progesterone and weight gain

by Debbie
(Canada)

I have wondered how many women out there have actually lost the weight of the hormonal imbalance after taking progesterone ..all I seem to do is gain weight all comments appreciated
thank you

Comments for progesterone and weight gain

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Feb 20, 2012
hormonal rush
by: muriel

you're right....read my page

Feb 20, 2012
Estrogen Dominance
by: CamperKat

Use the Google search bar on the left of this site, and type in "weight gain"...there are about 300 discussions of this, and you'll likely find info contained therein to be helpful.

And...any weight gain from using progesterone is because of estrogen dominance and it will eventually "go away"--type in "estrogen dominance", and you'll see what I mean.

Good luck to you.

Feb 21, 2012
Hi, Debbie
by: Mateja

Thank you, for asking this, Debbie. I am wondering about that, too. Before I begun with progesterone I was hoping that I will loose some weight but after 2,5 months on progesterone (250/mg) I gained another 15 pounds and still gaining.

Feb 21, 2012
Weight gain/Weight loss
by: Karenina

Hi Debbie,

The hormonal inbalance will have caused weight gain before you had started to use the Natpro Progesterone Cream. Once you use the N P cream you will gain weight initially due to Estrogen Dominance but when the progesterone kicks in you will begin to loose weight. I have seen it for myself. It will take time...Take care. Karenina

Feb 21, 2012
Weight loss??
by: Debbie

Thank you for you comments everyone any one else out there lost the weight and how long did it take

Feb 22, 2012
by Debbie
by: Wray

Hi Debbie You don't mention how much you're using. If it's the typical 20-40mg/day that will cause it. As both CamperKat and Karenina say it does go if enough is used, they both used very high amounts, Karenina still does. Put their names into the search field as CamperKat suggests, and you'll be able to follow their story, others too. Progesterone speeds metabolism, it can't cause weight gain. It's also an excellent diuretic, so prevents the water retention caused by oestrogen. There's more info about this on our TBI page. Please see our page on Oestrogen Dominance for more info on the weight gain. And for more info on How to use progesterone cream on this page. Take care Wray

Feb 22, 2012
Hi, Debbie
by: Wray

Hi Mateja I've corresponded with 3 other Mateja's from Slovenia, I'm not sure if it's the same one each time! Maybe you're the one with the asthma who also had weight gain? As I know I encouraged that one to increase to 250mg/day, but I've not heard back from her. Please have a vitamin D test done, and if low take 5000-10,000iu's per day. A low level reduces the benefits of progesterone. For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. You could also consider taking Calcium D-glucarate. Oestrogen is metabolised in the liver by glucuronic acid, the process is known as glucuronidation. Glucuronidation is one of the major detoxification pathways of the liver. It removes carcinogens, toxins, tumour promoters, the sex hormones ie, the androgens and oestrogens, mineralocorticoids and glucocorticoids, aromatic and heterocyclic amines, polycyclic aromatic hydrocarbons, various nitrosamines, drugs, fungi etc. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase reverses the glucuronidation process. It breaks the glucoronide bond between a toxin and glucuronic acid, and releases carcinogens, toxins and excess steroid hormones back into circulation. There's evidence beta-glucuronidase activity is increased in breast and prostate cancer. Calcium D-glucarate inhibits beta-glucuronidase, see here, here, here and here. Incidentally this enzyme is produced by undesirable gut bacteria, supplementing with probiotics suppresses the bacteria, and subsequently the beta-glucuronidase. And as CamperKat suggests please look around the site for other women with weight gain. Take care Wray

Mar 07, 2012
help what is happening
by: Debbie

All I do is get worse gained weight all over abdomne legs arms depressed +++ when will I see my body I am stopping this ...found out my estrogen is low low ...anything I can do to fast track what progesterone did
please anyone

Mar 09, 2012
help what is happening
by: Wray

Hi Debbie You still haven't told me how much progesterone you're using. If it's the usual 20-40mg/day then you will get gain weight. I gave you that page on TBI, the victims, mostly men, were given over 1200mg/day via IV transfusion. They did not get weight gain. When we're pregnant we can make over 400ng/ml per day, we don't put on extra weight. Only those women who's progesterone was low during pregnancy do. Some women use 1000mg/day, they don't put on weight. It's essential to use sufficient. Please let me know how much you're using. Take care Wray

Mar 10, 2012
Estrogen Dominance
by: Anonymous

Sorry for so many questions.
I read that if you use enough Natpro, you will avoid estrogen reaction. I am using 500 mg/day, but with that I didn't avoid problems. I would really like to know, what should I do? Should I use even more than 500 mg/day? For how long? Two months ago I started with Natpro because I wanted to feel better, but now I feel much worse and gained a lot of extra pounds.

About estrogen dominance: Does this mean that my body at this time is at greater risk of suffering from any serious disease (eg heart attack or cancer or anything like that?

About gaining weight: I read that if progesterone triggers estrogen, you gain weight, but only temporary. But I could not find anywhere, that someone actually lost that extra weight. As I understand term 'temporary', that means, it will disappear by itself. If I need some extra diet and more excercise, that doesn't mean, that gaining is temporary. It means, that it will probably stay forever.

I have never experienced so many problems when starting to use something for better health. But starting to use bioidentical progesterone cause so many problems that I am really very confused and sometimes I seriously doubt that I made the right decision.

Mar 11, 2012
Estrogen Dominance
by: Wray

Hi Debbie I don't mind how many questions you ask me, I'm here to help. And no, you are not at risk of getting any serious disease. The early days can be very difficult, even using high amounts as you are. I don't know what else is affecting you either. For instance do you eat or use any sugar, fructose or glucose or foods containing these sugars? Do you eat grains and legumes, as these both contain sugars, or the carbs they are made up of convert readily to glucose. Sugar in any form is the most damaging of all substances, as it leads to glycation. This causes oxidative stress, which in turn leads to Inflammation and advanced glycation endproducts (AGEs). We do have more info on our Nutrition page. I find the Paleo Diet the easiest to follow. Fructose, sucrose and glucose cause sex hormone binding globulin to decrease by 80, 50 and 40% respectively. This allows free testosterone and oestrogen to rise, which increases weight. In fact testosterone is notorious are causing visceral fat to increase, see here and here. Winter and dark gloomy days drop progesterone levels, large meals too. Excess phytoestrogens in food antagonise it. It's impossible to avoid the phytoestrogens, but the highest is found in grains and legumes. It could be your liver is not metabolising the oestrogen fast enough, or it enters circulation again. This can be avoided by taking calcium D-glucarate. Oestrogen is metabolised in the liver by glucuronic acid, the process is known as glucuronidation. Glucuronidation is one of the major detoxification pathways of the liver. It removes carcinogens, toxins, tumour promoters, the sex hormones ie, the androgens and oestrogens, mineralocorticoids and glucocorticoids, aromatic and heterocyclic amines, polycyclic aromatic hydrocarbons, various nitrosamines, drugs, fungi etc. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase reverses the glucuronidation process. It breaks the glucoronide bond between a toxin and glucuronic acid, and releases carcinogens, toxins and excess steroid hormones back into circulation. There's evidence beta-glucuronidase activity is increased in breast and prostate cancer. Continued below.

Mar 11, 2012
Estrogen Dominance Part 2
by: Wray

Hi Debbie Calcium D-glucarate inhibits beta-glucuronidase, see here, here, here and here. Incidentally this enzyme is produced by undesirable gut bacteria, supplementing with probiotics suppresses the bacteria, and subsequently the beta-glucuronidase. Silymarin from milk thistle also inhibits beta-glucuronidase, plus it helps the liver detox. Two women on this page, CamperKat and Karenina, both comment on weight lost after starting progesterone. You might like to also read these comments on weight loss reply to london and here. This is a very long page, put Jenine into control/find and you'll be able to follow the thread. And this one too on high amounts to feel well, see here. You might like to follow Annette on the website, she's been using progesterone for a year now, sometimes up to 1000mg/day or more. She also lives in Canada. This is one page here where she's made a comment. A woman called CL commented on this page too. She found it wasn't until she increased her vitamin D that her symptoms resolved. So please have a vitamin D test done. A lack of this nutrient reduces the benefits of progesterone. For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

Jun 03, 2013
weight gain
by: z0220e

I just began the progesterone cream today so I have not had any experience of weight gain as of yet. However, I live in fear of this happening. I am obsessive when it comes to weight gain and part of the reason I took a 28 day saliva test as well as a rather large amount of blood tested was to find out why I have gained 10lbs in the past year, as well as why I felt like I was losing my mind. I found out that my vitamin D was at a 20... So I am currently taking 10,000 IU of Vitamin D3. My saliva test showed that I am over the charts with progesterone when I am not supposed to be and when I am supposed to show it, it is almost non-existent. My estrogen levels are normal. I found out that I have luteal phase defect and this is why I have been having my period two times a month with each period lasting 12-14 days... This all began about 2.5 years ago. I turned 40 and within a year I had gained weight and my mood has been horrible. Depressed, angry, short temper, and at times even paranoia and extreme anxiety. I am a marathon runner and I go to bootcamps and various workout classes during the week. I watch what I eat, almost obsessively.. SO, I know myself. IF I keep reading that I am going to gain weight, I will not take the progesterone. I am sick of feeling the way I have been feeling though. I can say it was a relief to find out that I was not crazy after all, and that my hormones were in fact out of whack. My question to you is... does everyone who takes progesterone gain weight?

Jun 03, 2013
weight gain
by: z0220e

I just began the progesterone cream today so I have not had any experience of weight gain as of yet. However, I live in fear of this happening. I am obsessive when it comes to weight gain and part of the reason I took a 28 day saliva test as well as a rather large amount of blood tested was to find out why I have gained 10lbs in the past year, as well as why I felt like I was losing my mind. I found out that my vitamin D was at a 20... So I am currently taking 10,000 IU of Vitamin D3. My saliva test showed that I am over the charts with progesterone when I am not supposed to be and when I am supposed to show it, it is almost non-existent. My estrogen levels are normal. I found out that I have luteal phase defect and this is why I have been having my period two times a month with each period lasting 12-14 days... This all began about 2.5 years ago. I turned 40 and within a year I had gained weight and my mood has been horrible. Depressed, angry, short temper, and at times even paranoia and extreme anxiety. I am a marathon runner and I go to bootcamps and various workout classes during the week. I watch what I eat, almost obsessively.. SO, I know myself. IF I keep reading that I am going to gain weight, I will not take the progesterone. I am sick of feeling the way I have been feeling though. I can say it was a relief to find out that I was not crazy after all, and that my hormones were in fact out of whack. My question to you is... does everyone who takes progesterone gain weight?

Jun 05, 2013
weight gain
by: Wray

Hi z0220e Your symptoms are due to excess oestrogen, there's more info on our Oestrogen Dominance and Menstruation pages. From about age 35 we begin getting anovulatory cycles when we make no progesterone. This of course means oestrogen rises, and with nothing to counter it adverse symptoms occur. Anovulation increases in frequency through Peri-menopause until the ovaries stop producing viable eggs at Menopause. Oestrogen is a mitogenic, excitatory, inflammatory hormone. It stimulates cells, including fat cells, to proliferate, hence your weight gain. So yes, you will gain weight using too little progesterone, as it will stimulate oestrogen, it's essential to use enough. I normally recommend 100-200mg/day, but feel you will need at least 200mg/day. You might like to see these comments from high users, see here, here and here. We do have two more pages you could look through on Anxiety and Anger. Take care Wray

Nov 01, 2013
Actually lost weight
by: Anonymous

I started taking progesterone a week and a half ago. I've lost 5lbs. But I'm very active and I diet. I'm in the military so I do actually work out not just walk around the block. I had been 125 lbs most of my adult life, then all of a sudden gained 30lbs and lost my period. My doctor put my on progesterone and I feel awesome, I'm finally getting my symptoms under control and losing weight by the day!

Feb 11, 2014
Progesterone and weight gain.
by: Chelle

I have read many of your comments about too much estrogen causing weight gain.

I'm 47, have PCOS, I am also diabetic. I was having what is called peri-menopausal RAGE. I very up beat, friendly, laid back person until a 6 months ago and fits of rage started. So, my doctor put me on progesterone (oral) ... I love it... I'm calm and happy again... my old self. But this is month 4 on progesterone. Yep... I'm up 35 lbs. and still climbing.

How long do I have to wait to get more in balance with my estrogen and progesterone? Should I talk to my doctor about increasing my dose?

Any advise would be so appreciated.

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