Hysterectomy and Progesterone Cream

I have had a Hysterectomy over 7 years ago ago and I began using Progesterone Cream for a couple of years to alleviate symptoms. However, I felt better and stopped. I also notice an insert was inside the box of progesterone cream that I used and it mentioned possible side effects including cancer. Now my hot flashes have come back and I am confused about a cream that I thought had no risks attached to it.

Should I consider using progesterone cream again? Also since I have had a hysterectomy is it ok for me to use just progesterone?

Comments for Hysterectomy and Progesterone Cream

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Sep 04, 2007
Progesterone cream and cancer
by: Wray

There is no evidence that progesterone causes cancer, in fact quite the opposite.

There are many research papers showing it prevents breast, ovarian and endometrial cancers. So please don't be concerned about it's use. It will help the hot flashes too. And yes you can use just progesterone after a hysterectomy.

As it is the precursor to both oestrogen and testosterone, if you need either of these, the body will make what is required from the progesterone. Take care

Aug 22, 2010
Estrogen cream
by: Anonymous

I am on both estrogen and progesterone cream, had a complete hysterectomy. Is this OK? I still have some hot flashes.

Aug 26, 2010
Estrogen cream
by: Wray

Hi there I don't believe any woman needs extra oestrogen, we get more than enough in our food, water, air and skin care we all use. In fact too much, for more info please see Our Stolen Future website. You might like to read our page on HRT too. Hot flushes can be helped, even stopped by progesterone, but only if enough is used. The amount needed is 400mg/day for 4-5 days, then reduce slowly. Take care Wray

Jun 21, 2012
Progesterone and anti-Clotting
by: Anonymous

I have used Progesterone cream for 20 years, and swear by it, but was a bit worried about something I read that it prevents clots. I am soon going to have a knee replacement, and that kind of open surgery can have a lot of bleeding. Do I want something that has anti-clotting benefits, or would I want the opposite. I don't know if I should go off the Progesterone until the surgery is done. What would be the safest?

Jun 23, 2012
Progesterone and anti-Clotting
by: Wray

Hi there I'm delighted you've used progesterone for so many years! I'm not sure how much you're using, but if it's the 20-40mg/day normally recommended there is no concern. This amount does not raise progesterone to levels found in the luteal phase, see Progesterone Misconceptions. If it's high as some women use, ie 500-1000mg/day, I would suggest reducing it slightly. Take care Wray

Aug 19, 2012
Just starting Progesterone Cream
by: Robin

I am just starting on Prosesterone Cream and I am curious, will it help reduce the amount of pesky peach fuzz that keeps growing on my chin? Ever since I had my total hysterectomy I keep getting it there. I have never had any type of hormone replacement and my doc has finally given me this creme. She waited 12 years because I have a brain tumor and cancer.

Aug 21, 2012
Just starting Progesterone Cream
by: Wray

Hi Robin The peach fuzz is caused by testosterone, and progesterone does suppress it, plus if bound to SHBG (sex hormone binding globulin) testosterone becomes inactive, progesterone raises levels of SHBG, see here, so preventing the rise of free testosterone. SHBG drops if sugars are eaten, even those found in all grains, legumes, dairy and sweet starchy fruits and vegetables. Fructose, sucrose and glucose, reduce SHBG by 80, 50 and 40% respectively, see here. It's best to avoid all the foods and sugars mentioned. I'm not sure how much she's advised you to use, but I recommend 100-200mg/day for it to be effective. We do have a page on Menopause with more info. Progesterone has been used successfully in many Cancers, please look through this page we have. Please have a vitamin D test done, a lack of it leads to a greater risk of getting cancer. Plus a lack reduces the benefits of progesterone. Both Progesterone and Vitamin D work synergistically. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital websites. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

Sep 16, 2012
Bioidentical HRT
by: Ann

Following a total hysterectomy in 2010, I was given estrogen to take. The side effects were awful, headaches that would last for days, sweats, and sleepless nights, not to mention anxiety and panic attacks. After seeing a Dr Phil program about bio-identical HRT, I found a physician who finally listened to my complaints and prescribed a combination of estrogen, progesterone and vitamin supplements.This was 6 months ago. Within a week I felt completely different. Now 6 months later I feel like my old self, no panic or anxiety attacks, the headaches are rare and I feel like I am living my life again. Progesterone certainly has worked for me.

Sep 17, 2012
Bioidentical HRT
by: Wray

Hi Ann I'm so happy to hear this. It's typical to dish out HRT, as if progesterone was not worth considering. Unfortunately it's regarded as the pregnancy hormone and nothing is known about the other roles it plays. It's actually fundamental to every cell as it affects the way genes express themselves. Take care Wray

Oct 19, 2012
Progesta-care Cream
by: Lori

I had a total hysto 6 weeks ago. The doctor didnt send me home with any estrogen like he say he would. On the 9th day I was crying and the next day I was angry....etc.. On the 10th day I went to the local Natural Vitamin store told the rep my story and he gave me Progestra-Care will assurance that it was what I needed. The first night I rubbed it on my thighs and I immediately had great results! Since the 10th day, I have had NO problems and am back to my youthful self and feel better than I have in years! Sex drive is back, happy, lighthearted. Today, the estrogen pills came in the mail, but I am feeling wonderful and playful and dont want to do anything to mess this up. Must I take estrogen???? Am I hurting myself in the long run. I am healthy as a HORSE and have even lost weight.

Oct 20, 2012
Progesta-care Cream
by: Wray

Hi Lori I'm delighted the progesterone worked so quickly, and with the low amount you are probably using. There is no need to take the oestrogen, if you want convincing, please see our page on HRT. It's most extraordinary that oestrogen is the only hormone they think about. Progesterone also drops after a hyst. Please keep a watch for any Oestrogen Dominance symptoms, as these can come out of the blue. Increase the progesterone if they should. Take care Wray

Oct 21, 2012
by: Lori

Wray, thank you for the comment. I am well adjusted and feeling great. I will drive on as I have been. I use one pump amount a day as directed and calculated already on the container. Thanks again!

Oct 26, 2013
Pro-Gest Use
by: Vicki H

I had a hysterectomy 15 years ago (in my mid 40's) and Dr immediately put me on estrogen, and I have had no problems. At 57, I decided to stop taking it and after several months of night sweats and hot flashes, it leveled out which was tolerable. Now, at 62 years old, they have come back, with vengeance! I went to the doctor and explained that I had lost 30 lbs in the last 6 months and wondered if that could have caused the flare-up? Because I have had a thyroidectomy many years ago and have been on synthroid since, she did a blood test which came out good. She said she did some research and that weight loss can cause menopause symptoms to return. So, anyway, she put me on Vivell-Dot .0375 mg which after a few days did nothing. So I went to the local health store and Pro-Gest was recommended and after the first day of using it, I slept through the night without any night sweats!!!!! My question is, the instructions are not clear...do I take it twice a day, everyday? And when I do decide, because of my age, I want to stop it and see if I am clear of the symptoms, do I just stop or do I have to wean myself off slowly? Thanks for your help?

Jul 08, 2014
Progestrone cream
by: Anonymous

Sorry but that is SUCH a LIE ! It does NOT cause cancer. I've been on it for 10 years. Its the synthetic one that does

Oct 31, 2014
total hysterectomy a week ago
by: dd

Ive looked all over the internet for answers on what to use. My doc sent me home with minivelle estrogen patch..first day I used it severe headache, sec day I removed it. Felt better. LEF organization is the bomb for advisors and vita d, DHEA, and Progesta care cream. Set me up with s Bio identical doc today! Blood work on Monday to see what my levels are. He suggested nothing but vita D 5000mg a day and DHEA plus progester care cream until blood work comes back...no estrogen. Thank God I waited.

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