Progesterone deficiency and auto-immune arthritis

I scored 22 on your Q. I've had chronic systemic sero-negative (type HLA B27) arthritis for a long time. After a childhood with no serious illneses, but an acute challenge to immune system at 19 with a big wasp stinging, 2 years later... first signs of bursitis at 21 and I have been in difficulties with widespread pain and severely reduced mobility since 1993.

For years I went it alone, am at present in the care of a rheumatologist, currently taking anti-tnf's (biologics) with unclear/mixed benefits. I have long wished rheumatology would talk to endocrinology... specialisms are a bane in treatment of chronic illness in my view.

Female, 46, perimenopausal, have had children, tendency is for high... even sometimes v high BP, not low BP.

Any precedent for observing role of progesterone therapy in sero-negative arthropies? Answers here also be of interest to people with Crohns, psoriasis, ulcerative colitis, diverticulitis, anklosing spondylitis etc.

Many thanks for any feedback.