Progesterone in early normal pregnancy?

by Amit
(India, Pune)

My wife's doctor has advised her to take Progesterone.

Dosage: 1 Susten 200/daily internally.

Question: Is it safe and necessary to take this medicine as this medicine has many side effects?

- She is almost six weeks pregnant, and the pregnancy is normal
- during 3 week she spotted 2 brown spots.
- Her Real Time Pelvis Sonography details:

" Anatomically normal urinary bladder.
No evidence of calculus / mass lesion is seen. The walls appear normal.

Normal anteverted uterus measuring 7.2x4.5x3.4 cm. No focal lesions are seen. The endometrium is central.

There is seen a tiny cystic structure measuring 2.7mm in the endometrium - Early gestational sac.

Both the ovaries are visualized and appear normal.

No evidence of solid or cystic lesion seen in the ovaries or adnexae."

- Her BETA HCG (For Blood) is 1316.24, this is done by ELFA: MINIVIDAS technique.

Can you please advise us?

Thanks in advance.

Comments for Progesterone in early normal pregnancy?

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Jul 05, 2008
Progesterone in early normal pregnancy?
by: Wray

Hi Amit. Susten is a natural progesterone and the dose is a good one. But there's little point in taking oral progesterone, as 80-90% is destroyed by the gut and liver as it passes through. It would be far more effective if she used it as a suppository.

Please be assured progesterone doesn't have any adverse side affects. It was probably because she had spotting her doctor wanted her to use it, as spotting is a sign of threatened miscarriage. Progesterone is vital for a successful pregnancy. I will give the web link to info on how to use progesterone during pregnancy:

http://www.progesteronetherapy.com/faq-conception.html

Do hope this helps, take care Wray

Jan 14, 2009
thank you
by: Anonymous

I am currently 3 weeks pregnent and on 100mg progestrone supositories and this information really helps. Thank you.

May 20, 2009
Google it
by: Anonymous

Please just Google Susten 200 or Progesterone to see what the literature says.

Progesterone is NOT authorised for use in any Western country any more for use during pregnancy. It is a very outdated treatment. It is completely unnecessary and moreover, has harmful side effects for mother and baby.

May 23, 2009
Google it
by: Wray

Thanks for your comment, but unfortunately you couldn't be more wrong! Not only it is not harmful, but it is used frequently if there is a threatened miscarriage or pre-term birth. To say it's 'outdated' is to say that the endogenous progesterone we make when pregnant is outdated! All animal's bodies have been making it for 500 million years to support pregnancy. It's so vital that without it we would never produce offspring. Its seems probable that you are confusing bio-identical progesterone with synthetic 'progestins' which are indeed harmful.

Please see the following papers:

Progesterone ? induced blocking factor (PIBF) and Th1/Th2 cytokine in women with threatened spontaneous abortion

Progesterone and the Risk of Preterm Birth among Women with a Short Cervix

Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix

FKBP52 deficiency?conferred uterine progesterone resistance is genetic background and pregnancy stage specific

Recurrent miscarriage and embryonic loss

The changing role of progesterone in preterm labour

Effects of Vaginal Progesterone on Pain and Uterine Contractility in Patients with Threatened Abortion before Twelve Weeks of Pregnancy

Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: A randomized placebo-controlled double-blind study

May 20, 2010
Use of progesterone while presence of fibroids
by: Anonymous

My wife is 13 weeks pregnent. She had spotting in the 6th week and then stopped. We were terified and went to the doctors in london. They completly outruled use of progesterone and reassured us that progesterone does not do anything to pregnancy and NHS in UK does not allow use of progesterone in any circumstances unless it is proved that the pateints body is deficient in producing progesterone. We then were in India and the doctors there has a similar veiw as answered by you in earlier questions. Now my wife has been taking Sustan and Deuphestan regulaly for past 7 weeks and she is fine with all normalities of the fetal growth. She also has 2 posterior wall fibroids and their size has been showing an increase in the scan we had done. Is this normal? Can progesterone cause fibroids to grow? Should she continue with progesterone and ideally till when?

May 22, 2010
Use of progesterone while presence of fibroids
by: Wray

I find the doctor's statement the most remarkable I have ever heard! As you saw from my previous answer to the woman who said progesterone should not be used in pregnancy, it is, and it's vital for sustaining one! Why else would a pregnant woman make so much? The spotting would have been caused by a drop in your wife's progesterone level, obviously not sufficient to cause a miscarriage. But none the less it would have been of great concern to you. Sustan is progesterone, and seems to be the favoured brand in India. But I'm concerned your wife is also taking Duphaston. This is a synthetic progestin, and yes it is given to pregnant woman, and to date there are no known adverse affects on the foetus. But I see no reason for taking it when progesterone is the hormone needed. Oestrogen stimulates fibroid growth, not progesterone, I would suspect the Duphaston has something to do with the growth. All synthetic progestins suppress progesterone, please see here for fibroids. And for more info on Duphaston please see here. And here. Please have a look at a web page we have on progesterone, it might help you to make the right decision. Please also look at the article written by Dr Dalton, there is a link on that page. Take care, Wray

Jun 05, 2010
Concerned
by: Anonymous

i'm currently 4 weeks pg and my doctor prescribed the progesterone Pometrium. I googled it and read that it was not safe to use while pg... what do you think? Should I stop taking it and ask for another brand?

Jun 06, 2010
Concerned
by: Wray

There is so much confusion between progesterone and progestins, even the Prometrium site itself has a warning! I can only assume they put the warning because of the FDA. Prometrium is progesterone, it is not a progestin. Progesterone cannot cause " higher risk of heart attack, blood clots, stroke, breast cancer and dementia" as the site says. If it did, then every pregnant woman would suffer severely from these problems, as levels of progesterone rise hugely when pregnant. In fact the reverse is the case, whereas the progestins do cause an increase in these conditions. Your doctor knows what he's doing, please continue using it. You might like to see our web page on pregnancy. Please see here. Take care, Wray

Jun 07, 2010
Concerned
by: Anonymous

Thanks for responding to my question... I was put on Prometrium because I had four miscarriages and yes I did see the Prometrium site where it said it shouldn't be used in pregnancy, that's what made me so concerned. I will continue using it... Thanks Wray!

Jun 09, 2010
Concerned
by: Wray

Hi there So pleased I could reassure you! If you get fed up using suppositories the creams also work, provided you use a high strength cream and stick to the dose you've been prescribed. ie if you're using 2 x 100mg suppositories per day, then use 200mg in cream form.
Please see here.
And here.
And here
And here
And here
Take care Wray

Jun 09, 2010
Concerned
by: Anonymous

I'm currently taking the Prometrium pills are the suppositories better? What do you recommend? I take 200mg in pills at night only.

Jun 09, 2010
Use of progesterone while presence of fibroids
by: Anonymous

Thanks for your reply to my question on 20th May with above title. I have few more queries. My wife is okay and the baby is growing fine. She is now in 16th week. The doctor has advised her to carry on with Sustain and Deuphaston for up to 7th month.
1. Is this use of progesterone and duephaston completly safe for the baby?
2. Her natural progesterone production and external intake of progesterone, can this become excessive for her and harm in any way?
3. She has a fibroid on the posterior wall and the placenta is on anterior wall, what complications can that cause?
4. How much of the risk is the overall situation considering the above three points and also considering that she had some spotting in her fifth week (only for a day) and then never again.
5. Also in your earlier reply you were worried about use of duephaston but the doctor has assured us that it does not cause any harm and is a standard priscription to many.
Thanks

Jun 10, 2010
Concerned
by: Wray

Hi there The suppositories are infinitely better. Oral progesterone is mostly destroyed as it passes through the gut and liver. Please see here.
And here. Progesterone should always be used twice a day or more, as levels drop after about 13 hours. Creams are as affective as suppositories and are more versatile, as they can be used where and when needed. The dose can be varied to suit too. Please see here.
And here.
Take care Wray

Jun 10, 2010
Use of progesterone while presence of fibroids
by: Wray

Hi there The use of progesterone is completely safe, without it no woman would carry a child to term. It's used in fertility clinics the world over for IVF treatments, to prevent miscarriages and pre-term births. Progesterone is the hormone of pregnancy, nothing more is needed. She was evidently not producing enough progesterone in the early weeks, hence the need for the supplement. But to give a synthetic drug is beyond me. As I said there have been no adverse reports to date, but why give it? Many women use progesterone for the entire 9 months and beyond to prevent post natal depression. No adverse affects have been reported. Your doctor wants to stop the supplement by the 7th month, by then your wife should be making around 400mg/day herself, more than enough to sustain the pregnancy. But her doctor might do a test to check the level, and if it's not this high, he might get her to continue the supplement. I've not had any experience of fibroids and complications with the placenta, it would be best to ask your doctor. I don't believe your wife is in any risk now, as she is now 4 months pregnant and past the dangerous phase when most miscarriages occur. But a check can be run to see what levels are present. Saliva is best and non invasive, unlike blood tests. I think you live in the UK, so visit the Genova Diagnostics web site here. They carry out saliva tests in the UK. Take care Wray

Jul 13, 2010
Is Gestofit safe
by: Anonymous

Hi, My husband and I are ttc for past 3 months but not yet successful. My doctor has prescribed Gestofit 200 mg twice daily from 16th day of my cycle. I am not sure if I am progesterone deficient. Shall I go ahead and take it? On the net I've read that it induces weight gain. I am slim and would not like to gain weight unnaturally. Please advise.

Jul 18, 2010
Is Gestofit safe
by: Wray

Hi there There's not much info on the web about Gestofit, but it appears to be progesterone. I can't find any studies that have been done using it. Unfortunately oral progesterone is the least effective delivery system. For progesterone to have any real affect orally the dose should be a minimum of 300mg/day. I see it also comes as an injection, which is an effective system, but painful if used daily. Suppositories and creams are also effective, please see our web page on Progesterone application methods. You might like to look at our web page on Conception and Pregnancy. Take care Wray

Sep 09, 2010
Advise on Susten200
by: Anonymous

I just completed my first follicular monitoring and on 18th day after Hucog7000 injection my follicle has burst. I am 34 years old and trying to get pregnant for last one year.

Now my Doc has advised me to take Susten 200 orally twice a day for 12 days.

Should I? Have been reading that its not recommended lest I have history of progestorenoe deficiency, which I am not aware of.

Pl help

Sep 19, 2010
Advise on Susten200
by: Wray

Hi there If you have problems falling pregnant and you've been given hCG injections it indicates a severe progesterone deficiency. hCG is a hormone that prevents the the corpus luteum from disintegrating. The corpus luteum produces progesterone after ovulation, progesterone is critical for pregnancy. At about 8 weeks pregnant progesterone production by the corpus luteum starts declining, while the placenta takes over production for the remainder of the pregnancy. For more info please see our page on Pregnancy. I'm not in favour of oral progesterone, it's the least effective means of delivery, please see our page on Progesterone application methods.
Take care Wray

Sep 26, 2010
Progesterone and hypospadias
by: Anonymous

While it is true Progesterone has little side effects, it does have one possible side effect that most people don't mention and that is hypospadias. Hypospadias is when the opening of the urethra is not perfectly centered on the end of the penis in men. There are varying levels of the defect. One of the causes of this is too much progesterone in pregnancy. Now obviously you need progesterone to carry the baby at all, so if you are low then the benefits definitely out weigh the risks. But if your progesterone levels are normal a supplement should not be added.

Oct 04, 2010
Progesterone and hypospadias
by: Wray

Hi there Thanks for bringing this up, it did alarm me at first, as I had not come across it as a possible adverse side affect of excess progesterone. I'm relieved to find it isn't. Hypospadias is the most common malformation of the male genitalia and occurs in 1 in 250 male births. Some studies found a doubling of the rate in the USA between 1970 and 1993. I find this particularly interesting, as it was a time of little concern over environmental poisons, particularly the endocrine disruptors
mimicking oestrogen. In recent research this has come to the fore front as the most likely cause. The male penis expresses receptors for the androgens, oestrogens and progesterone. The androgen receptor has been implicated in the development of a demasculinised penis following androgen exposure in utero. Hypospadias have also been induced by exogenous oestrogen while still in utero.

Of concern here is the evidence that not only the environmental oestrogens, but the contraceptive pill taken in the early weeks of pregnancy causes them. In particular the progestin medroxyprogesterone acetate which feminizes male and virilizes female genitals. One study did find a 5-fold increase risk of hypospadias during IVF treatment, commenting that the only recognised difference being the administration of progesterone, but that the cause was unknown. Another difference which was not mentioned, is the use of FSH analogues or clomifene, both of which stimulate the ovaries to produce multiple follicles, these in turn would produce more oestrogen than normal. Several studies have found an increase incidence of hypospadias in industrialized nations. Confirming that exposure to or ingestion of the following substances while pregnant cause hypospadias. Many of these are oestrogen mimics...... 17 estradiol, the pesticide vincolizin sprayed on grapes, the antihistamine loratadine, the flame retardant benzophenone-2, hexachlorobenzene, a diet rich in fish or shellfish, hair spray, phthalates, alcohol, smoking of the father and progestins. It appears one study found the expression of progesterone receptors suggested a direct role of progesterone in normal genital penis formation. Please see these papers here, here, here, here, The Journal of Urology Volume 178, Issue 2, Pages 722-727 (August 2007 and here. Take care Wray

Oct 26, 2010
Susten 200mg
by: Anonymous

My wife is 5 weeks pregnant. Doctor advised to take susten 200 twice a day. We recently married and this is the first pregnancy. Of course no miscarriage. Different people have diff views regarding this. Can you tell me she can take these tablets?

Oct 29, 2010
Susten 200mg
by: Wray

Hi there Susten is progesterone so is safe to use, but far better if used as a suppository and not orally. Oral progesterone is the least affective delivery system, please see this page on Progesterone application methods, particularly the papers. I'm surprised she's been given them if it's the first pregnancy and as you say of course no miscarriage. Unless her doctor suspects the possibility. Progesterone is vital for a successful pregnancy, for more inof please see this page we have on Pregnancy. Take care Wray

Nov 15, 2010
Susten300
by: Anonymous

My doctor has asked me to take Susten 300 once a day for 15 days. Is it fine? I have PCOD problem and I had a miscarriage earlier.

Nov 15, 2010
Susten300
by: Wray

Hi there Yes it's fine to take it, but far better to use it as a suppository. Oral progesterone is not the best delivery system, most of it gets destroyed as it passes through the gut and liver. For more info please see this page on Progesterone application methods. We do have a page on PCOS. Please read through it as it explains why it occurs and what to do about it. We also have a page on Pregnancy. Please read through this as it explains how to use progesterone for a successful pregnancy. Take care Wray

Dec 23, 2010
Duphaston/Susten
by: Chimp

I'm 7 weeks pregnant and doc did not see the foetus growth. I was on duphaston for last 15 days but another doc asked me to take Susten now.

This is to prevent the possible miscarriage. Pls advise.

This is my first pregnancy...

Dec 26, 2010
Progesterone use
by: Anonymous

Is it ok to use progesterone cream prophylactically? I have had one miscarriage recently. The baby stopped developing at 5.5 weeks, but gestational sack was there and growing. The doctor suspected a blighted ovum, since he could not find the embryo at first. When my blood was taken, at 7 weeks (I didn't know at that time that pregnancy ceased), my progesterone level was 13.5. My naturopath now says that I should start using natural progesterone just in case, when i decide to get pregnant again. What do you think? Is it safe?

Jan 07, 2011
Duphaston/Susten
by: Wray

Hi Chimp Duphaston is synthetic progesterone, often favoured by doctors. Susten is natural progesterone and far safer and more effective. You don't mention how much he's given you, but I recommend 100-200mg/day. If you've had recurrent miscarriages you will need the higher amount. We do have a page on Pregnancy. Please read through it as it explains how to use progesterone during pregnancy. Take care Wray

Jan 07, 2011
Progesterone use
by: Wray

Hi there Yes it is safe, and if you've had a past miscarriage is important. Without progesterone no woman would carry a child to term. We do have a page on Pregnancy. It explains how to use it during pregnancy. It's always better to start it before falling pregnant, as Oestrogen Dominance can occur, not what you need while pregnant. Take care Wray

Feb 05, 2011
Still born
by: Micky

Introduction ? I am 33 years of age and I recently had a stillborn and am looking into various reasons that led to this and the possibility of this happening in the future.
Background ? My LMP is dated to be 2 June 2010. I was expected to give birth on 9 March 2011. Early on in the pregnancy (first trimester) I was told I had large haematomas for which I received hormone injections (Fertigyn 5000 daily) for one month and suppository Susten for the same period. This condition then subsided only to re-emerge which was caught in the Level II ultrasound. Also seen on the ultrasound was a one week lag. I was then recommended a better diet and bed rest which did. At week 28-29 I had a terrible itch, predominantly affecting my legs (soles), palms, scalp, breasts and ears. I then went to the Gynaecologist who suspected that it was related to my liver. I got a Liver Function Test done which showed abnormal values (AST, ALT). To treat the itch I was prescribed Udiliv (300 mg), twice daily, followed by three times a day due to the level of skin irritability. At week 33, I went for an ultrasound merely out of curiosity and was told by the radiologist that the amniotic fluid as more than expected, the lag was of 3 weeks in addition to what was seen to be a distended abdomen. She asked me to immediately contact my Gynaecologist who then proceeded to do yet another ultrasound. This time around I was told that the ?stomach bubble? was nowhere to be seen but it could be due to the way the baby was placed. I was asked to return in a few days time during which the ultrasound showed the baby to be dead. The foetus was then removed and showed peeling of skin meaning that the child had died already 2 days or more prior to the C-section (my own choice). Also, the Gyn mentioned that the placenta was calcified (Fourth degree) but the placental investigation report showed it to be calcification of second. Additionally the baby was no more than 1.1 kilos at time of birth.
Questions that I wish to ask during my appointment with you:
1. What kind of Liver disorder did I have? Could it be Obstetric Cholestasis? If it was OC what are the chances of me ever having a normal pregnancy?
2. Was it aggravated or even caused by the use of Fertigyn and Susten?
3. Where can I read up on these two medications?
Yours,
Micky







Feb 20, 2011
Still born
by: Wray

Hi Micky Fertigyn is a trade name for human chorionic gonadotropin (hCG), see here. I fail to see why you were given this for a haematoma, see here. hCG is given if the corpus luteum is making insufficient progesterone to sustain the pregnancy. But you were also given Susten, which is progesterone, maybe they thought you were going to loose the baby, or being ultra cautious. Progesterone is generally sufficient, but the amount needs to be high, and it should always be reduced slowly. See our page on Pregnancy. It was almost undoubtedly cholestasis, see here, here, here, here and here. I've not heard of hCG causing cholestasis, and progesterone is protective, as it suppresses excess oestrogen. It's evident that excess oestrogen if not causes it, certainly exacerbates it, see here, here and here.. Drugs cause it too, see here, here and here. There's little info on Fertigyn itself, but plenty on hCG, see this one here. Likewise with Susten, it's made by Sun Pharma in India, see here. Please have a vitamin D test done, this is such a vital nutrient for both the liver, see here, and pregnancy, see here. For more info see the Vitamin D council website. Take care Wray


Feb 23, 2011
Susten 200
by: Anonymous

HI, I am 23 yrs old female, I had bleeding in my 6th week of pregnacy and after 2 weeks time it got spantaneously aborted. I was using susten 200 since from my 1st month of pregnancy? Why I had abortion, can any one suggest?

Mar 07, 2011
Susten 200
by: Wray

Hi there As I told Amit in the first query, Susten is a natural progesterone but there's little point in taking oral progesterone, as 80-90% is destroyed by the gut and liver as it passes through. Please see our page on Delivery systems for more info. You would have been getting little progesterone from the oral dose. It would have been better to have used it as a pessary in the vagina. The cap dissolves readily and you would have had the full benefit of the progesterone. It's always better to start the progesterone before you fall pregnant too, please see our page on Pregnancy for more info. Take care Wray

Mar 07, 2011
Fibroids and Pregnancy
by: Manjari

Hi Wray,
Last week I was diagnosed with 3 enlarged fibroids of 7/8 cm in size and few small ones of 5 cm and other multiple. Doctors had taken a decision to go for a surgery to remove them. I'm 29, no kids. Today my pregnancy test came positive. Doctors have said, now no surgery, continue with pregnancy. Please share complications that may arise.

Mar 10, 2011
Confused
by: Anonymous

Hi there Wray..u seem to have quite a bit knowledge about things here. I am pretty confused and depressed about my situation being pregnant 1st time. Right now at 7 weeks. My progesterone at week 6 was 6.2 which the doc said is quite low and suggested susten 300 for 14 days through vagina. I also got done an ultrasound sac which suggested that my embryo/egg/feotus is lying a little low than normal in the uterus. This is what is terrifying me. The doc says i have 50 50 chances of surviving the pregnancy. I have had spotting on and off since i missed my period. but very little only when i wipe, lets say once in 3-4 days. Plz share any knowledge about the position of the embryo..

Mar 17, 2011
Fibroids and Pregnancy
by: Wray

Hi Manjari Normally pregnancy and delivery proceed without a problem. Very rarely can they cause miscarriages, premature labour and bleeding. Fibroids are stimulated by excess oestrogen, so you evidently have too much. You might consider using progesterone, as this suppresses excess oestrogen, it would appear yours is too low. We do have a page on Fibroids, plus one on Pregnancy which you might like to read. Fibroids are an inflammatory disease, caused by oxidative stress. In all likelihood you have a vitamin D deficiency, this is a potent anti-inflammatory, plus it prevents cells proliferating, see here, here and here. Progesterone prevents cells proliferating too. Please have a vitamin D test done, for more info see the Vitamin D council and GrassrootsHealth websites. Vitamin D is vital for a developing foetus, please have that test done, and see these papers here, here, here, here, here and here. Take care Wray

Mar 18, 2011
Confused
by: Wray

Hi there I'm guessing he means you could possibly have placenta previa, But you would have to confirm this with him. There's more info about this on this excellent site here. But don't be terrified, unfortunately miscarriages are very common, about 25% of pregnancies end in miscarriage during the first 6 weeks. I had five before I had my daughter, all caused by extra stress at the time. Stress drops progesterone levels, if this drops too low, a miscarriage can occur. I'm pleased your doctor suggested the progesterone, and via the vaginal route too. Too often Susten is given orally which is not very effective. We do have a page on Pregnancy you might like to look through. Please have a vitamin D test done, this is so critical for a healthy pregnancy and child, see here, here, here, here, here and here. For more info on testing and vitamin D see the Vitamin D council and GrassrootsHealth websites. Take care Wray

Apr 05, 2011
Progesterone use
by: Anonymous

Hello,
I have an urgent question that I hope you can answer. I am about 10 and a half weeks pregnant and i ran out of Progonol progesterone cream. My order will come only in a few days at best. My question is this: will I have a miscariage if I don't use the cream for a few days? can I use another brand of cream meanwhile the new Prognol cream arrives? Please help me, I don't want to lose this baby.
Sincerely.

Apr 08, 2011
progesterone and ivf
by: Anonymous

Hi, I have done ivf and the result is positive, I have taken progesterone from the day after egg collection till today, that it exactly 2 weeks, I think I am 4 weeks pregnant now, I just got a positive result. At the clinic they told me to stop taking the progesterone because my body will carry over producing it. What happens if my body doesn't produce enough progesterone? I might loose the baby I guess. and why they are not giving me anything?

Apr 20, 2011
Progesterone use
by: Wray

Hi there I'm sorry I can't answer urgent questions, as I don't get to the query in time. There's no way I can tell if it's urgent until I've seen it. I do hope all is well, but yes you can use any progesterone cream. Always stick to the same amount you were using in a previous one. By that I don't mean the amount of cream but the amount of progesterone. We do have a page on Pregnancy you might like to read through. Take care Wray

Apr 20, 2011
progesterone and ivf
by: Wray

Hi there I'm a bit puzzled why they only gave you the progesterone for 2 weeks. It's normally given for longer when an IVF procedure is done. Once pregnant the ovaries continue making progesterone until about 8 weeks, when the placenta takes over. If you don't produce enough progesterone a miscarriage is likely, evidently they don't believe you will miscarry. Watch for any signs of a drop such as spotting, bleeding, headaches, water retention etc. If this should occur I suggest you do start using it again, it's best in a form which is absorbed well, not oral, as this is the least effective Delivery system. We do have a page on Pregnancy you might like to read through. Take care Wray

Apr 24, 2011
thretened miscarriage
by: Anonymous

Hi Wray,
I have one healthy two year old who I gave birth to in Mexico, and in my 6th week of pregnancy was diagnosed with low progesterone and put on supps. Since then I have moved back to the UK and had 2 miscarriages at 9 weeks. I have not been offered a progesterone test let alone meds as they do not believe it can prevent miscarriage here. I am now 5.5 weeks pregnant and bleeding. I managed to get hold of Lutinus 100mg from a doctor in Denmark who prescribes it for IVF patients. Should I start taking it now- I don't like to go "behind the back" of my UK doctor but am desperate to try anything to prevent a 3rd loss. Thanks for your advice.

Apr 25, 2011
Pregnancy test after IUI
by: Sashidhar

Hi, My wife is 35 yr old and her last LMP is 2nd Apr'11 (25 days cycle). We had done IUI on 14th Apr b?couz of low egg quality. Our Gync has advice her to take susten 300 vaginal twice for 15 days. Today is 12 day after IUI and some symptoms of backpain and tiredness. She was earlier diagnose with hypothyriod but now it is in control.

When do you suggest to take home pregnancy test?

Apr 29, 2011
Taking Susten 200mg twice a day
by: Dee

I am 24 weeks pregnant. I had a miscarriage before this one so, this time my doctor prescribed to take Susten 200mg twice a day. once in morning and night. I was also given HUCUG 5000 injection weekly once from my 5th week till 15th week.

I am taking the Susten 200mg tab from 5th week and my doctor has asked to continue till delivery.

I hear so many mixed opinions on this tablet's side effects. Please help me clear my doubt.

1. Is taking this tab twice a day till delivery harmful?
2. Will this affect my baby?
3. I am taking this tablet orally. Is this ok?

Thanks.

Apr 29, 2011
Progesterone question
by: Anonymous

Hi Wray, I am 14 weeks pregnant, and on the advice of my naturopath I have been using natural progesterone cream since before I got pregnant. My doctor (obgyn) doesn't seem to think I needed that at all, even though I had an early miscarriage in fall. I do have an older child that was born without any complications :) Since, I am 14 weeks, I have gradually started to decrease the dose of the cream again on the advice of my naturopath. My question is this: is it safe to decrease the dosage of the cream so that eventually I can stop using it, or should I continue to use it?

I could not get definitive answers to my questions from my naturopath, she told me that I can do as I feel. What are possible complications? What signs should I watch out for when I decrease the dose of progesterone cream?

Thank you sincerely.

May 02, 2011
Susten in 25th wk
by: Debbie

Hi! Thank you so much for your patient and very helpful replies!
I am in my 25th week and the doctor has prescribed Susten 200mg (due to shortening of the cervix I believe) to be inserted (not consumed orally). However I have read contraindications mentioning risks of hepatitis, etc. if Susten is taken in 2nd & 3rd trimester. Please can you advise if this is ok? Thanks a lot!

May 04, 2011
thretened miscarriage
by: W

Hi there It's very interesting you say you were given progesterone by Mexican doctors. A few years ago I corresponded with a woman from the States who was also in Mexico, she was given it successfully for the same reason. Why a so called 1st world country can't do the same beats me. There are countless studies showing progesterone does help prevent miscarriages. Particularly if they are recurrent, which is a good indication progesterone is the problem, and it's not genetic. We do have a page on Pregnancy you might like to look through. Normally the amount used is higher than 100mg/day, I suggest rather than take it, you open the capsule and rub it on. Oral progesterone is the least effective Delivery system. We do have a distributor in the UK who could get the cream to you quickly, if you wish to try it. I've helped numerous women throughout their entire pregnancy, to go on the have a baby. The cream is as effective as the more commonly used injections. The distributors web site is here. I do hope I'm not too late with the advice, I can't answer all the queries I get quickly enough. Take care Wray

May 04, 2011
Pregnancy test after IUI
by: W

Hi Sashidhar I really suggest you go back to your Gyn to have a test done. Home pregnancy test's are not very reliable in the early days. I also recommend using the progesterone for at least 3 months if there's the possibility of a miscarriage. We do have a page on Pregnancy you might like to read through. Take care Wray

May 04, 2011
Pregnancy test after IUI
by: Shashidhar

Thanks Wray,

As suggested by Gync my wife have stop Susten 300 after 15 days but unfortunately she got period after 2 days. Normally her cylce is for 25 days, don't whether she got period due to stop of progestrone or there was no fertilization during IUI process.

We will try 3rd IUI cycle and take advice from Gync whether we can take Susten 300 for 1-2 months after IUI and do pregnancy test after period is missed. What do you suggest?

Do Susten 300 (daily 2 vaginal) delay pregnancy for more than week? Please advise. Thanks.

May 11, 2011
Pregnancy test after IUI
by: Wray

Hi Shashidhar I suspect stopping the progesterone suddenly like that caused the period. It would be far safer to use it as you suggest, but for 2-3 months. The danger period is in the first 4 months, after that placental progesterone is usually sufficient to sustain the pregnancy. Much better to use the progesterone vaginally, the capsule should dissolve adequately. Alternatively open it and rub the oil on the skin. As it's very concentrated, it might be better to mix it with a natural cream or oil to thin it down, this will make it spread further on the skin. Once the period is missed a test would be advisable. I'm not sure that you mean by does Susten delay pregnancy. It will only delay it if your wife uses it daily before ovulation, as 300mg is more than sufficient to stop ovulation. If pregnancy is the aim, progesterone should only be used after ovulation. But as you are having IUI, the doctor will guide you. Please ask your wife to have a vitamin D test, this is so critical for the normal functioning of the ovaries, and for ovulation. It's also critical for a growing foetus, see here here, here, here, here and here. Take care Wray

May 13, 2011
No heartbeat on 5-6 week of fetus
by: Sheela

Hi Wray, I am 28 yr female, my last periods came on 13 march and just few days ago came to know I'm pregnant as earlier I had pcod and right fallopian tube blocked .this pregnancy is miracle for me even the dr says same on my first visit to dr he made me do usg of pelvis and result came no convincing heartbeat as m y dr had started medicines like susten 200 once in night through vagina and folic acid. Dr didn't said its serious he said we will wait more 10 days take medicines and than again go for sonography and see what happen and I don't have any spottings nor pain everything thing is fine but I'm worried about heartbeat of baby please help out. Thanks in advance.

May 13, 2011
Used Susten to delay Period but now in a confusion.
by: Shankar

Hi Wray,

Background: Am married for 2 years now. From this April 2011, wife and I thought of attempting for an offspring. No attempts were made before, hence no history of pregnancy and thus no history of miscarriage.

My wife had her last chums on April 10 (28 days cycle; regular). So we made 3 attempts between April 20 and April 30. But a family function got arranged on May 8 and my wife badly needed to attend it. Since it was a religious function, she shouldn't be in chums during that time. During the first week of May, we weren't sure if our attempts were any successful and she might miss her May periods. Wife went to a Gyno and told her that she wanted to postpone her periods but attempts were made for a baby as well. Doc gave her Oral dosage of Susten 200 for 3-4 days which was taken in the first week of May. Now she has missed her periods and a home pregnancy test yesterday turned positive.

Now we are concerned whether Susten taken during the initial days of her pregnancy have any bad effects on the baby being developed in her womb. Many articles on internet regarding an abnormal baby born because of progesterone dosage during pregnancy has added to our concerns. Please enlighten us.

May 14, 2011
Used Susten to delay Period but now in a confusion
by: Shashidhar

Thanks Wray for valuable suggestion

Jun 02, 2011
progesterone ?
by: brittany

I was told from an all natural doctor to take what is called Progon B. Has anyone ever taken this during a pregnancy or even before? What did it do for you and is it safe while pregnant?

Jun 29, 2011
Austen and fertigyn support
by: Abc

Hi I am 39 yrs old and succeeded a missed abortion in march when I was 9 weeks pregnant. I missed my period by a week (Lmp 21/05/2011 and tested positive to a pregnancy test. I had mild vaginal spotting on the 24 of june. My gynaec has put me on susten 200 vaginal tablet twice day and inj.fertigyn once a week. On a transvaginal scan my gynaec confirmed the sac in the uterus and also told me it is very small. I am worried whether this will lead to another miscarriage. Is bed rest compulsory and do I restrain myself from my regular activities such as cooking...?

Jul 05, 2011
progesterone and duphaston after iui
by: jan

Hello Wray, I had iui on 25th june i.e 14th day of my period with 29mm follicle. my doc said that my follicle released egg and suggested me progesterone 200mg twice daily for 15 days and duphastone 10mg for 10 days, this is my 3rd iui.

I am 30 years old and I have only left tube as in 2009 I got ectopic pregnency i.e my first pregnency. We started trying for pregnency from last 8 months.

I am having gastrable and my belly becomes big when I take this progesterone tabs and i feel drowsy.

My concern: what is my problem for conceiving and why this medications are suggested for me. With 29mm size follicle can have a good egg? Do I conceive. Please advise. Thanks.

Jul 29, 2011
IM FEEL FEAR
by: SRAVANTHI

HI,i am pregnant now 1 1/2.last day im getting some brownish colour bleeding is coming.my doctor give SUSTEN-200 MGtablet is given andMCBM-69 also she given.im continue this tablets or not.......

Aug 02, 2011
helo Wray .. concerned hubby
by: m

we are married for last 2 and 1/2 years and had been trying for last 3 menstrual cycles only for pregnancy. Hence no previous pregnancy or miscarriage; however we were desperate for conception. The menstrual cycles of my wife were irregular and last cycle lasted 35 days. A family friend and a leading gnac in our city prescribed Dufaston for first 10 days on day of follicle rupture. Now on 38 day of LMP we had an positive UPT . today on 40 day of LMP i.e about 6 weeks my wife noticed blood tinged mucus on urination. An ultrasound showed normal sac and confirmation of pregnancy.on this information our consulatant started on immediate 200mg susten(to be given twice for 2 weeks ) as vaginal suppositary and an stat shot of 5000 unit Hcg which was given immediately.The levels of progestrone or hcg were not tested

i am gravely concerned about the side effects of Hcg during pregnancy and would like to know evidence in support or against it.

What are the chances of Birth defect in an single shot of Hcg?

Can further damage be prevented??Does its benefits along with Susten outweigh the side effects? Was the doctor wrong in not informing us about the side effects?

Aug 02, 2011
hellpppppp,,,,,,,,,,,,,,
by: Anonymous

Married since last 2years but started planning for baby since last 3 Menstrual cycles only. After the Last MC my wife was advised to take Duphastone(syn progestrone ) 10mg for 10 days o.d after the day of rupture of follicle.On 38 day of LMP she had an poistive UPT and today on 40 day she had blood tinged mucus on urination( ??spotting ) We took urgent sonography which revealed an normal developing sac . Our Gnc consultant advised immediate single shot 5000 unit hcg injection and 200mg Susten Suppository twice daily for 2 weeks .having read the risks of Hcg kindly advise about the risk we took in taking Hcg ? whether the dose of single shoot hcg enough for an risk of damage?

Sep 07, 2011
Reply...
by: Anonymous

i was given as well 5000 unit hcg twice in a week time in my 8th week of pregnancy because of light bleeding. Since it is not allowed to be given in the USA, but it is commonly used in my country.

However, what made me a bit relaxed a comment about a women who took it twice a week and delivered a healthy baby.

Sep 17, 2011
Spotting on Prometrium
by: Frustrated

Hi Wray, I have a 2 year old and recently had a miscarriage on my second in April. Baby stopped developing at 8 weeks. Had to have a D&C. Waited until last month, August, to try again. Dr put me on promethium on the 8 th of this month right around ovulation. Just started spotting a bit this past Thurs. Is it normal to spot on promethium or could I be experiencing implantation/ miscarriage? Also, could a D&C affect future fertiity? Ever since the D&C I have brown spotting before my cycle and never had that before. Thanks

Sep 17, 2011
Progesterone in early normal pregnancy?
by: Anil

My Wife is 31 Yrs old and has a previous history of 2 Miscarriages.

She is now almost Five weeks pregnant,

My wife's doctor has advised her to take...

1.Sustan 200 Mg (suppository )daily
2.Duphaston 10 mg twice daily
3. HCG 2000 IV(Once in a week)
4. Sustan IV(Once in a week)

Can you please advise us?

Sep 22, 2011
44 days since last period
by: Maddy

I am married since 1 year and 2 mths. Within a year I had conceieved but was ectopic and it has been terminated by removing my right fallopian tube and my gyn told me try for pregnency after 7 mths. My gyn advised me to take susten 200 mg orally and 300 mg supositories since one month effective 22nd of august. My periods was regular and every month 10th was my LMP. Now I missed my periods and it has been 44 days. I tested 3 hpt was negative. I took HCG serum test on 17th of sep. it came <2.0. my gyn told me to stop susten from sep 20. Now yesterday I had brown spotting and after that I didn't. Today one spotted. Should I wait and do a blood test to know my pregnancy? I'm curiously waiting to know whether I'm conceived or not. pls advise...

Sep 25, 2011
Side-effects of Susten 200mg
by: Gupta

Hi Wray! I am 7-weeks pregnant and was advised to take Susten 200mg vaginally as the embryo was not growing as expected. Taking Susten 200mg has relived me of lower back pain and stomach cramping but I experience instant headaches and giddiness on taking the same. Is this expected behavior of this tab and can something be done about this? My gyne has suggested me to stop taking this altogether. Help!

Sep 26, 2011
44 days since last period
by: Maddy

Hi Wray ! my periods lasts for 45 days and was continuously taking susten 200 orally and 300 mg internaly. but my gyn told me to stop taking the tablet and now i have got my periods. but it lasts for only one day. that a very medium flow. so is there chances of getting pregnant in my next cycle. my doctore told me to take susten on 15th day to 28th day after periods. Will it helps me to get conceive? I'm very anxious to know ! pls advise....

Oct 02, 2011
happy..but worried too
by: Anonymous

I'm 9 weeks pregnant..had i missed abortion in sept 2009 and a spontaneous miscarriage in april 2010. tests indicated a high blood coagulation n i was put on ecosprin 75mg.now 9 weekpregnant with the second baby i have been put on susten 200. 2daily n a weekly hormonal injection + ecosprin and since my TSH was recorded 7.5 i m also taking a daily morning dose of thyroxine. things seem to be fine. though i hav a very horrible taste an am ating very less the frequent vomiting i felt during my last pregnancy is missing. i vomit day and may be fine for the next few days..hope every thing is fine. my first sonography was done on 6.4 weeks and the regular heartbeat was recorded.

Oct 12, 2011
Susten-200 till when
by: Anonymous

I am 10 weeks pregnant. This is my first pregnancy. I have had spotting 3 times (5th week, 8th wee, 9th week) till now (it was brown colored with few bright red spots/kind of clot).

Because of this 3 ultrasounds were done which showed the baby & heart beat too.

I am now on Susten-200 twice a day (morning & night as VT). No blood test has been done to check progesterone level. Need to know till which week should I continue it.


Nov 08, 2011
Sustene 300
by: Meenakshi

Hi Wray, My periods has been irregular and delayed every month by 1 week or 10 days each month. I am maaried for more than two years now and planning a baby. My LMP date is 29th September. My Gyn had conducted Follicle monitoring which shows problem of PCOS and then injected HuCog (I dont remember either it was 5000 or 10000). We had IUI on 19th Oct 2011. I was given Duphaston for 10days twice a day. Later, My Gyn suggested for Beta HCG test which was 37 at first time and increased to 256 within 3-4 days which means confirmed pregnancy. I am also suffering from hypothyriod which is controlled with medicine. Now, my gyn has advised me to take Sustene 300mg tablet twice a day for 6 weeks. Please adise if taking progstrone in this form is harmful? Also, does "oral prgesteone" means taking progesterone as tablet?

Nov 08, 2011
Lutinus?
by: Anonymous

I've had 4 miscarriages and my doctor recently perscribe Lutinus to me. I haven't started taking it yet, cause he wants me to start tomorrow....but I'm a little scared because the pamphlet says it could cause blood clots...is this true? like is it that dangerous?

Nov 12, 2011
can there be too much?
by: Anonymous

I'm currently 6wks 1d and have been taking prometrium 200mg x2 since 4wks 4 d. i started having a dark brown discharge a few days later. it is getting heavier and think it maybe from these meds. my dr didn't seem concerned because it's brown "old blood" and not red. but this doesn't have me convenced. Am i bleeding because this drug is not needed or too much?

Dec 01, 2011
hoping against hope
by: anonymous

Hi Wray.....i did an iui on the 16th and 17th of november and have been on susten suppository since then.....today on 1st December i have spotting while still on susten. Is this my periods?

Dec 03, 2011
am 5 week 6days preg
by: farhana

Hi sir,my last date was 23 Oct ,3rd week of pregnancy I knew it.from 6th week of 5day am spotting brown color n doctor adviced to take susten 200 mg oral from 2day I strated daily one will u plz advice me why its spooting I Snyder want to loss my baby ,


Dec 10, 2011
If use of susten there is no defect on normal delivery
by: vvs

My family doctor is suggested to use susten 200 tablets daily for my wife.My friends told that if she use that tablet the chance of normal delivery is less. Pl clarify for me.

Jan 15, 2012
Please suggest
by: Dibbendu

My wife is 7 weeks pregnant and today we went for USG . The report says MISSED ABORTION and No heart beats found .
We consulted the doctor and advised us to use Susten 200 for 5 days and then do the next USG after 10 days . We also consulted another doctor and she suggested to inkjet Corian 5000
We are totally confused , what should we do
please suggest

Jan 16, 2012
MISSED ABORTION
by: NISHA

I AM 7 WEEKS PREGNENT WHEN SONOGRAPHY TEST SHOWS HAMORRAGE IN UTRUS, GIVEN DOSES ON C HOP 200 TWICE A DAY AND PROLUTON 500 MG INJ ONCE A WEEK, TO CONTINUE TILL 4 WEEKS. AFTER 4TH WEEK SONOGRAPHY SHOWED MISSED ABORTION.
CAN THESE MEDICATION CAUSE MISSED ABORTION?
KINDLY ADVICE...

Jan 18, 2012
Progesterone cream use..
by: Anonymous

In the last 3 years I have had 4 early miscarriages all as a result of low progesterone> My OB/GYN wants to do blood draws at the time of positive pregnancy results to check my levels and by that time they have started to drop. She wont prescribe them in the meantime so i can take them. Here is my question I recently found out i was pregnant just yesterday and after numerous calls to my doc she cant see me till the end of next week so I decided to take matters into my own hands and bought some OTC progesterone cream from a local store. Am I going about this wrong and is it to late to start using the cream since i already tested positive for pregnancy? I am looking into a new doc but in the meantime I am at a loss on what to do. It's almost like she waits to long and I am already in the process of miscarrying. This will be my 5th pregnancy without any live births and I am at my wits ends. Where do I go from here? The cream is a GNC brand and says it has 5mg per ounce. Should I use now or wait for the enevitable to happen and try again using the cream from the start of ovulation??? Please help

Jan 20, 2012
break in taking Lutinus in early pregnancy
by: Dorothea

Hi Wray, Thanks for this site and all the info. So far i didnt come accross a matter that is my concern at the moment. I had 4 miscarriages in total, 2 early ones, both at 5 weeks, one at 10 weeks with D&C, one healthy natural unsupported pregnancy and healthy child. Had one miscarriage before my daughter at 7 weeks. Now i am 6weeks pregnant and 2 days after conception i started to take prescribed Lutinus, was taking it for 6 days but it was giving me side effects, feeling depressed and dizzy so i stopped not being sure that i was pregnant. When the test came out positive i started to take it again. So i had break in taking lutinus for 10 days. How could this affect the pregnancy? So far all seems normal, no sickness though, no extreme pregnancy symptoms. Thanks in advance for some answers

Jan 24, 2012
udilive 300
by: Ajay

Dr advise my wife to take udilive 300 3 times a day..on 38th week which is most warst thing i had ever done becoz i lost my baby just ater 24 hrs..

Jan 30, 2012
Susten 200...!!
by: Anonymous

HI,
Im on my 5 weeks of pregnancy i had a miscarriage before 8 months, now doctor has suggested me susten 200 to be kept in the vagina..but im confused..if im using the tablet im able to spot out some white patches in my pantie in the morining. my doubt is does this hapens to all or am i using the tablet in a wrong sense..PLS HELP ME..!!

Jan 30, 2012
Its ok
by: Sheela

Dont worry Sister .its common.But still you have dout pls discuss with your Gynaec.

Feb 02, 2012
Duphaston 10 mg -3 times a day?
by: Anonymous

Hi there,

I miscarried my first pregnancy @ 8-9 weeks due to irregular sac spotted in 6.5 weeks early scan. I opt nature to take its course.

Since there is no spcial medication or suggestions are given in NHS-UK. I got everything checked before ttc this time.

Doctor back home in india has suggested me duphaston 10 mg 3 times a day as a precaution this time.

Now I am 5+ weeks pregnant and worried if duphaston is going to affect my pregancy or baby ..or its just safe to continue taking the dose doctor recommended.

Unfortunately there is nothing we could do in UK till I am 8 weeks and go for my first midwife appointment which is nothing but routine check up.

What would you suggest if in my situation? So far, I face no spotting.. but not morning sickness either.

Feb 03, 2012
How and when to use progesterone cream in early pregnancy
by: Anonymous

I am almost 6 week pregnant. This is my first pregnancy. Me and my husband worked on it almost 2 years. I had very short menstrual cikles (21-24 days), heavy and long bleeding and strong PMS simptoms. For 5 month before pregnancy occur I have been taking homeopathic medicine with Vitex agnus castus and went to reflexology terapy. After 3 menstrual cycles it was successful.
Now I have some cramping and pain in lower abdomen, some nausea, I have sensitive and painful breasts, I am tired at day time but at night I can not sleep. My vaginal yeast infection has worsen. As I understand these are normal signs of hormone fluctuation during pregnancy. I am concerned about my progesterone level (before pregnancy it was my serum level 12ng/ml on 21th day of the cycle), so I went to examine my blood these week and received these values: S-Progesteron: 36,74 ng/ml, S-Estradiol: 396,3 pg/ml, beta HCG: 11654 mIU/ml, S-cortizol (in the morning): 330,7 mmol/l.
Do you think these are noraml values and I not need to be worried about? I have 1 tube of your Natro cream (33,33 mg progesterone/g) at home just in case if some vaginal bleeding would occur. Do you think it would be effective for that problem and how much should I use in that case?
If I start using it and than problems stop, how should I lower the doseage of cream that the change would not be so sudden? Thank you very much for your answer. Best regards, Maja.

Feb 10, 2012
Is progesterone safe during pregnancy?
by: Anonymous

Hi Wray. I am 6 weeks and 3 days pregnant. Two days ago my basal body temperature droped a little bit (from 98,6 to 96,8). I thought that this was due to the decrease of progesterone so I start using ¼ of teaspoon of your cream twice a day. I think that I am a little bit calmer after I take it. But than I asked gynecologist about use of bioidentical progesteron cream in pregnancy and she said that is not safe. She said that the only safe form is natural micronised bioidentical progesteron that is prescribed by OB. Now I am scared that I am doing harm to my baby. Is it safe to use Natpro cream during pregnancy?
I have one more question: If I wont to stop using the cream for how much should I reduce the amount of this cream that I do not cause hormone fluctuation?
Thank you very much for your answer.

Feb 21, 2012
PLEASE HELP!
by: AnonymousAR

I had three miscarriages. I'm 5 weeks pregnancy and my gyn prescribed progesterone 200mg x 2 (vaginal) everyday. My question is it ok to continue with sex?

Feb 23, 2012
progestrone for irregular periods
by: mini

my doc has prescribed me susten 200 fr 10 days twice a day.but i feel vertigo and dizziness aftr taking it.secondly m nt aiming at getting pregnent yet..she has prescribed it for my irregular periods.is it ok??

Feb 25, 2012
Is progesterone safe during pregnancy?
by: Wray

Hi there Progesterone does calm us, as it activates the GABA receptor sites. GABA is one of the most calming neurotransmitters. Progesterone is progesterone no matter what form it comes in, so of course it's safe! There are many Delivery systems, the best being injections, suppositories or creams. If you search around the site, you'll notice many women have used the cream successfully during their pregnancy. It is always best to reduce slowly, pregnant or not. I suggest 16mg each reduction which is 1/2 ml of cream, and to stay on this a few days before reducing further. We do have more info on our Pregnancy page. Take care Wray

Feb 25, 2012
PLEASE HELP!
by: Wray

Hi there Yes is safe to continue having sex. If concerned ask your gyn too. Take care Wray

Feb 25, 2012
progestrone for irregular periods
by: Wray

Hi there Your doctor should have warned you about Oestrogen Dominance. Please read through this page as it explains why it happens. And we do have more info on our page How to use progesterone cream Take care Wray

Feb 28, 2012
Miscarriage
by: Abhishek

Hi there,

At about 9 months back my wife was pregnant & after 7 weeks bleeding started & there was a miscarriage.

Now again she is Pregnant & 6 weeks are completed yesterday. Still she is feeling strong pain in pelvis as she feels during start of her monthly periods. Also there is occasional stomach / abdominal pain. Although there is no spotting detected. Doctor has started HCG 5000 injection weekly, Duphostan twice a day & Gestofit 300 once a day.

What can be the reason of this pelvis pain? Is this normal? Is there any danger for this pregnancy also? Is the dosage of medicines are normal? Any side effects? Please reply.

Feb 28, 2012
Miscarriage
by: Wray

Hi Abhishek I always suggest beginning progesterone well before conception, we do have more info on our Pregnancy page. Duphaston contains dydrogesterone, a synthetic progestin, see here. Gestofit is progesterone, I see no point in giving the Duphaston too, apart from the fact it's synthetic. I don't know what the pelvic pain is caused by, although it looks likely it's an increase in prostaglandins. These cause uterine contractions. I hope the Gestofit has been given in time, as it could save the pregnancy. hCG is often given to stimulate the corpus luteum to produce more progesterone, I hope this helps too. There are no adverse side effects from the progesterone or hCG, apparently none from the Duphaston. But because it's a progestin, it's not broken down into the normal progesterone metabolites, these are as important as progesterone itself. For more info on progestins see here.
(Scroll down to the second link on Google to see the full pdf article). There is a section on dydrogesterone. Take care Wray

Mar 09, 2012
How to use Progesterone
by: Anonymous

Hi.... I'm 3 weeks pregnant, my doctor advised me to use Progesterone capsules (Gestofit) 200 mg. I read it is advisable to use it at vaginal rather than oral. But i am not aware how to use exactly at vagina. Could you please advise me on the intructions.

Mar 11, 2012
How to use Progesterone
by: Wray

Hi there All you have to do is insert the capsules into your vagina. Your doctor should have explained this to you. Take care Wray

Mar 13, 2012
5th week of pregnancy.
by: Anonymous

Hi Wray my wife did the urine test and it came positive so she went to see her doctor whod asked her to get the ultrasound done.The report says that foetal pole is not detected or identified the size detected was of 7mm and the duration of pregnancy was 5th week and 0 days as per the report. so her doctor asked her to come for the check up again and said he is afraid she could survive with this pregnancy and also said there are 90% chances of miscarriage. so we went to see another doctor and he suggested to come after 3 days as he was unable to detect the foetal pole and the heartbeat.and prescribed susten 200mg through vaginal route for three days

Few details
1)My wife's LMP 1st day was :-29th Jan 2012.
2)in the report it says 5th week and 0 days
3)but doctor said that its of 6 weeks now
4)during first 5 weeks my wife had Meftal Spas and Crocin as well



My questions are
1)her doctor did not tell her why he is sensing the 90% chance of miscarriage ?
2)When will the foetal pole detected and if it is detected late what are the effects of the same?
3)Why the dates are contradicting to the report?
4)are there any adverse effects of these drugs which my wife has taken during first 5 weeks.
5)and what are the chances that my baby will complete the regular pregnancy period and be a normal and a healthy baby.

Also i really appreciate your efforts to explain things to people about Progesterone and your article and responses are really helpful.

Thanks in advance.
Rohit

Mar 14, 2012
5th week of pregnancy.
by: Wray

Hi Rohit He probably thought the miscarriage likely because he couldn't detect the foetal pole. Although it's not normally detected until 6 or 6 and half weeks. Often it can't be detected until 9 weeks. The same applies to the heart beat, which is normally only detected when the foetal pole is. So it all seems too soon to give an opinion on a possible miscarriage. Why your doc and the report differ I don't know. How long is your wife's cycle, as this has a bearing on it. For instance if it's 35 days long, it would mean she is now only 3 weeks, 3 days pregnant. If it's 28 days long she's now 4 weeks, 3 days pregnant, and if it's 21 days long she's now 5 weeks, 3 days pregnant. For more info on the Menstruation Cycle please read through this page. I don't understand why she's been given the Meftal Spas, as it's used in the treatment of functional bowel disorders, and as an analgesic. Does she have irritable bowel? Or menstrual pain? It's not known whether it's harmful to the foetus, see here. And Crocin is paracetamol. It seems she has inflammation or pain of some sort? Please have a vitamin D test done, it's a potent anti-inflammatory and analgesic. So is progesterone. A lack of vitamin D is implicated in miscarriages, see here, here and here. As is progesterone, we have more info on our Pregnancy page. 3 days of progesterone, ie susten, is worse than useless. You'll see why on the link I've given you. A lack of vitamin D reduces the benefits of progesterone, plus it's vital for a successful pregnancy and the growth of the foetus, see here, here, here, here, here and here. Continued below.

Mar 14, 2012
5th week of pregnancy Part 2
by: Wray

Hi Rohit This is another paper here. These are excellent videos to watch too, see here and here. For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Another nutrient she could consider taking is taurine, it's vital for the growth of the foetus too, see here, here and here. I suggest about 1000-2000mg/day. Continued below.

Mar 14, 2012
5th week of pregnancy Part 3
by: Wray

Hi Rohit Taurine is not found in vegetables, nuts or seeds, only animal protein. Many people in India are vegetarians, and therefore lack both taurine and B12. Interestingly two major studies have been conducted, one in Pune, the other in Mysore, see here and here. In both it was found that insulin resistance was very common, and the risk for diabetes higher. The Mysore study found a shockingly high proportion of women with low vitamin D levels. This is now a known risk factor for IR, diabetes and heart disease in the offspring. The Pune study found high folate, low B12 a risk factor. Although I feel if they'd checked the vitamin D level, I feel this would have been the cause, or certainly a factor. Neither checked taurine levels, I also feel this would have been found low, and therefore a further risk factor. Please have a vitamin D test done! Bless you for the kind words! Sometimes the answer to a problem can be so simple, but rarely are levels of vitamin D, progesterone, and other nutrients checked. Drugs are always resorted to, with unknown consequences, and of course they only treat the symptom, not the cause. If your wife does have inflammation, it suggests a very low level of vitamin D, taurine, it's a potent antioxidant too, and progesterone. Take care Wray

Mar 17, 2012
5th week of pregnancy.
by: Rohit

Hi Wray,

Thank you for your prompt reply that will be really a helpful one but in the future not now as my wife had a miscarriage couple of days ago as doctor said that there was no growth of the baby the size measured was still 7mm and said that the baby is dead inside so its no point to continue with the same and asked to take some medicine (now do not remember the name) to terminate the pregnancy. He also has advised her to come back after a weeks time to do the TORCH test now i am trying to get more info on the same.

Things which i was not able to understand
1)the foetus size which doctor determined after ultrasound was 7mm and when he asked her to come back after 3 days the size was the same so was that normal or abnormal

2)her doctor also made a point that there may be thousands of reasons that the baby is dead inside so cant really determine one but after torch test he may be able to find one

3)My wifes Periods are not of exact lengh always sometime she had periods on 28th day sometimes on 40th day as well

4)Whenever she had delayed periods she experiences heavy discharge with the lower back pain so the reason she was kind of addicted to Meftal Spas

5)Being a Pharmacist i asked to stop those medicines but you know whatever you are it wont work inside your house

6)and also need your advise so that the same thing should not happen again in the future.

Thanks a ton once again Wray.......you are doing a wonderful job.

Mar 20, 2012
5th week of pregnancy
by: Wray

Hi Rohit I'm sorry to hear of this. Please don't let your wife get discouraged by it, unfortunately miscarriages are very common, I had five before having my daughter. Firstly the TORCH test, it seems this doctor is not in favour of it! His reasoning valid too. To answer your questions, it seems the foetus was already dead when he did the ultrasound. This would account for no foetal pole, no heart beat (although I think it was a bit early for these) and no growth from then until the miscarriage. There are many reasons for the death and miscarriage. One of the commonest is lack of progesterone, or progesterone dropping due to stress. This last was the case with me. Progesterone is vital for implantation, and ensuring there's sufficient blood supply to the foetus. If the blood supply fails the foetus will die. The other of course is lack of vitamin D. The huge swing in your wife's cycle makes me suspect PCOS, has she ever been checked for this? Please read through the symptoms and see if she has any. If she does it might be an idea to have a scan done on her ovaries. Now I understand the anti-inflammatory. Progesterone is such a good analgesic, please get her to rub the cream all over her lower back when she gets pain. In fact if she should consider using it, I feel she should use it daily for 2-3 months. This will ensure progesterone becomes dominant, and excess oestrogen is suppressed. Then once she feels stable she can begin to follow her cycle again, it is possible to regulate it with progesterone. We have more info on our page How to use progesterone cream. I would also suggest she tries N-acetyl cysteine too. This amino acid inhibits the MMPs which cause heavy bleeding. You might like to read this comment here The page on Menstruation explains the MMPs. I so appreciate your interest in helping your wife naturally, pharmacists normally only deal in drugs. Or do you also incorporate the nutrients in your business too? I've found them remarkable healers, in particular the amino acids. Plus of course progesterone and vitamin D. So from here…..I would ask you to get a vitamin D test done first, to read that page on PCOS to see if it throws any light on your wife's cycles, to start her on progesterone before she falls pregnant, to take the cysteine for the heavy bleeding and incorporate more animal protein, certainly add taurine if you don't eat it. She needs to heal before falling pregnant again. Thanks so much for the kind words and do let me know how you get on. Take care Wray

Mar 25, 2012
5th week of pregnancy.
by: Anonymous

Hi Wray,

I am so thankful to you for your kind reply with loads of helpful information. yes her doctor has taken her blood sample for the TORCH test has advised her complete bed rest for next 15 days starting last week. also he said she may need to use progesterone externally like u suggested but it all depends up on the test results which are yet to come hopefully we will get that soon. and yes my wife is not really discouraged after all this because we have adopted a baby girl who will become two come this june so she is taking care of her and happy with her. Although she was counting on our first baby but unfortunately things dint work as we wanted.
hoping for the best results possible in the future and am also going to ask my wife to join this blog as its really helpful and she will be able to get the important information.
Thanks a ton again Wray you are doing a fantastic job to encourage people like me and spread more information which others cant do.......

god bless u..........

Thanks and regards
Rohit

Mar 29, 2012
5th week of pregnancy
by: Wray

Hi Rohit Bless you for the kind words! I'm pleased the doctor suggested bed rest, the best form of medicine. I'm also pleased she's not too unhappy about the outcome, and has a little one to keep her company. Please don't let the results of the TORCH test concern you, judging by what that doctor said, it's not a very conclusive test. I wish you all the best for a possible second pregnancy, but please have that vitamin D test done! Take care Wray

Mar 29, 2012
400 mg progestron
by: Anonymous

hi,
in my 7th week, a v small blood clot was detected in my uterus . My dr. has put me on a 400 mg dose of susten VT till 12 weeks. Is this dose to high, i am extremly nauseous & have a terrible metallic taste.
in my 11 week now, last week for 2-3 days, i reduced my dose to 200 mg daily & was relatively better. is this a con-incidence ? I am back to 400 mg now.

Mar 31, 2012
400 mg progestron
by: Wray

Hi there You are suffering through Oestrogen Dominance symptoms. This is the reason I always recommend starting progesterone before pregnancy. It meant your progesterone level was low, if high you would not have had the clot as it helps prevent them, see here and here. It's ironic it does get better when reducing the amount, but it's only because it's now no longer stimulating oestrogen. I recommend increasing the amount if this should ever occur. I'm pleased you're back to the 400mg/day. We do have a page on Pregnancy you could look through. 400mg/day is not too high, may women are given 600mg/day and more. Take care Wray

Apr 02, 2012
susten 200
by: Anonymous

I am mother of 2 yr old baby and trying for another.
Today, I was prescribed to take susten 200 daily night for 5 days when I approached my gyna to postpone my menstrual cycle for 6 days till 9th Apr. Actually, my last cycle should be on 28th Mar.
While I google it, I found that susten 200 is used in pregnancy. I am confused why it was prescribed for me to postpone my menstrual cycle.

Can you help me to understand.

Apr 02, 2012
Will sustain injection delay periods
by: Janet

Hi wray, you have been doing a wonderful job.
I'm 28 years old had iui on day 16 & 17. Had hmg injections with clomid and bcc shot on day 15. Three follicles with good size. DH has no sperm problems. I had been put on susten
200 mg vaginal and susten injection 200 mg biweekly
I had missed my periods by 5 days. No symptoms
Of AF.. Scared to do a Hpt as I don't want to get
Disappointed. Previous two months I was on oral susten 200 mg but AF was on time... We r ttc for past 3 months.. Please help me by answering this...

Apr 02, 2012
400 mg progestron
by: Anonymous

Thanx Wray, for the frank opinion & guidance.

Apr 04, 2012
sustan VT
by: Raul

Hi Wray!!
My wife is 6 week pregnant now, as per her Gyno
she is advised to take progesterone tablets sustan VT 200 Mg twice in vagina.

Now as per her previous medical history she has enlarged uterus and hormonal imbalance due to which she also has unwanted hair on chin and upper lips,she was advised prior to her pregnancy
to take aldactone and glyciphage.

she stopped that medicine last november 2011 and now when she is pregnant i have few questions in my mind,i would really appriciate for your reply!!

1.will she be fine with her pregnancy period
2.do we have any danger of miscarriage(till now she is having no symtoms like spotting or cramps)

she is advised to get an ultrasound next week along with many test like Hmg,hplc,aborh,urine r/m,urine c/s,giu(r)rubella,tsh,hb18a,vdrl,hiv.

i am very confused by the fact why did her gyno asked for so many test.
For which i could guess few reason one of which may be baby develpoment inside body any genetical adverse effect which may be come or brain development of baby in this crusial period.

I hope i am clear to what essential for you may be to diagnose the case.

Thanks in advance for your kind help!!

Rgds
Raul


Apr 06, 2012
sustan VT
by: Wray

Hi Raul I can't tell if she will be fine, no one can. But she is on a very good amount of progesterone, so a miscarriage is unlikely. I have no idea why her doctor ordered so many tests, it seems like overkill to me. It's possibly due to the hormonal imbalance she had prior to pregnancy. It seems her testosterone level was too high, and her blood glucose unstable. This is so easy to treat with natural substances, but it's typical to give the aldactone and glyciphage. Possibly she has PCOS? Although you don't mention it. I've noticed in India they do seem to go in for a great deal of testing, but leave out the most important, and that's vitamin D. Please ask them to do this. It's so critical for a successful pregnancy, and in particular the growth of the child, see here, here, here, here, here, here, here and here. These are excellent videos to watch too, see here and here.
Even as far back as 1947 10,000-20,000iu's were suggested, see here. Plus these two here and here. Continued below.

Apr 06, 2012
sustan VT Part 2
by: Wray

Hi Raul If you're vegetarians, as so many are in India, please consider her taking taurine. This is only found in animal protein, and is also critical for the growth of the foetus, see here, here and here. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

Apr 17, 2012
Is it safe to use Duphaston?
by: Anonymous

i'm currently 8 weeks pg and my doctor prescribed the Duphaston. I googled it and read that it was not safe to use while pg... what do you think? Should I stop taking it and ask for another brand?

Apr 17, 2012
Is it safe to use Duphaston?
by: Anonymous

Hi Wray
Iam 9th of pregnant now and this is my first pregnancy.From 4th wk my Doc adviced to take Progesterone 200 mg till 8th wk.After 8 wks i went to check up..Baby hear beat is fine.Again my doctor adviced me take Duphaston 10 mg twice daily for 1 month.Is it safe to use ?
Please Advice.

Apr 17, 2012
Is it safe to use Duphaston?
by: Wray

Hi there Duphaston is not something I would recommend. It contains dydrogesterone, a synthetic progestin. But because it's a progestin, it's not broken down into the normal progesterone metabolites. This is something which is never taken into account by doctors prescribing progestins. The metabolites are as important as progesterone itself. In particular allopregnanolone, a potent analgesic, anti-inflammatory and anxiolytic. For more info on progestins see here.
(Scroll down to the second link on Google to see the full pdf article entitled "Classification and pharmacology of progestins"). There is a section on dydrogesterone. We do have a page on Pregnancy which explains the role progesterone plays, and how to use it too. There's more info here. Another progestin they might offer is 17 OHP caproate (17-OHP C), often given for pregnancy problems. I would always favour the use of progesterone. There is no evidence to date of any adverse side effects to the foetus while using progesterone during pregnancy, and it's more potent that 17-OHP-C, which also has safety concerns about it's use, see here and here. I can never understand why they don't just stick with progesterone, it's cheap and readily available. But more importantly there's no risk to the foetus. Take care Wray

Apr 23, 2012
Suggest Me
by: Anonymous

I'm 5 weeks pg... my doc prescribed me Progo-200, Duphaston and Folizorb. Are these drugs safe to use...

Apr 23, 2012
Suggest Me
by: Wray

Hi there I'm not sure what Progo-200 is, unless it's progesterone. Does it come in caps to take orally or as a vaginal suppository? It's best to use it as a suppository, as you loose most of it if oral, this is not the best Delivery system. Duphaston contains dydrogesterone, a synthetic progestin. But because it's a progestin, it's not broken down into the normal progesterone metabolites. This is something which is never taken into account by doctors prescribing progestins. The metabolites are as important as progesterone itself. In particular allopregnanolone, a potent analgesic, anti-inflammatory and anxiolytic. For more info on progestins see here.
(Scroll down to the second link on Google to see the full pdf article entitled "Classification and pharmacology of progestins"). There is a section on dydrogesterone. I can't find any info about Folizorb either, so can't comment. We do have a page on Pregnancy which explains how to use progesterone. Take care Wray

May 28, 2012
Susten tablet in use pragnacy
by: Rajnish from jammu

My wife is prgnt in 8 week . And his given to susten 200 tab .

Jul 09, 2012
Duphastone and Susten 300
by: Anonymous

Hi Wray, your comments have been most enlightening. thank you for your effort. Will you please help me in one regard? Susten is a progesterone as I can see. I am three week pregnant and am on Duphastone 10 mg thrice daily as well as Susten 300 because of some abdominal cramps and sustained abdominal pain. I am overweight, have high TSH levels and history of PCOD. if it safe to take both these medicines together? please advise.

Jul 10, 2012
Chorio decidual hemorrhage
by: Jan

Hi wray,
Pls help me by answering my query. I'm currently 13 weeks pregnant. I had two episodes of watery blood with lemon size clots. Scan showed baby as normal with correct growth, heart beat and fetal movement . However, the report said low lying anterior placenta and an area of chorio decidual hemorrhage
(5ccs). Dr has advised me on susten 200 mg twice and
HCG along with necessary vitamins . I'm on complete bed rest. I didn't sufficient info from my care taker or anywhere.
It's pretty scary for me as I have conceived after 2 years( had missed abortion). What are my chances of carrying this pregnancy to full term . Can you please let me know abt this?
-jan

Jul 11, 2012
Duphastone and Susten 300
by: Wray

Hi there Thanks for the kind words. Duphaston is a synthetic progesterone, i.e. a progestin. It's not something I would recommend, but doctors seem to use it for some reason. Duphaston contains dydrogesterone, a synthetic progestin. But because it's a progestin, it's not broken down into the normal progesterone metabolites. This is something which is never taken into account by doctors prescribing progestins. The metabolites are as important as progesterone itself. In particular allopregnanolone, a potent analgesic, anti-inflammatory and anxiolytic. For more info on progestins see here.
(Scroll down to the second link on Google to see the full pdf article entitled "Classification and pharmacology of progestins"). There is a section on dydrogesterone. If you are overweight and have a history of PCOS, then you are most probably deficient in vitamin D. Please have a test done. Vitamin D is vital for every cell to function normally, vital too for pregnancy and the health of the child, see here, here, here, here, here, here, here and here. These are excellent videos to watch too, see here and here.
Continued below.

Jul 11, 2012
Duphastone and Susten 300
by: Wray

Hi there Even as far back as 1947 10,000-20,000iu's were suggested, see here. Essential if you are overweight, see here, here, here, here, here, here and here. It's also vital for the thyroid too, see here, here and here. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. We also have a page on Pregnancy you could look through. Take care Wray

Jul 12, 2012
Chorio decidual hemorrhage
by: Wray

Hi Jan Apparently there is no known therapeutic intervention for chorionic hemorrhages. But you're doing everything you can to control the pregnancy, so I would hope it proceeds normally. When you say 'susten 200mg twice', do you mean twice a day, i.e. 400mg/day? If so this is excellent. The hCG encourages the corpus luteum to produce progesterone too. The bed rest will help, as any stress drops progesterone levels which can cause a miscarriage. I had five miscarriages, all due to stress. We do have a page on Pregnancy and another here. Please read through them to get an idea of progesterone's role during pregnancy. Take care Wray

Jul 12, 2012
Duphastone and Susten 300
by: Anonymous

Hello Wray,
Thank you so very much, I was totally unaware about this Vitamin deficiency! will get the tests done right away. Can't thank you enough.

Jul 13, 2012
Duphastone and Susten 300
by: Wrayy

Hi there So pleased the info helped. Please let me know the results of the vitamin D test, I'm most intrigued to find if it is low. Please make sure you get the actual results, and are not told over the phone that your level is 'adequate'! Take care Wray

Jul 30, 2012
LUTINUS -another 4 days?
by: Anonymous

Hello,
I'm taking Lutinus 1/day for 4 weeks now and the last one should be in another 4 days. I'm pregnant in 9 weeks and 1 day. My doctor is out of the country and I don't know who else to ask if I must continue with Lutinus add or I should just stop! I have had this year another pregnancy that ended up 11 weeks.
Thank you

Jul 31, 2012
LUTINUS -another 4 days?
by: Wray

Hi there I would always advise using progesterone for at least 3 months if someone has had a previous miscarriage. And to never stop it cold turkey. We do have a page on Pregnancy you can look through. Is it possible to get more? Otherwise you can order a cream over the internet, some shops also stock them. They are just as effective as suppositories. Take care Wray

Aug 18, 2012
oral progesterone
by: NewToThis

Hi Wray,

I am 8 weeks pregnant & had light pinkish spotting two days ago. Doctor said i have cervical polyp, and put a brown liquid med on it yesterday, hoping it dies & stump falls out. I bled heavily last night. Is that normal?

Doc gave me 5 vaginal suppositories for the polyp to use for 10 days every other night. Doc also gave me ORAL progesterone. I am not comfortable with oral progesterone because I read that it shld only be given if benefit outweighs risks.

First: is the vaginal supp for the polyp safe when i'm 8weeks pregnant? Second: Can I not take the ORAl progesterone, and use a vaginal progesterone instead, once im finished with my vaginal supp Polyp medication?

Aug 21, 2012
oral progesterone
by: Wray

Hi there I'm puzzled you bled heavily, I've no idea if the med for the polyp would do this, it's best you ask your doctor. Oral progesterone is the least effect Delivery system, as most is destroyed by the gut and liver. If he's concerned about the meds he's given you causing a miscarriage, injections, suppositories or creams are the best systems. And the amounts range between 200-600mg/day. We do have more info on our Pregnancy page. I don't know what the suppository for the polyp contains, so I can't tell you if it's safe or not. Progesterone can be used concurrently with the polyp meds, no need to wait till you've finished those. Suppositories are used vaginally, but the creams can be too. Take care Wray

Sep 05, 2012
Worried a lot abt miscarriage
by: K.A.sachdev

Hi wray,

I m about 7 weeks pregnant...I have severe backache which doesn't allow me to do any work.i m suggested to take gestofit 200 vaginally as get brown discharge.Bt inspite of having medicines n all I don't knw y my back aches very badly n I can't do anything.someone told me it can b twins thts y back ache is so much...n now I m worried tht even if it is twins I dnt want to loose
My babies...will gestofit help me to avoid miscarriage ? Wat is the reason for my severe back ache ? N Wat Extra care do I need to take ? I dnt want to loose my babies at any cost...

Sep 06, 2012
Worried a lot abt miscarriage
by: Wray

Hi KA It appears your oestrogen to progesterone ratio is too high, hence the brown discharge. Back ache can be one symptom of this too, in fact many women get this the few days prior to bleeding due to progesterone withdrawal. The gestofit will help prevent a miscarriage if there's a possibility of one due to low progesterone. I suggest you open a capsule and mix the contents with a small amount of skin cream, then rub that over the painful area on your back. I've found progesterone works better if applied directly to any painful area. It's absorbed as efficiently through the skin, as it is in the vagina. See our page on Delivery system for more info. Vitamin D is essential for the growing foetus and to prevent miscarriages, so please consider taking 5000-6000iu's per day, see here, here and here. An ultrasound will tell you if you have twins, your doctor can help you with this. Take care Wray

Oct 08, 2012
TTC, but...
by: ani

Hi Wray
I and my husband have been TTC for the past few months (Dec 2011). [For work related reasons we haven't been able to be together for few days during the fertile period in some months, so I can’t say that we had been actively trying for the past 9 months]. The last two months, I felt I had most of the pregnancy symptoms- nausea, bloating, headache, increased body temperature, mood swings, etc. Although I understand these could be PMS symptoms, I usually have only mood swings before my periods and not any other symptoms. Given this, on having so many symptoms I was hopeful to be a pregnant, but eventually I ended up having my periods. In September, when I was very hopeful of being a pregnant, I had a period (on 9th Sep) which was only for two days (I usually have short periods – for3-4 days) and in October again when I had all the above mentioned symptoms and had a strong gut feeling that I was a pregnant had a period which started off with spotting on 5th October and had severe abdominal pain on 6th with very less discharge during the first half of the day and then had normal to heavy discharge. (if I have abdominal pain during my periods its usually with heavy discharge, but this time, it’s not the case). Just wondering could this be a early miscarriage?
I am currently not in my home town and not comfortable seeing a doc. here. I would be back in my home town in 3-4 months. I wanted to get some help in the mean time and as I was browsing the net came across your site and so I am writing to you.


Other details

My age: 30, My husband's: 31
My weight: 45
I usually have my periods regularly for 28-30 days

Thanks and Regards
Ani

Oct 08, 2012
TTC, but...
by: Wray

Hi Ani It sounds as if you are having a very early miscarriage each time. Although I'm sure a doctor would dismiss this! I feel it's certainly worth trying progesterone to see if it will help. It's best if started before falling pregnant. We do have a page on Pregnancy you could look through, and another one here. One thing research has found out is that an early rise in progesterone is essential for implantation and to ensure the embryo is well attached, see here. It could be yours is not rising fast enough, by using progesterone this would assist the process. Please have a vitamin D test done, levels are low in most of us, and it's vital for ovulation, conception, the growth of the foetus and after birth during lactation. A low level reduces the benefits of progesterone, plus it causes miscarriages, see here, here and here. At the end of the pregnancy page are two videos worth watching. A major study was done on vitamin D and pregnant women. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although recent research indicates it should be 10,000iu's per day, see here. Another nutrient you could consider is taurine, it's also vital for the foetus, see here, here, here, here and here. Take care Wray

Mar 19, 2013
Can Gestofit delay periods
by: ani

Hi

We have been TTC for the past one year and I was on Siphene 100 for 3 cycles now (Jan, Feb, March) This month I had my follicular study done and on 13th day the readings were right ovary (16.3mm, 15.3mm) and left ovary (19.7mm) endometrium thickness 6 mm; I was advised to take HUCOG 5000 injection on 13th day and start taking Gestofit 400 SR; On the 15th day when I went for the follicular study, the tech said that 2 follicles are ruptured and asked me to continue Gestofit 400 SR till I see my periods. today is the 26th day of the cycle (usually have a 27-28 day cycle); I dont see any PMS symptoms till now; but my tummy is bloated for the past one week or so (not a usual PMS symptom for me). when can I take a HPT to get a more reliable result (as I read somewhere taking a HPT too soon can give a false positive result when HUCOG is taken) can progesterone delay my periods?


Aug 07, 2013
9 weeks gestofit 200
by: Anonymous

Hi, my wife is 9 month pregnent and our doc has adviced us to take gestofit 200 mg

Please advice if its safe to take.

Aug 08, 2013
9 weeks gestofit 200
by: Wray

Hi there It is safe, but won't help much, as oral progesterone is the least effective Delivery system, "The liver and gut region removed a mean of 96 per cent of the progesterone entering these tissues", see here. I suggest removing the contents of the capsule and emptying them into some skin cream, then apply that to the skin. We have more info on our Pregnancy page and another page here. Take care Wray

Nov 15, 2013
Susten 200
by: Deepika

Hello, I'm 28 and married since 6 years. I've been taking Contraceptives Diane-35 for 5 months this year from april to august as I've hormonal imbalance and breakouts of severe acne on face. We started planning since september and now I'm 5 weeks pregnant for the first time. No history of miscarriages. My doctor has prescribed me susten 200 for vaginal use, she said everything is normal. I've used 4 of those, been reading online about it and very confused as I read that women who have a history of miscarriages should take susten 200 and also the side effects are weight gain, hair loss, hirsutism, fever, fluid retention, acne, allergic skin rash,etc. I'm in a dilemma that why would my doctor prescribe me susten 200. Please advise. Thank you in advance.

Dec 06, 2013
Gestofit 100mg tab
by: Anonymous

Dear Wray,
Read your comment, I am now 3 months pregnant and initial days of Pregnancy I had slight bleeding for around 20days and after that it stopped. My doc suggested to take Gesto fit 100mg ?? For how long will this Tab be contined. As this Tab has lot of side effects... I am worried.

Please guide.

Jan 26, 2014
use of sustain sr 300mg tablet
by: nitu singh

hi Wray,
My question is it safe to take 300 mg sustain sr 300 mg tablet at 7th month of pregnancy,is there any side effect on mother and baby

Feb 10, 2014
about gestofit
by: Anonymous

hi i am 18months pregnent n i am taking orally 600mg/per day orally gestofit as suggested by dr. but i want to know if it will effect to my baby health i was so worry about this is my first baby,so do u have any suggestion

Jun 14, 2014
5week gestofit400
by: madhu

hi.

i had misscarriage 8 months ago. I got bfp only after 50 days last time. Advised to insert sustain 300vaginallybut i undergone dnc at 10 week due to blighted ovum.mine
is 35 days regular cycle. 40th day today. Feeling lik am pregnent bcoz of tiredness mucus plug nd more leukohrea. But stil hpt is negetive.my dr gave me gesto fit sr 400 tablets(not capsule) to take daily for 10 days at night. Is it usefull? Am i pregnent? If am not pregnt then gestofit will alow my periods to start or what? Am i having low hcg? Low progestron?plz help i dont wanna misscarry this time...

Jul 07, 2014
pregnancy details
by: Anonymous

Hai,
As I'm having pcod ,, doctors advised me to have hcg injection before the ovulation took place and have intercourse after 36hours... And after 36hrs they advice me to use gestofit 300mg 2/day... Does this help me to conceive

Aug 17, 2014
prostagen sr300 tablet
by: asha

prostagen sr300 tablet for what problem we should take during pregnancy and timing to take tablet

Aug 19, 2014
medicines prescription
by: Anonymous

Hi everyone,
I am in early pregnancy and doctor prescribed me 3 tablets today:-
1. Folizorb
2. Dubagest-200(progestrone)
3. Duphaston
Can any one tell me what are their significance in pregnancy. Should I start these immediately. Which medicine in above contain folic acid. Plz help as I know about progesterone but not about Folizorb and Duphaston. Which medicine in above will help the new one.

Waiting 4 reply!!!!!

Sep 05, 2014
5 week pregnent
by: Shashi sharma

I m 5 week pregnant and I have light brown and red spotting and ultrasound report is thick decidual reaction is seen and docter give dubagest- 200 is good for my baby developing . pls tell me

Sep 30, 2014
till delivery
by: Anonymous

Hiii , is it advisable to take susten 100mg till ma due date?now 7th mnth running...nd ma doctor advised not to stop dat tab;I had an bleeding issue in 5th mnth...and am having bicornuate uterus...wat ma question is it be safe to take till due date ...?

Nov 20, 2014
Progesterone 200 mg after Ovulation
by: Anonymous

Hi,

My periods are regular and am ovulating on time.Have been taking progresterone 200 mg vaginal tablets thrice a day. Last 2 months went unpregnant. This month,have been put again on progesterone 200 mg thrice a day. My question is - Can i conceive using these tablets ? As i am 14dpo today and getting back ache since morning. Please please help. Thanks!

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