Progesterone

by Tina
(Canada)

My name is Tina and I'm from a small town up north in Alberta, Canada. 4 years ago I started to bleed very heavily for 9 months straight and I went to see 3 doctors (all male).

They all said the same thing... 'you are pre-menopause. One of them said to go home and think about getting all my woman parts out. I went home and started to look for some help. I talked to a girl at the health store and she said to talk to this woman who is a blood analyst. I made an appointment with her and she put me on natural progesterone cream.

After 4 days my bleeding stopped. It also helped with my other problems I had (headaches, stress and sleeping better). I thank God for the progesterone cream and the blood analyst who is now a good friend of mine... :) It helps for a lot of things... thanks again.

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Progesterone

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Jul 25, 2010
 Progesterone
by: Wray

Hi Tina I'm so pleased you did not have all your 'parts' out! Progesterone does help with heavy bleeding, as many women will testify. For an explanation oestrogen is a mitogen, causing cells to divide and multiply, vital once a month to stimulate the endometrium each month to grow and thicken ready for a possible fertilised egg. But too much and the lining builds excessively. Matrix metalloproteinases (MMP?s) are enzymes that break down protein. They play a role in the breakdown of endometrial tissues at the end of the menstrual cycle. If they are over active, as would be the case with an excess of oestrogen in the body, (oestrogen stimulates it?s production), the result is a pathological reaction such as inflammation and excessive bleeding. Progesterone suppresses MMP's. It?s only when progesterone levels drop at the end of the cycle that the MMP?s can get to work and breakdown the lining causing our monthly bleed. But with oestrogen continually stimulating more lining, and low progesterone, bleeding continues. Oestrogen is an excitatory, pro-inflammatory hormone, progesterone is anti-inflammatory. It suppresses both oestrogen and MMP's. It helps with sleep as it raises levels of serotonin, this neurotransmitter is the precursor to melatonin our sleep hormone. It also helps with stress as it activates the GABA receptor sites, GABA is one of our most calming neurotransmitters. And finally it helps with headaches as it inhibits the secretion of histamine from mast cells. Take care Wray

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