Progesterone and multiple sclerosis

by Janet
(UK)

I have been on Chemotherapy (Mitoxantrone) as a treatment for multiple sclerosis every 3 months for the past 9 months. I was wondering if anyone has any experience of or comments to make about MS, Chemo and Progesterone treatment.

The chemo is not working that well as I believe it is supposed to pretty much halt the progression of MS and I have only experienced a week or 10 days a month when I feel well. My menstrual cycle nearly stopped initially but I believe I ovulate and my symptoms worsen in the weeks following. I have had very light or very heavy bleeds.

Any comments welcome.

Comments for Progesterone and multiple sclerosis

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Sep 18, 2008
Progesterone and multiple sclerosis
by: Wray

Chemo is the usual treatment for MS, but there is much evidence progesterone regenerates nerves. Emory University have been studying it for 20 years now and have found it remarkable for brain trauma victims, who were given it via IV transfusion. Incidentally 71% of the patients were men.

It reduces programmed cell death and the synthesis of inflammatory factors that can kill neurons hours to days after traumatic brain injury, promotes regeneration and myelination of axons, has a neuroprotective and antioxidant effect in injured nervous system, has multiple effects on glial cells, it influences growth, differentiation and increases the expression of myelin-specific proteins in oligodendrocytes, and potentiates the formation of new myelin sheaths by Schwann cells in vivo and finally it enhances remyelination in degenerative disorders.

Because of the success with TBI and the fact progesterone helps nerves regenerate, they are going to do a study on MS patients, also stroke patients, as they believe it could help. We know a number of people who have used progesterone successfully, but like all natural things, it's not a quick fix. Hope this helps.

"Local synthesis of PROG in the brain and the neuroprotective and promyelinating effects of this neurosteroid offer interesting therapeutic possibilities for the prevention and treatment of neurodegenerative diseases, for accelerating regenerative processes and for preserving cognitive functions during aging." See
here. Take care Wray

Oct 06, 2008
Chemo and MS
by: Trish

No, chemo really isn't the usual treatment for MS. It is one option for those who are moving onto secondary progressive.

I did that treatment, among many others, and found that it just increased the likelihood that I would get a UTI, which triggers an episode, etc, etc. I stopped it. I've ended up on Tysabri, plus paying attention to my food allergies and I'm doing much better.

Good luck, Trish

Sep 26, 2010
chemo and progesterone cream
by: Anonymous

I was using progesterone cream (Dr. Lee's) for about six months before I had a malignant brain tumor removed. I was taking it for hot flashes etc. I kept taking it while on chemo, and I still have my periods and my hair has not fallen out despite three rounds of chemo. So I have no intention of stopping it.

Oct 03, 2010
chemo and progesterone cream
by: Wray

Hi there I'm pleased the progesterone helped you, it's helped others. You might like to read these two pages Progesterone healed my radiation burns in days and Progesterone returned my body to a healthy cycle following chemo Take care Wray

Apr 04, 2013
LDN
by: Linda B

Please check into LDN (Low Dose Naltrexone) as treatment for your MS.....

Read "The Promise of Low Dose Naltrexone Therapy" and definitely read "Up The Creek With A Paddle" by Mary Bradley Boyle...

Apr 05, 2013
LDN
by: Anonymous

Not that familiar with chemo and progesterone cream for MS, but would suggest you check out LDN (Low Dose Naltrexone; My niece got her life back with LDN. Must read: "Up the Creek with a Paddle" and "The Promise of Low Dose Naltrexone Therapy".

Apr 06, 2013
Please check into LDN (Low Dose Naltrexone) as treatment for your MS.....
by: Wray

Hi Linda B Thanks for this info, I see someone else had made the same comment too. There's a lot of scepticism over naltrexone, except for it's use in opioid addictions. For which it appears safe if appropriate doses are taken. If it helps MS then I see no reason for avoiding it, or listening to the sceptics. If it's the placebo affect at work, that's also fine! There's mounting evidence a lack of vitamin D increases the risk of MS, if not the direct cause of it. There are studies on progesterone too. Take care Wray

May 28, 2014
MS Progesterone, Chemo and Turmeric
by: Frango

Re MS I have seen amazing results with women using progesterone cream.
French Professor Billeau ?? about 2000 ?? proved in his sponsored research that both the real hormone or synthetic (eg Provera)would re-mylenate the axons but he was going to leave it to the drug company to develop a specific synthetic progesterone that would target the axons. I felt this was criminal not to tell the world. It works, Ive seen it. Synthetic is not good generally. Avoid it. resarch Dr John Lee and Dr Ray Peat.

Re Chemo + Turmeric. Check out Australian ABC internet news. Turmeric increases the efficacy incredibly for colon cancer chemo. (UK Uni and Pharma company combined research.)
Also check Turmeric + Black pepper. Indian scientist in USA showed incredible increased efficacy. Vitamin C molecule also is restored in presence of Turmeric. This is just the tip of iceberg of research of old old spice.
Great as anti inflammatory for my Prostate too.

May 29, 2014
Chemo for MS Jan? You sure?
by: Frango

To Jan UK
i don't know anything about Chemo for MS but almost shudder at the thought after learning so much about Progesterone to re mylenate the axons. Researched the research for 12 months then daughter broke her MS news. Well in the next month did more research than previous 12.
If you have an emotional reason to research anything you'll excel more than ever. Seems like this website likes real progesterone and please research www.Johnleemd ?? John R Lee. He died but his team is doing wonders.
Anti-inflammatories (natural ones) needed to help the inflammation where the immune system is attacking the lesions in the nerves. Turmeric is amazing. Daughter lived 8 good years on Progesterone but got sick of applying the daily small dab. Three weeks on, one week off. Her choice. Chronic progressive MS. Know several ladies-no MS symptoms any more.

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