I have been taking Natpro for about 10 months (3/4 spoon twice a day) and all my hot flushes and night sweats have now stopped, and I'm feeling great apart from suffering from a dry vagina. My sex life is non existant because of the dryness and even with loads of lubrication it still hurts. I went for a smear test and the dryness was so bad that the nurse couldn't complete it. I was in a lot of pain as she tried to do the test and there was a small bleed from the vagina wall. The doctor has prescribed a 15 day course of Vagifem to be taken vaginally (25 micrograms Estradiol) and I will then go back to try again. I have never had any problems before with smear tests. I am very confused about taking the estradiol as you seem to think that we shouldn't take any extra estrogen but I hate this dryness and pain. I have decided to go ahead with the two week course but should I increase my Natpro for the two weeks while I'm on it or should I just continue as I am? Your opinion on this would be gratfully received.