Progesterone for Parkinson's Disease?

by Patty

Hi Wray! I just found your site a couple days ago and I am really enjoying it!!
I too have done a lot of reading about natural progesterone for at least 20 or more years.
My husband found out a couple yrs. ago that he has Parkinson's Disease. I did research and found out how magnesium can really help with some of the symptoms. I am not at all surprised to see how all my reading and research are now fitting together like a puzzle!!

I give you a lot of credit for comprehending the way the body and hormones, vitamins, minerals, enzymes, neurotransmitters, etc... all interact and are dependent on one another.
In fact, I never knew until now about how we need to have magnesium before taking Vit D!!

While doing research for my husband's condition, I also found Dr David Perlmutter. It is so great that his latest book, "Grain Brain" has become a NY times best-seller!!
I would like to know your take on how natural progesterone cream can help my husband. I am planning to buy your Nat Pro. I currently have the Progest.

I am 51 and my husband is 61. He had always been so youthful. Everyone always said, "he can do anything!" (Jack-of-all-trades). :)

His muscles are very weak and he started having terrible pain trying to stand up from a squatting position. I noticed some tremors when he would hold a spoon to his mouth. He would excessively drool in his sleep. He drags his feet when he walks and has worn out heels on his boots.

The most heartbreaking thing which I can't bear is to see his cognitive abilities getting worse.
Some days he seems his old self, other days he will pause so long before he answers me.
He can stare at and go over the same info on a bill or letter.

I am the type of person that does not follow the old school way of medicine.
When I had 2 large cysts the size of grapefruits near my ovaries and the doctors talked hysterectomy, I knew "NO WAY!!!" Because of that, I found a doctor who agreed to just remove the cysts and that's
just what he did!!

Thankfully, because I refused a hysterectomy, my husband and I have a beautiful 18 yr. old daughter!!!

That is about when I started my journey into investigating progesterone.
After my surgery, I was given a synthetic progestin to stop functional cysts from growing on my ovaries.
I feel I was born having anxiety and depression, and at first the fake progesterone almost felt like an anti-depressant!! But then I felt worse.

I found Dr. Lee's books and my quest to understand really took off!!
So, I use natural progesterone cream for myself and would like to know how you think it may help my husband with the Parkinson's. I plan on taking him to see Dr. Perlmutter in person for a second opinion on treatment. My husband will listen more if a doctor tells him to try a natural treatment.

Thanks for reading my story!
You are an AMAZING person Wray with your own amazing story.
I want to thank you SO MUCH for this WONDERFUL website!!
You have truly done your homework and know your stuff girl!! :)

Comments for Progesterone for Parkinson's Disease?

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Jan 14, 2014
Progesterone for Parkinson's Disease?
by: Wray

Hi Patty I've been wanting to reply to your query as it interests me, but have not felt up to it at all, hence this late reply. But firstly thanks so much for the kind words about the site. I'm delighted you've read Dr Perlmutter's book, it's most excellent. He was one of the speakers on the Gluten Summit, an extraordinary conference, good enough for me to buy the videos after it ended as I didn't have the time to watch them all. Dr Perlmutter of course emphasised the importance of avoiding grains, not just gluten. That seems to be the mistake most make, grains also contain opiates which affect our brains. Plus sugars and starches, in particular amylopectin, which is converted to glucose quicker than any of the sugars. Carbohydrates are a large group of organic compounds occurring in foods and living tissues and include sugars, starch, and cellulose. It's classified into three main groups, sugars, oligosaccharides and polysaccharides. The sugars are further divided into.....
monosaccharides such as glucose, fructose and galactose
disaccharides such as sucrose, lactose and maltose
sugar alcohols such as sorbitol, mannitol, lactitol, xylitol, erythritol, isomaltitol and maltitol
The oligosaccharides are divided further into.....
alpha-glucans such as maltodextrins
non-alpha-glucans such as raffinose, stachyose, fructo- and galactooligosaccharides, polydextrose and inulin
The polysaccharides are divided into......
starches such as amylose, amylopectin, modified starches
non starches such as cellulose, hemicellulose, pectins, hydrocolloids (e.g., gums, mucilages, beta-glucans)
The rate of absorption is the determining factor on how the body responds. If rapidly there is a sharp elevation in blood glucose. Usually followed by hypoglycaemia due to the surge of insulin that the pancreas produces in response to rising glucose levels. If there are rapid and large increases in blood glucose this can lead to oxidative stress and to cell, tissue and organ damage. Not least in the brain. The carbohydrates to avoid are the monosaccharides, disaccharides, maltodextrins and amylopectin. Which are found in all grains, legumes, dairy, sweet starchy fruits and veggies. Amylopectin, a rapidly digested starch, must be avoided at all times. For instance all grains contain it, so they should all be avoided. Starches on the whole comprise about 70% amylopectin, with glutinous rice having 100% amylopectin. Continued below

Jan 14, 2014
Progesterone for Parkinson's Disease? Part 2
by: Wray

Hi Patty The brain does not do well on glucose, and only needs a very small amount. It does better on ketones, break down products of fatty acids. Please consider putting your husband on a high fat ketogenic diet. The best and clearest explanation I've found of the 1:1 is this web site on the Basic Ketogenic Diet. The barest minimum should be 50% of his calories from fat. Only the good fats should be used, i.e. MCT oil, coconut oil, butter, lard, in fact any animal fats, cocoa butter, olive oil or macadamia oil. The first six are saturated fats, the other two mono-unsaturated fats. The best is the MCT oil, an extract from coconut oil. MCT oil forms ketones more efficiently than the other oils. The diet varies from a 4:1 ratio of fat to protein/carb down to a 1:1 ratio which is the easier to follow. It's also essential to eat enough protein. This is based on 0.9g to 1.0g of protein per kg per day of lean muscle mass. Contrary to what is generally believed a lack of protein leads to bone loss. Muscle weakness can be due to low Vitamin D levels, please get this checked out, see here, here, here and here. Make sure he's also taking enough magnesium. Myopathy is also caused by a lack of progesterone, see here, here and here. This last abstract has nothing on it, so I've pasted a passage from the paper which I bought... 'Substantial relief of myopathic disability by progesterone therapy'.....
(We report about a 41-year old woman who was suffering from a general muscle weakness since her early childhood....From July 1998 until July 1999 the patient was treated with progesterone suppositorium 0.4 g once a day from the 14th to the 25th day of the menstrual cycle. In July 1999 her gait had improved significantly and she could get up from a chair more easily, even her ability to walk up and down stairs had improved....Progesterone dosage was increased from 400 mg to 600 mg. Continued below

Jan 14, 2014
Progesterone for Parkinson's Disease? Part 3
by: Wray

Hi Patty In January 2001 the patient reported enthusiastically about the improvement she had gained from progesterone-therapy. The patient reported a clear increase in strength in all affected muscle groups resulting in dramatic functional improvement.) BDNF is always low in Parkinson's patients, progesterone does help raise this, see here, here, ere, here, here, here, here, here, here, here, here and here. Vitamin D also increases BDNF, so too does intermittent fasting, see here. It's so important he stops all sweet starchy foods, and gets more fat into his system, much more. Take care Wray

Jan 14, 2014
Wray, Your Concern is Beyond Words!!!
by: Patty

Dear Sweet Wray,

That was so kind of you to respond to my post!!
Especially since you should be resting and your also took time to write 3 parts!! Wow!!! How can I thank you?!!!

I will be looking up the links and info you gave!!
I don't know how you remember about all of this info like the different sugars, etc... Do you paste info about that too?
I research a lot but I don't have the brain to comprehend it all!

The human body truly is a gift from our Creator!!
Scientists who spend time looking even closer at how magnificently the body works so harmoniously together should be moved to acknowledge the existence of a Maker and Master Designer of the human body!!

Well, thanks again so much for your self-sacrificing love for people that you put into your all of your efforts to help people.
You truly are unselfish and have a love for people.

I hope to speak more to you in the future!!

Deep appreciation and warmth,

Jan 15, 2014
Wray is So Sweet!!
by: Patty

Dear Wray,
You are SO sweet to take the time to answer my post!!
Thank you so much for ALL of the research and time you put into this!!

I don't have the brain to remember all of this info like you do about the breakdown of sugars etc..!!
How do you remember? Is that info pasted in from articles as well?

I am looking forward to taking time to look up all of your references!

Do you think there can be a more balanced diet my husband could follow and then take extra supplements for inflammation? To cut most carbs is going to be so hard.
Would having sufficient protein with each meal reduce the insulin spikes so we can still enjoy carbs?

Keep getting rest Wray.
You truly have a deep love for people and it shows.
However, you will be able to help more people if you don't burn out and when you do start working again to have shorter days.

Thank you very much again!
I DEEPLY appreciate it and it truly came as a surprise.
Glad I had just checked my email when I saw you commented!!

Deep Appreciation and Sincerity,

Jan 20, 2014
Progesterone for Parkinson's Disease
by: Joy

Hi Patty

As Wray is on Sabbatical she will not be replying to any further emails or posts.

I do hope that you found the information provided by Wray useful, lots to read and take in.

To answer your question about about a more balanced to for your husband, the answer is no I am afraid. He really does need to cut out all carbs as advised by Wray if he wants real health. Protein also requires insulin, so although it doesn't spike it will still rise if too many of these foods are eaten. By eating a great deal of oils and fats, carbs are not missed, in fact they become most unappetising!

It really is best to follows Wray's advise on this.

Take care.

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