Progesterone boosted my 'Quality of Life'

by Greg Naylor
(Victoria, Australia)

I have final stage prostate cancer with bone metastaces. I am now 'castrate resistant' to Zoladex hormone implant treatment and there are no further treatment options available except pain management.

I have been using natural progesterone cream for over a month and it has turned around my poor quality of life.

Before using progesterone, I awoke every morning in pain and distress requiring liquid morphine (ordine) and oxycodone tablets. These took a couple of hours to take effect.

My comfort zone was between noon and 5 pm when the pain and distress hit again and carried on into the night.

Since using progesterone, I rarely wake in pain or distress and have no real need for the breakthrough pain medication. I have also been able to reduce the strength of the fentanyl (opiate) from 100 - 75 mcg/hr patches.

My doctor is witness to the improvement in my quality of life as he has seen me continuosly over the two+ years of the disease.

If you know any cancer patient with a degraded quality of life, please show them this story or have them contact me by email.

Comments for
Progesterone boosted my 'Quality of Life'

Click here to add your own comments

Oct 13, 2010
 Progesterone boosted my 'Quality of Life'
by: Wray

Hi Greg Bless you for sharing this with us. We'll certainly let them know, particularly as we have many men asking about progesterone for BPH, rising PSA levels, cancer too. In fact many men are using it successfully for prostate and libido problems. I'm surprised you were given Zoladex, in view of recent research indicating testosterone is not implicated in prostate cancer. There is evidence that low testosterone might cause an increase risk in prostate cancer, see here and here. In fact there is little evidence that testosterone treatment causes either prostate cancer or it's progression, see here. And that oestrogen is a possible the culprit, see here, here and here. There's some evidence high prolactin increases the risk. Although in men with PCA the addition of testosterone does cause a rapid progression if they have been castrated, but not in hormonally intact men, see here and here. An analysis of 44 studies using testosterone treatment showed no evidence in an increased risk in PCA, see here. A 1941 study on one man initiated the androgen deprivation therapy for PCA, see here and here. There is also a possibility that epidermal growth factor receptors are involved, see here. Unfortunately there are few studies done on progesterone's effects in men, and none I can find on progesterone and cancer. Plenty for women, where it's been used successfully in a number of cases. These two papers are worth reading here and here. You'll notice one mentions blocking gonadotropin secretion, which ultimately Zoladex does. I'm not sure how much you are using, but please consider at least 100mg/day. It's safety level is very high, over 1200mg/day is given via IV transfusion to men who have suffered traumatic brain injury. Take care Wray
Nov 05, 2010
 Dosage
by: Greg Naylor

I am achieving this improved 'quality of life' using about 10mg progesterone a day - or two measuring spoons. What more could I expect by using a higher dose of 100 mg day?

I have a middle aged male friend with traumatic brain injuries that render him confined to a wheelchair and full time caring. He has been in this condition for about three years. Where can I find more about progesterone and traumatic brain injury?
Nov 08, 2010
 Dosage
by: Wray

Hi Greg I find higher amounts of progesterone more effective. For instance I would hope you could reduce the drugs further still, but have no idea if this would be the case with you. One thing I forgot to mention was vitamin D, please have a test done. A lack of this is implicated in many cancers, for more info please see the Vitamin D council website. And please see these papers too, here, here, here, here, here and here. This is an excellent paper with info on prostate cancer, by Prof. Hollick, see here. One study gave the serum level of vitamin D as low <50 nmol/l (20ng/ml), to high >80 nmol/l (32ng/ml). The authorities are now saying the min level should be 50ng/ml, up to 80-100ng/ml. I don't believe the progesterone will help your friend now, as it needs to be given within 24hrs after the injury. But please see these papers here, here, here and here. They've since found adding vitamin D to be of greater benefit, see here, here and here. Take care Wray
Dec 17, 2010
 Progesterone dosage
by: Greg Naylor

Hi Wray,

I had the mathematics wrong with the dosage I have been using. I am applying a 4% cream at the rate of 1 gram cream both morning and night. That equates to 80 - 100 mg progesterone a day.

A neighbor with metastised prostate cancer in the upper skeleton (shoulders) having seen the results I have achieved has also started using progesteron cream. He says that it has stopped the bone cancer pain but is ineffective on muscle pain.

Between us all, we will get the world to better understand the benefits of progesterone
Jan 02, 2011
 Progesterone dosage
by: Wray

Hi Greg I'm relieved the amount I suggested is the one you are using. I have women using up to 600mg/day for severe pain, there's no doubt it won't harm you or your friend if you increased the amount. 600mg/day is 30 times the 'normal' recommended 20mg/day women are told to use. Please look into the vitamin D I mentioned, this does help muscle pain. Progesterone normally does too. Vitamin D is so important, I can't stress it enough. Please have a test done, and ask your friend to have one too. And yes, with your support, and that of others, I do hope the word spreads. We are up against the establishment, and they don't like natural substances! Take care Wray
Jan 19, 2011
 Progesterone calculations.....
by: Anonymous

Wray, hi there. Just came to your page and have been reading alot.

I am a medical doctor working in family practice. I will be starting some progesterone and possibly testosterone creams. I am 49, libido is good but i am sure it can improve, have mild to moderate BPH, PSA is normal from last october.

I am planning to travel to philippines soon to meet my fiance and we may attempt to make a baby while i am there. Does progesterone decrease semen production ?

Is taking tesosterone and progesterone simultaneously redundant or unnecessary ?

Also could you explain how one calculates the amount of progesterone cream they are using based upon on the percentage of progesterone in the cream and how that compututes to mg/progesterone per day.

Thank you. Sanemind
Jan 21, 2011
 Progesterone calculations.....
by: Wray

Hi Sanemind I'm not convinced that men need extra testosterone, never mind the many women who are given it! We have many using progesterone to increase libido, reduce BPH, for stress, depression etc. There is evidence progesterone does increase libido and correct erectile dysfunction, if this should be causing them a problem too, see here, here, and here, here, here and here. I have found no papers indicating progesterone reduces semen or sperm counts. But oestrogen does, particularly the endocrine disruptors. It has an affect on the acrosome reaction, which could affect fertility, see here and here. And the sperm concentration, see here. If you use progesterone and testosterone concurrently, you will not find out which is helping. An either or approach would be better. There are so many creams on the market, most are 1.6% strength, some higher. I recommend 10-100mg/day for men, higher if need be. So a 1.6% cream would contain 16mg/ml progesterone, which works out at 10mg progesterone per 1/4tsp cream. Most creams are 60g or 2oz cream per container, so a 1.6% would say it contained 960mg progesterone. A 3% cream would have 1800mg progesterone in the container. Often the container doesn't say the strength, only the amount of progesterone. So you would divide the 960mg by 60g to find the mg/g or mg/ml. The specific gravity of a cream is slightly lower than water, round about 0.96, so I find it easier to think of them as the same. There's more info on our page How to use progesterone cream, scroll to the very bottom. Take care Wray

Click here to add your own comments

Join in and write your own page! It's easy to do. How?
Simply click here to return to Progesterone for men

Return to Home Page

Search over 3,000 pages on this site...

Do you have a progesterone deficiency?

This free questionnaire will tell you in 10 minutes

Just enter your email address and click the button...

Why do I ask for your email address? Simply so I can stay in touch. Your details will not be revealed to anyone


Do you have a question or concern?

See what's being discussed, ask for help, give your thoughts or experiences, or just browse...

See the FAQ pages...


Natural Progesterone Cream

Discover the facts...


Health care practitioners and therapists

Here's an
Associate Program
that may be a good fit for your practice


Your language

Translate this website into your language