this usually suppresses any oestrogen, ensuring progesterone becomes dominant. It was evidently working, as you now say your thyroid has slowed dramatically. I can only suggest you try a very high amount next time you attempt it, like 200mg/day. But don't increase to this gradually, for instance use 100mg in the morning, and 100mg at night. Any time you feel you're getting jittery, apply more as soon as it occurs. Take care Wray

May 18, 2012
Hi Wray
by: Chris

You really think 200mg will work? I have enough to try it. I bought extra. I'm just worried about my Adrenals. I definitely didn't do enough the first time around. I was only doing 100mg towards the end and thats when I started to get even more jittery. I started using sea salt in water the last few days and it does make a difference. When I first started the Profesterone my Thyroid reacted very positively but it was Adrenals that couldn't keep up. I quit smoking about a month ago after 20 years of smoking and my Thyroid went down really bad. I had the worst Hypothroid symptoms. My bodies energy system literally stopped to conserve. It was so bad but it improved after 2 or 3 weeks. When I stopped the Progesterone after that week or so of being on it my Thyroid did the same thing all over again and it sucks! I don't like it. Thoughts?

May 19, 2012
I forgot to mention
by: Chris

Big reason I quit smoking was because my dentist found some white spots on my gums and he thought they might be cancerous so he reminded I quit and said they would go away. I thought I should mention it since Progesterone I read can cause Cancer even though much of what I read says that's not true. This was the last thing I forgot to mention. So that's everything.

May 19, 2012
Hi Wray
by: Wray

Hi Chris I can only ask you to try the 200mg/day. I'm learning a huge amount from you and your experimenting, and so appreciate your feed back. We have many men who use it, but it's rare for any to come back with comments or experiments which then allow me to help other men. Oestrogen dominance is oestrogen dominance, no matter if it occurs in a man or woman. As I've had far more experience with women, I do know that low amounts of progesterone merely make matters worse. I always advise them to use high amounts initially to overcome it. In some instances 400-500mg/day if symptoms are severe, yours are. This is 10-20 times the 'normal' recommended amount women are told to use, ie 20-40mg/day. About 2-5 times higher than the amounts I suggest women start with. I'm pleased you tried the salt, it was something I should have suggested. The adrenals need it, in spite of the fact we are told to restrict salt. You might be interested in reading what Ray Peat has to say about it here. Progesterone does speed metabolism slightly, whereas oestrogen slows it down. This would explain why your thyroid suffered when you stopped using it, as it allowed oestrogen to rise again, adversely affecting the thyroid. Oestrogen is an excitatory, inflammatory hormone. Progesterone has analgesic, anti-inflammatory, anaesthetic, antioxidant and anxiolytic properties. These are a few more articles by Ray Peat in which he mentions progesterone's role in stress and the adrenals, see here, here. and here. Did it ever occur to your dentist that the white spots could have been Candida? Probably not, as it's usually dismissed as inconsequential. Oestrogen exacerbates it, progesterone is protective. Progesterone is also protective against some cancers, see our page on Cancer. And Ray Peat again here. Take care Wray


May 24, 2012
How long...
by: Chris

Hi Wray, how long do you think someone like me would have to take Progesterone to overcome estrogen dominance. Years, months? How long till your body rebalances something like that? So when it comes to dosage we just take enough till our symptoms go away or are lower or what? Thanks.

May 25, 2012
How long...
by: Wray

Hi Chris This is always a difficult question to answer, and I get asked it all the time. I have found the more oestrogen present the longer it takes. But that using high amounts of progesterone it's suppressed far quicker than using low amounts. If you're still using the 100mg/day, and still have adverse symptoms, I would suggest you either increase the amount. Or if reluctant to do that, persevere with it. Please make sure you get your vitamin D levels up, as that makes a world of difference I've found. In fact the people I correspond with who have levels up to 90-100ng/ml feel so much better than those with lower levels. Mine is currently 92ng/ml. You could try taking Calcium D-glucarate. Oestrogen is metabolised in the liver by glucuronic acid, the process is known as glucuronidation. Glucuronidation is one of the major detoxification pathways of the liver. It removes carcinogens, toxins, tumour promoters, the sex hormones ie, the androgens and oestrogens, mineralocorticoids and glucocorticoids, aromatic and heterocyclic amines, polycyclic aromatic hydrocarbons, various nitrosamines, drugs, fungi etc. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase reverses the glucuronidation process. It breaks the glucoronide bond between a toxin and glucuronic acid, and releases carcinogens, toxins and excess steroid hormones back into circulation. There's evidence beta-glucuronidase activity is increased in breast and prostate cancer. Calcium D-glucarate inhibits beta-glucuronidase, see here, here, here and here. Incidentally this enzyme is produced by undesirable gut bacteria, supplementing with probiotics suppresses the bacteria, and subsequently the beta-glucuronidase. Silymarin from milk thistle also inhibits beta-glucuronidase, plus it helps the liver detox. Take care Wray

May 25, 2012
Hi Wray
by: Chris

I started taking the progesterone again. If this helps my thyroid like it seemed to do the first time I took it would I have to take it forever like people with hypothyroidism have to take thyroid meds? Or would my hypothyroidism eventually balance itself out and go away?

May 26, 2012
Hi Wray
by: Wray

Hi Chris I would hope your thyroid balances itself in time. You've been through great stress, all your organs will be suffering. It will take time and patience to heal. Incidentally many hypothyroid problems are caused by a lack of vitamin D, see here, here and here. Please make sure your level is high enough, stress drops levels. I know I sound like a broken record when it comes to vitamin D, but I've found huge benefits occur if the level is high enough. Take care Wray

May 26, 2012
Pregnenolone
by: Chris

Hi Wray, how do feel about using Pregnenolone instead of Progesterone? Would it be better for Men Testerone wise? I'm 39 yrs old so I'm not in the young range age wise but not 50 years old. I feel as if my Testosterone could be higher.

May 27, 2012
Pregnenolone
by: Wray

Hi Chris Pregnenolone is the precursor to both progesterone and DHEA, it's not something I would recommend to a woman. DHEA can increase testosterone levels which are dangerous for a woman. If you're concerned about your libido, then we have many men using progesterone to increase theirs. There seems to be strong evidence that it's progesterone responsible for libido and not testosterone, see here, here, here, here, here, here, here, here and here. If I'm on the right track, your problem is more likely low dopamine, this is essential for a normal sexual response, see here, here, here, here, here and here. Continued below.

May 27, 2012
Pregnenolone Part 2
by: Wray

Hi Chris Dopamine drops sharply with any stress. A drop in dopamine increases levels of prolactin, the hormone of lactogenesis, but also an inflammatory hormone, increased prolactin causes a drop in libido. I did ask you to try taking tyrosine for your thyroid. But it's also the precursor to dopamine, and the stress hormones adrenaline and noradrenaline. Your level will be low. Tyrosine is essential for any stressful situation, cold, fatigue, emotional trauma, prolonged work, sleep deprivation, it improves memory, cognition and physical performance. Acute, uncontrollable stress depletes dopamine, leading to depression and a rise in cortisol and prolactin, tyrosine reverses this. The rate limiting step in dopamine synthesis is the enzyme tyrosine hydroxylase. Insufficient levels of vitamin D inhibit tyrosine hydroxylase, resulting in a disturbance in the dopamine pathway. Please make sure your vitamin D level is high enough. Take care Wray

Jun 01, 2012
Hi Wray
by: Chris

I started taking 200 mg of Progesterone cream last week and in that week I got a cold. Do you think I could taking antibiotics and still continue with the Progesterone cream supplementation?

Jun 04, 2012
Hi Wray
by: Wray

Hi Chris I would avoid the antibiotics, they do nothing for a cold which is caused by a virus. If you really do need to take them, please take probiotics too. There should be a gap of a few hours between the two, as the antibiotics kill the probiotics. Please increase your vitamin D too, a cold or flu is usually the result of too low a level in the blood. I never get them any more as my level is so high. Please let me know how you get on with the 200mg/day. Take care Wray

Jun 07, 2012
100 mg
by: Chris

Hi Wray,

I've noticed in my few weeks of trying Progesterone Cream that at 100 mgs a day I'm fine. Anything less or more is too much. I start to feel "charged up" and that's probably not good with Adrenal issues. I do 100 mg in one dose. I don't split them up into 2 50mg doses because it doesn't seem like enough. The one 100mg dose works. Not too much, not too little. When I take too little I feel like I feel like a took a ton of Niacin, like a huge Niacin flush.I can't sit down for nothing.

Jun 08, 2012
100 mg
by: Wray

Hi Chris I'm pleased you've found the optimal amount, it does require experimenting to find it. I've found it can vary over time too, due to stress, dark winter days etc, which drop levels, so please watch for this. I'm interested too little causes a niacin like feeling, evidently your adrenals reacting. Take care Wray

Jun 16, 2012
Hi Wray
by: Chris

Ive been using the Progesterone Cream for 2 1/2 weeks now and have been doing 80 to 100 mgs a day. Any less is too little and any more is too much. 80 to 100 mgs seems to be best amount. I still have the Estrogen symptoms when I use the cream. My question is will my Estrogen receptors finally "calm down" after a while or will they stil react every time I use Progesterone Cream? I know 100 mg a day isnt a ton but I am a Male.

Jun 18, 2012
Hi Wray
by: Wray

Hi Chris I'm pleased you've found the optimum amount. It does take time for things to calm down. I've found it can take 3 months, and in some women up to 6 months. It depends on how much progesterone is used, and how bad the symptoms were in the first place. You were extremely stressed, and probably still are, so it will be a slow process. It might be an idea to try using it more frequently, ie smaller amounts spread over the day. Please stick at it, and I do hope you're still taking the calming aminos. Take care Wray

Jun 18, 2012
Reverse condition
by: Chris

Hi Wray,

I heard because Progesterone builds up in fatty tissues that people with Estrogen Dominance can change become Progesterone dominant after some time using a lot of Progesterone cream and suffer the same symptoms of Estrogne Dominance. I personally don't beleive it but wanted to see what your thoughts were. Sorry for the many questions but this is very interesting to me.

Jun 20, 2012
Reverse condition
by: Wray

Hi Chris I don't mind how many questions you ask me, I'm learning from your own experience which is invaluable to me. Not many men are as forth coming as you are! I have done a page on Progesterone Misconceptions where I mention this fatty build up. Unfortunately because it's fixed in people's minds, including the medical profession, that progesterone is a female sex hormone, very few studies are done using men. Although male rats are used! So it's a question of extrapolating the info from the female studies and applying it to men too. Luckily the studies done on Traumatic Brain Injury victims show it's not a female hormone, and it most certainly is not a sex hormone. Over 70% of the men in the studies are men, heaven help them if it were a female sex hormone! It plays no part in the secondary sexual characteristics which occur at puberty. I can't get my head around some of the illogical thinking. Oestrogen and testosterone surge during puberty, converting a child's body shape into either a male or female one. In women progesterone is only secreted in substantial amounts once puberty ends, and ovulation occurs. So how can it possibly play a role in the developing sexual characteristics when it hasn't been produced! By saying it builds up in fatty tissue, they are implying progesterone is a static hormone, and remains so. But it's broken down into many metabolites, some within seconds or minutes after secretion or supplemental use. It's the most fundamental hormone there is, certainly the oldest too. You might be interested in reading a page I did recently on Progesterone and Vitamin D. I find the similarities between the two so fascinating I had to do a page on it. Take care Wray

Jun 27, 2012
Growing Hair
by: Chris

Hi Wray,

I just noticed this last week I'm starting to get hairier. Hair on my stomach and back is starting to grow. There was some hair but now its spreading and it hadn't done that for the last 4-5 years. The hair has always been there but now it's spreading. Isn't that weird.

I've been using Progesterone Cream for 3 1/2 weeks now.


Do you know what's happening? I'm also going to be 40 years old in a couple months so that might have something to do with it but I swear for the last 4-5 months the hair is spreading. Do you think it could be the effect the Progesterone Cream is having on my Thryoid? I've definitely noticed differences in how the cream affected my Thyroid when I started using it. Again I'm a 39 yr old male.

Thanks.

Jun 29, 2012
Growing Hair
by: Wray

Hi Chris This is most interesting. I've actually got no idea, as in a female progesterone actually stops hair growth. In fact if a woman had told me this, I'd me dismayed and so would she! I take it you are pleased? It could be something to do with your thyroid, although I have no papers to show this. If I do find anything out I will let you know. I don't think it's got anything to do with your age. Take care Wray

Jun 30, 2012
Testosterone maybe?
by: Chris

Hi Wray,

I thought it was weird. I've been doing the Progesterone Cream for about a month and then recently started taking Maca as I heard it could help balance hormones. I started that about 2 weeks ago. Maybe together they are increasing my testosterone levels. I've always had sparse body hair and now it's really coming in. My body hair has been the same for 20 years. The only other reason I could think of was my age. Getting hairier as I get older. I don't know. It's strange to change suddenly in that respect after I recently started doing the things above. I will keep you posted on my progress with the Progesterone Cream.

Chris

Jul 01, 2012
Testosterone maybe?
by: Wray

Hi Chris It could be the maca, although I don't have papers on increasing hair per se. But it does have some affect on hormone levels. You could look through the papers I have found, there aren't many, and see if you can pick up a possible connection, see here, here, here, here and here. Take care Wray

Dec 08, 2012
hair loss
by: Michael

Hi, found an interesting interview with progesterone research pioneer Katharina Dalton mentioning hair loss. The whole interview is quite interesting too:
http://www.natural-progesterone-advisory-network.com/PDFs/dalton.pdf

Q:One way to get progesterone back in men, to have it be widely accepted, is to look at its effect on hair growth, is that correct?

KD: Yes, certainly, it works, in women’s hair growth. Many women lose some hair shortly after pregnancy; they’ve had a lot of progesterone, and suddenly the progesterone goes down, and they have hair loss, total hair loss sometimes, in some unlucky women. But give them progesterone, and their hair regrows amazingly. I can give you many examples of hair growth in women, but I don’t treat men. And, you know, there is a genetic effect of bald men: they tend to have female offspring with polycystic ovary disease. So if I am querying whether someone’s got polycystic ovary disease, I will certainly ask about male family members, whether they are bald, which would give me another clue, wouldn’t it? For men, should topical progesterone be given once or twice a day? And even for women who are getting their HRT topically, once a day versus twice a day? Which is, in your opinion, the best? First of all, I don’t know men at all. But for women, I find once a day is adequate for the group that does not require it for menstruation, that is, for the nonmenstruating, postmenopausal group.

Dec 09, 2012
hair loss
by: Wray

Hi Michael Thanks for this, I'd not seen it before. I have put together a page on Hair Loss, prompted by queries such as Chris's. Plus many women complain about it. There is a link between PCOS and androgenic alopecia, in as much both seem to be affected by Insulin Resistance. In fact one paper is entitled Polycystic ovary syndrome in men: Stein-Leventhal syndrome revisited There's more info plus all the papers on the Hair Loss link I've given you. It appears to be caused by oxidative stress, as most of our modern diseases are. Often due to a lack of vitamin D. Take care Wray

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