Can you clear up my confusion?

by Penny

I was told by my Dr. to buy a progesterone cream that is natural progesterone USP which has a molecular structure identical to the progesterone produced by the human body.

She said natural progesterone is produced through the fermentation (and other steps) of the Mexican Wild Yam. She said it must say progesterone USP and not just wild yam extract. Why does yours not say that and why is it derived from soya-bean? Thanks for your help.

Comments for Can you clear up my confusion?

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Mar 23, 2010
Can you clear up my confusion?
by: Wray

Hi Penny. The progesterone used in Natpro is USP. The web site says here: Progesterone Ph. Eur., USP, JP (origin: soy). The full names are below, followed by their abbreviations:

European Pharmacopoeia (Ph. Eur.)
Japanese Pharmacopoeia (JP)
United States Pharmacopeia (USP)

It doesn't matter what the source of origin is for the progesterone, there are many plants which can be used. Phytosterols, erroneously called plant oestrogens or phytoestrogens, are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone, they are used as starting points for the synthesis of progesterone. Soya bean and yams are the two most common sources. The progesterone in Natpro uses the soy bean as the starting point. Take care, Wray

Oct 11, 2011
Progesterone USP
by: Susan

Wray, thank you for the detailed information on your website, and the care you clearly give each case and inquiry.

You mention in this thread that the progesterone used in Natpro is derived from soy, however, would you happen to know whether the soy used is certified as organic? This appears to be of increasing importance given the genetically modified soy which is in almost all processed foods and products. The GM version of soy out there has been lab tested and shown to be harmful/toxic, so I've been trying to obtain the organic version whenever possible.

Thanks in advance for your response.

Jan 03, 2012
just posting to see reply
by: Anonymous


I'm not sure why you need to do this, have you been having difficulties getting them in the past? Take care Wray

Mar 14, 2013
Can you clear up my confusion?
by: Norway

Wray, is the soy in Natpro organic?

Thanks in advance for your response.

Mar 16, 2013
Can you clear up my confusion?
by: Wray

Hi there There's no soy in Natpro, the progesterone is synthesised from plant sterols found in the yam. Take care Wray

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