Prometrium use topically

I am new to the topical progesterone world. Am weaning myself off of HRT. I currently have over 100 (100mg) prometrium pills and am wondering how to use them most effectively.

If they are micronized progesterone (for oral use), why can't they be used topically instead? They are a milky liquid inside a gelcap. It would be very very easy to drop them into a lowdose progesterone cream. It just doesn't make sense to me to toss them, they were expensive!! I understand that taking them orally is much less effective than topically.

Can anyone give me any info on whether this can be done and how the 100mgs in the gelcap translates into transdermal mgs. Would a compounding pharmacist have this info?

Will order my future progesterone here and keep up to date on the new info. What great info and service you are doing!

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Prometrium use topically

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Sep 19, 2011
 Prometrium use topically
by: Wray

Hi there Thanks for the kind words! And yes, I always suggest using the cap contents transdermally. You can open the cap and either apply it directly to the skin or add the contents to a natural or organic skin cream. I wouldn't bother to get a progesterone cream, as they are more expensive than plain skin creams. Or just add it to some plain organic vegetable oil, the best is caprylic/capric triglycerides, more commonly referred to as MCT oil. It's the lightest of all oils, and not only goes into the skin very quickly, but makes it very soft too. This is one reason we use it as our base oil. As the caps contain 100mg progesterone, you will be getting this if applied to your skin, not if taking it. Oral progesterone is the least effective Delivery system. The best are injections, suppositories or creams. I prefer the cream as it can be applied anywhere. Incidentally you can use the caps as suppositories, I would suggest at night only, in case it leaks during the day. The vagina is an excellent place to use progesterone, as it has a plentiful supply of blood vessels. The progesterone if applied there prevents inflammation, dryness and protects against Candida. I'm relieved you're weaning off HRT, no point in going cold turkey, as symptoms can be harsh. You might find when you start the progesterone that you get Oestrogen Dominance symptoms, due to the extra oestrogen you're getting. I've found the higher the oestrogen level, the worse the symptoms when starting progesterone. Normally I recommend 100-200mg/day, but it's entirely dependant on symptoms, the worse they are the more is needed. So don't be afraid to use more, you might like to read these comments here, here, here and here for encouragement. Take care Wray

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