Progesterone, Hypertension, Fasting Blood Glucose

by Alfredo
(Colombia)

Hi Wray: I just wanted to let you know my success with health problems I always had but have changed a lot since on progesterone cream.

Hypertension and fasting blood glucose.

I had hypertension since I was checked in my teens (I am 62) and for the last 10 years my fasting glucose was above 115 ( I am not overweight and after meals glucose is below 100. I exercise everyday).

Now my systolic blood pressure has come down around 10 points. My fasting glucose was this morning 87!!!!for the first time in my life. Unbelieveable....I am very happy with those resaults.

I want to check with you some problems with my sleep since I started with progesterone. The reason I came to your site was looking for answers for my prostate hyperplasia. About a month ago, I initiated with 20 mg of progesterone in the morning and evening, but immediately I could not sleep. I stopped the cream and normal sleep pattern came back (I usually have sleep problems, I wake up and may take hours to go back to sleep).

I started the cream again, 20 mg in the morning, and my sleep is not altered that much but it takes me 30 minutes to an hour to fall to sleep. Have you seen this type of sleep problems? Any suggestions?

I would like to implement the twice a day progesterone because I feel it is improving my prostate situation but I am stuck with insomnia.

Best wishes,
Alfredo E.

Comments for Progesterone, Hypertension, Fasting Blood Glucose

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Oct 03, 2011
Progesterone, Hypertension, Fasting Blood Glucose
by: Wray

Hi Alfredo I'm so delighted the progesterone has helped you. It does help hypertension, as it blocks the aldosterone receptors. Aldosterone causes water retention, which can lead to high BP. Progesterone is also a potent vasodilator, another reason it could have gone down. Progesterone can help blood glucose too, see here and here. It could be your oestrogen level is too high, this doesn't surprise me, as none of us can avoid it. There are over 100 oestrogen mimics in the environment now, see the website Our Stolen Future. Oestrogen upsets blood glucose, it's an inflammatory hormone, and the reaction you had to the progesterone suggests you have Oestrogen Dominance symptoms. Men do get this if levels are too high. Interestingly progesterone stimulates adenosine, as seen in the paper above. Adenosine is involved in the sleep/wake cycle, see here, here, here. The neurotransmitter dopamine is also involved in the sleep/wake cycle. I've found that the precursor to dopamine, the amino acid tyrosine, can calm a mind too active at night. It might be worth trying it, but please see our page on Natural Antidepressants which explains how and when to take it. It is best to use progesterone a minimum of twice a day, as levels drop after about 13 hrs. It's safe to go far higher than the 20mg/day you are currently using. Over 1200mg/day are given via IV transfusion to TBI victims, mostly men too, see here, here and here. I've run out of space so will start a new comment below. Take care Wray

Oct 03, 2011
Progesterone, Hypertension, Fasting Blood Glucose
by: Wray

Hi Alfredo You might like to read these comments from other men, see here, here and here. Finally please have a vitamin D test done. A lack of this vital nutrient causes BP to increase. It's a potent anti-inflammatory, which will help the BHP. In fact it can prevent prostate cancer. A lack also causes insomnia too. For more info on testing etc, see the Vitamin D Council, GrassrootsHealth Birmingham Hospital and Vitamin D Links websites. This is an excellent video to watch too, see here. Plus this chart on Disease Incidence. Take care Wray










Oct 06, 2011
Estradiol, Higher Dosage And Vitamin D3
by: Anonymous

Hi Wray, I had my estradiol checked several times and it always comes back below 30, which I believe is within normal range.

I am trying to slowly introduce a second progesterone doses at night starting with less than half of what I take in the morning. So far, I am doing OK.

I have stopped taking vitamin D3, 5000 mg per day, since I read conflicting information about the safety of this supplementation because it is synthetic. I usually exercise out in the sun for 30 minutes a day with arms and legs exposed so I think my vitamin D is not very low.

I will keep you informed of my progress. Thanks Lot for your caring answers,

Best wishes,
Alfredo E.

Dec 14, 2011
Estradiol, Higher Dosage And Vitamin D3
by: Wray

Hi Alfredo I can't believe I missed this reply of yours! I'm so sorry, I've no idea why, as all queries should come through to me. The range for oestrogen in men is 10 - 50 pg/ml, so <30 does fall within range. I really need to do more work on men's hormones, I have no idea what the ratio of oestrogen to testosterone or progesterone should be. I've found in women it's the ratio of progesterone to oestrogen which is critical, not so much the level. If oestrogen is very much higher then all hell breaks loose in them. Vitamin D3 is made by irradiating lanolin, taken from the wool of sheep. It's exactly the same process as the way our skin makes D3, the sun irradiates the cholesterol in and on our skin. Vitamin D2 (ergocalciferol) can be synthetic, as it's only made naturally in fungi. In fact a study has just been published showing D3 to be far better than D2 for humans, see here and here. The second paper shows supplementing with D2 reduces the levels of D3. Although you say you have been taking D3, I would be surprised if it was synthetic. Dr Mercola warns about D2, see here. See here too. Colombia lies across the equator, so you should be getting plenty of sun, at the right angle too. If living far north, ie in northern Europe or Canada, the angle becomes too oblique from autumn to spring to make any. But I still feel a vitamin D test should be done, as levels do fluctuate. Stress drops it very quickly, as it does progesterone. Take care Wray

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