Severe symptoms after using progesterone cream

by Cheryl
(Vero Beach, FL USA)

After not having a period for 55 days and feeling fuzzy and fatigued I decided to try progesterone cream. My Dr. would not prescribe it for me even though my blood work shows I am well into peri menopause. Prior to using the cream i completely upgraded my dietary habits. I ate pretty healthy anyway but decided i'd had enough of feeling good maybe 4 days a month and am desperate to feel good again. I have to say, removing most processed foods from my diet and adding some vitamin supplements i am finally starting to feel half way human again. When i got the progesterone cream i immediately started between 100 and 200 mg. per day. Within 10 days, emotionally i seem to be much better (don't know if it was the cream or just changing up my diet and taking proper supplements). I gained 12 pounds in just over a week and physically i feel horrible. My feet are so swollen i cannot put on shoes and it's painful to walk. My joints are bloated as well as my feet, you can no longer distinguish my ankles. In addition, my belly is so bloated that it appears i am at least 8 months pregnant.

The only thing that i am doing which might cause such a drastic gain in bloating and fluid retention is the progesterone cream. I do not know if it has made me feel better as many of the symptoms i was having have decreased dramatically but this might just be because i am eating all fresh foods, nothing processed. Physically it's a nightmare, the added weight gain over such a short period of time has got me completely wacked out. The only thing i can attribute this to is adding the progesterone cream. It took me a long time to get that 10 lbs. off and i feel horrible that not only is it back but no matter what i do it actually keeps going up. I watched the scale every day for a week go up a pound or two each day.

I stopped the cream for now until i can find the answer for my bloating, fluid retention and weight gain. I assume the weight gain and inches gained in such a fast time is due to fluid retention. Is this caused by progesterone? If so, how long does it stay in your system? I had started to feel a whole lot better just by eating healthier and taking vitamins but went ahead and used the cream anyway thinking it can't hurt. Boy was i wrong. I am fatigued more than ever, have been a night owl for the past two weeks and don't even want to leave my house because i don't even feel it's me underneath all of this fluid retention and bloat.

Oh, i had blood work done in October for a surgery and they also checked my heart, that came out fine and then in January after my annual pap i had blood work done to find out my levels of hormones. The Dr. confirmed i was in peri menopause and gave me a script for anti depressant. I went for a second opinion and got the same answers. I haven't taken the anti depressants as i have been treated in the past for very real depression and i don't think this is the case now. My liver and kidneys as well as my heart are working very well.

Sooooo how long before i can get this progesterone cream out of my system? Will i lose the 10 lbs. i put on over night? I have read real horror stories about the weight never coming off. I can take one bite of lettuce and immediately get bloated and gain 3 lbs. I think i actually liked it better when i had the awful flu like symptoms. At least my clothes fit me.

Please help me. I cannot find anyone to give me a straight answer.

1. How long does progesterone cream take to leave your system? and...

2. Once out of my system will the bloating and fluid retention go away?

3. Is there anything i can do to speed up this process?

I feel worse than i did when i started all of this.

Oh, also, since starting the cream, i am up until all hours of the night therefore sleeping half the next day away. This is the worst nightmare ... i keep hoping i will wake up and be back to my normal size. I want to start walking the beach like i use to but my feet and legs hurt so much i have a hard time walking to my mailbox.

Any advice or help you can give me is highly appreciated. I have written dozens of letters to so called bio identical hormone specialists who say there is nothing i can do, just deal with it. I am so frustrated and sorry i thought the cream would work for me or at the very least, i'd remain the same. i am 5'3" so 10 lbs. on me is like being obese.

Thank you so much in advance. I look forward to your reply. Blessings.

note from webmaster: Sorry Cheryl but our policy is to not publish email addresses as they attract spam

Comments for Severe symptoms after using progesterone cream

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Mar 02, 2011
BHRT
by: Michelle

I sounded alot like you 3 months ago. I found a great Specialist in Denver that has helped me a great deal.Just Google- BodyLogicMD on your computer! Check out this group of nation wide Specialist ! I did and it is amazing the difference it has made in my life. Good Luck !

Mar 08, 2011
Severe symptoms after using progesterone cream
by: Wray

Hi Cheryl Paradoxically it's not progesterone, but excess oestrogen causing the water retention. These two hormones activate the opposite receptor sites, so when first using progesterone Oestrogen Dominance can occur. Ie oestrogen rises. You say you were using between 100-200mg/day, which is the amount I recommend. But evidently you needed a higher amount to over come the oestrogen effect. It's essential to make progesterone the dominant hormone. Progesterone is a potent diuretic and analgesic, so good that it's now being used via IV transfusion for brain trauma victims. It prevents the oedema and inflammation that occurs after the injury, see here, here, here and here. I've found the more oestrogen present in the body, the worse the oestrogen dominance symptoms. Unfortunately oestrogen is rising the world over, none of us can escape it. There are now over 100 oestrogen mimics in our environment, plus the HRT and contraceptive oestrogens which are not removed by water purification plants. See this excellent website Our Stolen Future for more info. The only safe way to counter all this oestrogen is with progesterone. As it's not a sex hormone, it can be safely used by both sexes. So the last thing you need is for your progesterone level to drop too low. You say you had blood work done, please check the ratio between your oestrogen and progesterone levels. We've found from Saliva Tests we run that the progesterone to oestrogen ratio should be 600:1 and over to feel well. Progesterone is also a potent anxiolytic, helping with depression too, please see our page on Anxiety. I feel you could be short of vitamin D too, please have a test done. It's low in most of us, and is a critical nutrient for health. Amongst many things a low level causes depression and insomnia, plus it reduces the benefits of progesterone. For more info please see the Vitamin D council and GrassrootsHealth websites. Blessings to you too. Take care Wray

Mar 13, 2011
Progesterone cream
by: Anonymous

I to have also gained about 8 pounds while I was dieting or it's hard telling how much it would be. The Pharmacist was very educated but did not mention a thing about gaining weight because he knew that most women would not use this product.

I'm getting blood work done tomorrow to see how things are after 2 1/2 months. It has definately taken the hot flashes away but not much more. I am going to look into another product because I do not deal well with weight gain. Any help or suggestions please?

Jun 22, 2013
a year later.....
by: Michelle

Cheryl,

Now that it is a year later, have the pounds come off.

I'm very interested as I am right where you were a year ago. I gained 7 lbs in 2 weeks on a combo of bioidentical estrogen and progesterone.

I hope you can share some good news!



Jun 23, 2013
Cheryl
by: Wray

Hi Michelle I just have to put in a word here. It seems the specialists you went to put you on oestrogen too, it's no wonder you have gained weight. Oestrogen is a mitogen, stimulating cells, including fat cells to proliferate. Progesterone inhibits mitosis, but it will have an uphill battle if it has to fight against oestrogen. I doubt the amount of progesterone is sufficient, with or without oestrogen. You might like to read this page here. Take care Wray

Oct 10, 2013
weight gain & joint pain
by: Anonymous

I know it's the two months on progesterone cream that has caused me a migraine all month and I have gained 10 pounds (and my clothing doesn't fit, I'm 5'1" so it's upsetting also my fingers and feet hurt do much it's bad. I've never gained weight easily. I did a similar weight changes when put on the birth control pill at 18, I ballooned then. I do wish someone who is better would write in after some time after stopping. I know progesterone is a God send for many, but not me. My period was very heavy too and I hoped it would make it lighter, no it was heavier. I have stopped now for about 17 days with pain in my hands and feet the same and my weight is horrible. Now that's not long, it's ovulation time, my first off progesterone. I have noted the headache is better. Nothing else yet, if this following my birth control pill experience (one brand) I believe my weight became stable on a different brand in a pretty short time. I began this because my old and periods are hell this is worse. It did help my cramps, but come on? Maybe the brand does effect it as I am not on the brand on this web site. Anyway I will try to update my changes it stands to reason with any other medication, you stop it and the problem stops. There is no way I'd up my dose. No more of this I have a great fast metabolism and I don't believe I'll have any long term problems. I'm just sensitive. It takes our bodies time so I wouldn't see a doctor for this. I introduced it and it's bad for me. I have stopped and I strongly believe my body is normalizing. This was and is awful. It will get out of my b body very s ion some of the pregnancy sites talk about this problem and it does take time then they are normal again. Acne is bad for some women as well that they say goes bye bye in time too. Our bodies are made by God remove the cause and that's a fix, God willing. If you have been where so m a ny of us are and are normal please write in.

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