Progesterone cream

by Barbara

I am currently using prog./test./0.15 mg/0.1 ml cream twice daily prescribed by my Dr. and comes from a compounding pharm. I read your articles which states that we probably need 100/200mg daily to be effective. I mentioned this to my Dr. and she said you were probably quoting the dosage used in pill form (which my body won't tolerate), that the cream was much more condensed (for lack of a better word) and all of it gets into my system much quicker as opposed to the pill which has to go thru quite a process to be absorbed in the body and in which case we loose a lot of the effectiveness of the meds. Can you let me know if this is the case, I have been using this for about 6 months and feel no difference in my symptoms except some weight gain (which is impossible to loose). I took the Saliva test and was told my estrogen was extremely high. I am almost 68 yrs. old and definitly thru menopause. I am also using Estriol,1mg daily for vaginal dryness and something called Vulvodinia. Nothing seems to help. Your advise please.

Thank you

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Jan 22, 2012
Progesterone cream
by: Wray

Hi Barbara I do recommend 100-200mg/day progesterone, but not as oral progesterone. Your doctor is quite right, it's not the best Delivery system. The cream is a far better method of getting progesterone into the body. You say you are using 0.1ml of cream, but don't mention how strong the cream is. If it's a 10% cream, this means it contains 100mg progesterone per ml of cream. So the 0.1ml is giving you about 10mg progesterone. If I'm correct, this is one reason you are gaining weight. Progesterone initially stimulates oestrogen production, if the amount used is too low, it will continue stimulating it. We have more info on our Oestrogen Dominance page. Oestrogen is a mitogen, it causes cells to multiply and divide, including fat cells. These are also a source of oestrone, the menopause oestrogen. It's as potent in it's action as oestradiol, the pre-menopause oestrogen. So a vicious cycle starts. Plus you are using testosterone, this should never be given to a woman, it increases visceral fat, hence your weight gain, plus much more, see here, here, here, here, here here, here, here, here and here. I suggest you stop the testosterone and increase the progesterone substantially. We have found using the progesterone cream in the vagina does help dryness and inflammation, it's a potent anti-inflammatory. Although estriol is a safe oestrogen, see here. For more info please see our page on Menopause Take care Wray

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