Just started using Progesterone

by Sean
(Sweden)

I am a 26 year old man just started using natural progesterone today for Adrenal fatigue, prostate inflammation of unknown cause, hair loss, etc.

My morning cortisol value is twice as normal range and I suffer from low libido & weak erection due to Testosterone Deficiency.

After some reading I came across different forums mentioning Progesterone is used in Chemical castration and some guys had written it suppressed their libido even more and causing bladder control problems.

So I'd like to know more about these side effects.

Thank you.

Comments for Just started using Progesterone

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Jul 29, 2011
Progesterone for men
by: Anonymous

Hi, I am a 64 year old male, have and used natural progesterone cream for 8 months now. I am at a 20mg. a day dose of the cream which works for me. I have improved libido, new dark hair at front hairline, all prostate problems are now gone. At first I had a spike in estrogen side effects but that subsided and now I am good. I believe it actually increases testosterone!

Aug 04, 2011
Just started using Progesterone
by: Wray

Hi Sean Unfortunately the word 'progesterone' is used not only for natural progesterone, but when describing the synthetic progestins. These are used for chemical castration and should be avoided at all costs, by both men and women! The jury is still out on testosterone being responsible for libido. In fact it appears more likely that it's progesterone responsible for this. We have many men using it successfully, you might like to read these comments here, here and here. And these papers here, here, and here, here, here and here. It is a potent anti-inflammatory, and I've found it helps adrenal fatigue. The adrenals first produce progesterone, before converting it into cortisol. When stressed, the adrenals rob other sources, which impacts on the reproductive system. I'm running out of space so will start a new comment below. Take care Wray

Aug 04, 2011
Just started using Progesterone
by: Wray

Hi Sean Have you ever had your dopamine levels checked? Dopamine is the neurotransmitter responsible for sexual arousal, see here, here,here, here, here and here. Dopamine levels drop when stressed. It might be an idea to take the amino acid tyrosine, the precursor to dopamine, to raise the level. And to increase your protein intake. We have more info on how to take it on our Natural Antidepressants page. Both excess oestrogen and prolactin inhibit the production of dopamine, where your levels checked? Whereas progesterone increases levels by suppressing excess oestrogen and prolactin. It also raises levels of all the monoamines, of which dopamine is one, as it acts as a monoamine oxidase inhibitor. Monoamine oxidase is an enzyme that breaks down dopamine amongst others. I generally recommend 10-100mg/day for men, but it's safe to go far higher if you feel you need it. But please watch for Oestrogen Dominance, this can occur and is disconcerting if it does. Levels over 1200mg/day are given via IV transfusion to brain trauma victims, over 70% of which are men, see here and here. You live in Sweden, where levels of sunshine are low, consequently vitamin D is low. Please have a test done, a lack impacts greatly on our health. For more info see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital websites. Take care Wray

Aug 05, 2011
Progesterone for men
by: Wray

Hi there I'm delighted you've responded so positively to the progesterone. I've not found one man who hasn't, but they can experience Oestrogen Dominance, just as women can. There are now over 100 oestrogen mimics in our environment, impossible to avoid them now. For more info see Our Stolen Future. You might like to read through the papers I gave Sean. Take care Wray

Aug 09, 2011
Just started using Progesterone
by: Sean

Thanks for your respond dear Wray.

I've been feeling fatigued all my life considering root causes like Hypothyroidism or Celiac. I'll soon have some tests ruled out.

I will also notify you about my prolactin and other results.

I've been taking vitamin D3 for 2 months now, without any changes.

As for Progesterone, I tried it 3 times having a very bad taste (maybe metallic)the day after and strange bladder problems. (Tingling sensation for almost an hour after urination, very annoying and sometimes painful, when sitting).

I wonder what's causing this?

I will also give Tyrosine a try since I suspect Hypothyroidism as well.


Aug 11, 2011
Just started using Progesterone
by: Wray

Hi Sean I would appreciate knowing your results, as any info I receive I can pass on to others. How much vitamin D are you taking? As the minimum daily dose should be 5000iu's or more, depending on the blood level. This should be 70-100ng/ml or 175-250nmol/L. I find a test essential, as it gives an idea of how much vitamin D should be taken. Have you considered Insulin Resistance as the possible cause of your tiredness? If the cells are not getting the fuel they need, tiredness results. You might like to see our page on Nutrition too, to get an idea of what to eat. Especially if you suspect celiac disease, try avoiding all grains to see if it helps. It's interesting you had the metallic taste after using progesterone. This probably comes from adenosine, progesterone stimulates it slightly. Adenosine is a nucleoside which is part of the energy molecule ATP. One of the side affects of administering adenosine itself is a metallic taste in the mouth. Adenosine is vital for energy production, it lowers glycerol levels and is believed to promote sleep. It's involved in the wake/sleep cycle too, see here, here, here and here. The last paper describes the effect progesterone has on adenosine release. It could be your wake/sleep cycle is disrupted for some reason, leaving you tired. Dopamine is also involved in the wake/sleep cycle, see here. I don't know what could have caused the tingling sensation, although both adenosine and progesterone are vasodilators. Could the increased blood flow have done this? Finally a lack of vitamin D impacts on the thyroid, so symptoms of hypothyroidism could be nothing more than a vitamin D deficiency. Take care Wray

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