Progesterone Overdose?

by Rachel
(Wa)

Dear Wray,
Despite my attempts to keep my Natpro out of reach from our 3 year old daughter.. She somehow found it and emptied the full tube on her skin. I've only used 2 tsp of the tube. I'm worried that almost 1800 mg can be dangerous to her little body. Is there anything I should do?
I just started using the cream to treat extreme endometriosis and combat terribly painful incisional cysts. I'm out of cream for myself and I'm worried about my daughter.
Thank you for any advise.

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Jun 01, 2015
Progesterone Overdose?
by: Wray

Hi Rachel Yes it is an overdose, but from what I've learnt about progesterone, the only reaction she'll have is one of euphoria, or sleepiness. It can be used as an anaesthetic, although this is generally given via a drip. We have many mothers using progesterone on their babies and toddlers to calm them down, or help them sleep. But please keep an eye open for any other symptom. I can't tell you what, as the the two above are the only ones I know of. During the third trimester we produce up to 400mg/day progesterone, so in effect your daughter has received 4 1/2 days worth in one go. I don't think this is anything to worry about, but as I said please keep an eye out, and please keep in touch. If you have Endometriosis please have your Vitamin D levels checked, they could be too low. You live in Washington, so the chances are they are too low. Magnesium is the most important co-factor for vitamin D, a lack of it can be the cause of pain, please consider taking magnesium too. Substance P is a nociceptive, neuropeptide involved in causing pain and nausea. A lack of magnesium causes substance P to rise, see here and here. Substance P inhibits progesterone, see here, but if enough is used, progesterone suppresses substance P, see here. Oestrogen stimulates substance P, see here. So it's essential to use enough progesterone to inhibit oestrogen. If you'd like more info on magnesium, please see Dr Dean's website here Take care Wray

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