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Wondering...

by Carol Fava
(U.S. Virgin Islands)

In 1983, while working on a yacht in Spain, I began hemorrhaging and was given a number of vials of progesterone by a Spanish physician. Two years later I discovered a lump in my breast which eventually was diagnosed as breast cancer. No one in my family has had cancer. Could the progesterone have caused my breast cancer or had some affect on its development?
Many thanks.

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Wondering...

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Wondering...
by: Wray

Hi Carol The progesterone wouldn't have caused it. In fact there are many papers showing it has a protective action against breast, endometrial and ovarian cancer. Oestrogen causes cells to proliferate, it also activates a gene called Bcl2 which prevents cells from dying. Progesterone puts a stop to this by activating another gene called p53 which causes cells to die. Hope this helps Wray

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