Nightmare with pellets

by Sally M.
(Arkansas)

I am 58 years old. I had a hysterectomy at 48, due to fibroids and ademomysis, kept an ovary. I began having menopausal symptoms at about 52. Have a friend who had good results with bio-identical hormones, so I decided to give them a try this year. Do I EVER regret it! One month ago, I allowed the doc to talk me into subcutaneous estrogen and testosterone pellets. She also prescribed oral progesterone, DHEA, vitamin D and other supplements. (These did not arrive until a week after I got the pellets.)

I immedately gained 8 pounds, which is mostly in the breasts and belly. My breasts are extremely sore - feel like they are on fire. I am tired, my migraines (which I've had since I was a child) have increased.

Two weeks ago, the doctor added 20 mg of progesterone cream. When the symptoms got worse, she increased the dose to 40 mg. For one day, I felt like I was on a diuretic and thought relief was finally on the way. Wrong! All of the above symptoms increased with a vengeance, with nausea and dizzy spells added to the mix.

The doctor said the pellets cannot be removed. How long until they are out of my system? Might they cause permanent damage? Any suggestions what to do for relief?

I read your FAQs and the page on estrogen dominance. Very informative but scary!

Thanks.

Comments for Nightmare with pellets

Click here to add your own comments

Sep 03, 2011
Nightmare with pellets
by: Wray

Hi Sally I wish doctors were better informed about oestrogen and testosterone. Whether they are bio-identical or synthetic, they still have the same effect on us. It's a great pity they can't be removed, are you sure? It will probably leave a scar, but I think that's a small price to pay. Please see our page on HRT, and these papers here, here, here, here, here here, here, here, here and here on testosterone. It should never be given to a woman, it increases visceral fat, hence your weight gain, plus it increases the incidence of heart disease and cancer. Oestrogen too, plus it causes water retention and inflammation, hence your sore breasts. Progesterone is excellent for sore breasts, see here, here, here, here, here and here. I always suggest rubbing a progesterone cream directly on them. Oral progesterone is the least effective Delivery system as most gets destroyed by the gut and liver. And the amount you were taking is far too low, except to make things worse. I'm running out of space so will start a new comment below. Take care Wray

Sep 03, 2011
Nightmare with pellets
by: Wray

Hi Sally Progesterone is an excellent diuretic, so your feeling was correct. Amounts over 1200mg/day are given via IV transfusion to brain trauma victims, to prevent the oedema and inflammation that occurs, see here and here. DHEA should never be given to a woman either, as it increases the risk for cysts and cancer, plus increasing testosterone levels, see here, here, here and here. If you do consider increasing the amount of progesterone, please chose a system where it's absorbed well, and do read the page on Oestrogen Dominance again. It can occur when increasing the amount. Progesterone is excellent for migraines, it appears you have always had excess oestrogen, the Fibroids and adenomyosis indicate this, and low progesterone, see here, here, here, here, here and here. The only supplement I can agree about is the vitamin D. The minimum dose should be 5000iu's per day, and the blood level between 70-100ng/ml. Please have a test done, for more info see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital websites. Take care Wray

Sep 05, 2011
oral delivery method
by: Anonymous

Hi Wray -- can you please explain the difference between oral administration of progesterone vs. other medications? Why does the progesterone get destroyed in the gut when other meds you take orally do not? Trying to understand!

Sep 05, 2011
removing pellets, new side-effects
by: Anonymous

Thank you, Wray. I will talk to the doctor tomorrow and press her more about removing the pellet. They're very tiny, implanted in my hip (apparently disappears after you put it there), so she said she is not sure she could find it and that I may have to go through a lot of pain for nothing. I agree that a scar would be a small price to pay if it could be done.

I have never been sorrier about any decision I've ever made in my life. This weekend, my hair began thinning noticeably and that my rosacea (which has been under control for years) flared up. I am afraid to imagine what might happen next. I did increase my progesterone cream to 120 mg on my own. Now my breasts are even bigger and my tummy even puffier. (I may or may not tell her I did this...) I did remember that your site warned that things get better before they get worse.

If you know anyone else who has "survived" pellets, or of there's anyone out there who knows a story, please share. It seems that ever day is a new nasty "surprise" and I'd love to know what I could expect. Surely this cannot last forever.

Sally

Sep 06, 2011
oral delivery method
by: Wray

Hi there Progesterone is a steroid hormone, these are not manufactured in the gut, but within the body. There's no way of protecting them from destruction, apart from altering the molecule. Hence the advent of progestins or the synthetic forms of progesterone, or the synthetic oestrogens. Most of the destruction occurs in the gut, with the acidity of the stomach and high alkaline pH of the intestines. What little progesterone gets through to the liver is metabolised to allopregnanolone, this is an excellent analgesic. But if progesterone is used via injections, suppositories or creams, far more gets carried to the liver, so the analgesic effect is greater. Take care Wray

Sep 06, 2011
removing pellets, new side-effects
by: Wray

Hi Sally Strange they disappear, as they are designed to release the hormones on a continual basis. If it can't be done, I can only suggest increasing the progesterone substantially, to counter their negative affects. You'll have to experiment with the amount, some days you'll find you need more, others less. It all depends on your stress levels, as stress drops progesterone sharply. I feel you should try the 200mg/day, but you might need more. For encouragement see these comments on high amounts here, here, here and here. I suggest rubbing the cream on your face, see here. It's also an excellent anti-inflammatory. And don't forget to rub it on your breasts too. I'm so sorry this has happened to you, no one deserves it. Please see this page here on the pellets, it gives a list of the women who've written in about them. I do hope with sufficient progesterone you won't have a difficult time until they dissolve. Take care Wray

Sep 09, 2011
update
by: Sally M.

I spoke with the doctor earlier this week. She increased my progesterone cream prescription and told me to feel free to use it liberally. She also increased the oral progesterone. I'm using 60 mg in the morning and 60 mg in the evening of the cream. 300 mg oral at night. The nausea I had has improved, but my breasts are still swollen and on fire. I have eaten a little more than usual this week and I know I have gained some more weight. My clothes are even tighter. For the past month or so, my diet was extremely clean. I was afraid to take in too much or junk food for fear of gaining more. Looks like my fears were justified.

The doctor finally said a general surgeon could remove the pellet, but she couldn't do it herself. I know it would take a while to be schedule for surgery and I honestly can't afford the down time from work. I am hoping this will go away soon. She also said if I am miserable enough, she can put me on tamoxifen to block the estrogen. I don't know much about this except that it is given to cancer patients. I am not sure what to do.

Sep 09, 2011
P.S.
by: Sally M

The doc also ordered another saliva test, should have the results in a couple of weeks.

Sep 16, 2011
update and PS
by: Wray

Hi Sally I really believe you should be using only the cream, the oral is a waste of time and money. It's doing little to help you, and only putting a strain on the liver. Please increase the amount of cream you are using, I did suggest you try 200mg/day. You might need more, but this will be dependant on symptoms. The reason you've eaten more is oestrogen upsets blood glucose, plus of course it's causing water retention. This can occur immediately on using it, which causes an apparent weight gain, plus making clothes tighter. The testosterone in the pellet is not helping at all either. Whatever you do, don't touch tamoxifen, rather increase the progesterone, as that will suppress the excess oestrogen, see here and here and here and here. The saliva test will probably show you are full of hormones, and that you have sufficient progesterone too. But what most doctors/labs fail to look for is the ratio between progesterone and oestrogen, this is the critical factor. So both your levels could be high, or certainly in the 'normal' range, but the chances are the ratio will be skewed. When the results come back, divide the progesterone result by the oestrogen result, it should be 600:1 and over to feel well. We've realised this from Saliva Tests we run. You might like to read more about saliva tests here. And please have that vitamin D test done, and consider taking it too, it really does make a huge difference to how we feel. Take care Wray




Jan 21, 2013
I Wish This Was A nightmare on pellets
by: Anonymous

I had estrogen and totesterone pellets inserted about 6 weeks ago and my breast have been extremely swollen and painful since plus I am bloated, depressed and feel horrible. I am 56 and had a total hysterectomy 9 years ago. I was told that HRT would protect my bones and muscles, prevent breast cancer, helpme loose weight and give me tons of energy. My Dr. said I am just outof ballance and prescribed an oral progestin (which I am afraid to take. I could deal with all this but I had a routine mamogram a week ago and got the results yesterday. It is abnormal and I am so afraid. Everything you hear about pellets is wonderful. Completely safe. I would never have jepordized my health otherwise. I do not want this to happen to anyone else and I hope the lady who wrote before is ok. I am going to call my Dr. and ask for the cream and tell her about my report. Any advice is welcome, please.

Jan 27, 2013
I Wish This Was A nightmare on pellets
by: Wray

Hi there I find it hard to believe you were told HRT would "protect my bones and muscles, prevent breast cancer, help me loose weight and give me tons of energy". If you read through this page I've given, you'll see it does none of those things, can increase the cancer risk, and will most certainly cause an increase in weight. Oestrogen is a mitogen, causing cells to proliferate, including fat cells. It also causes water retention too, see here, here, here and here. Testosterone is notorious at increasing visceral fat, see here and here. Plus it increases the risk of cancer, insulin resistance and heart disease, see here, here, here, here here, here, here, here and here. Please avoid the progestin, it will only compound the problem. Have a look at our page on Contraceptives for more info about them. I suggest you start using very high amounts of progesterone, at least 200-400mg/day to counter the affects of the hormones you've been given. We have more info on our page How to use progesterone cream and the Menopause page. Take care Wray

May 14, 2013
Pellet Nightmare!!!!
by: Sheila

As a nurse,I conisdered myself to be informed!After going thru a hyst,2009,I began pellet therapy 3-motns later.I had been on Climara Patch since I was 32 years old due to early ovarian failure.SO,obviously,thinking I would definitely need supplementation after hyst.I went for the therapy.BIG MISTAKE!After two pellet sesssions,two months apart,they call me one day after going back for bloodwork and ask me can I come in asap.I say,sure I;m in town,so they tell me to come on by".When I go in the nurse comes in,never saw the doctor in person",she states"we think you are pregnant".For a minute"I thought I was having a bad dream.Then I get myself together,and I say"Are you crazy,you better look at my chart again,hyst. remember"?You people are crazy."Nver went back.I gained twenty punds,I had lipo,breast reduction.If I can give any advice-NO PELLETS!Go with the progesterone cream and estrogen patches for supplementaion.If you need testosterone,cream or shots!This is the only way for women to avoid the side effects!I'm on patches again with testosterone shots twice a month.Progestrone cream I buy at the health food store-just as good as prescription.Stay away from these clincs that promote hormone therapy.Find a good practioner and go from there.May Hells wrath come down on the docs that are pushing hormone mills for that greedy dollar.May their assses have to carry the load we do!

May 18, 2013
Pellet Nightmare!!!!
by: Wray

Hi Sheila Thanks for your comments, which I feel all women should read. Some women seem able to cope with them, but I'm not in favour of extra oestrogen, see our page on HRT. And testosterone should never be given to a woman, it increases the risk of cancer and heart disease, see here, here, here, here here, here, here, here and here. It also causes visceral fat to increase, in fact testosterone is certain to give a middle aged woman a middle aged spread, see here and here. Take care Wray

Oct 20, 2013
bioTE Pellets - miserable
by: Anonymous

I had a total hysterectomy at age 42 and was taking cenestin (estrogen) and felt ok. I then decided to do the estrogen/testosterone pellets 3 months ago. I immediately gained 8 lbs. in two weeks, I started to have swelling in my fingers and toes which now has become unbearable. It hurts to walk or bend my fingers upon wakening. My libido increased but when you feel this miserable, who cares. They also discovered through blood work that I had Hashimoto's disease (hypothyroid). I have been on medication for that for 3 weeks. The doctor tried to tell me that the swelling was due to that but I highly disagree. My skin and hair became incredibly oily. My back is broken out and some on my face. When they took my blood work again at 8 weeks, I was at 40 for estrogen and 168 for testosterone. That is way too high. I'm ready for this to be out of my system and go back to taking the cenestin. It really makes me want to change gynecologist if they are this off on this stuff. I attended a seminar before doing it and they claim that no one has ever discontinued the pellets after starting them. I just want to know if all that I am experiencing is from the pellets, the thyroid or something else.

Oct 21, 2013
bioTE Pellets - miserable
by: Wray

Hi there It's the testosterone causing the breakouts and oily skin and hair. This is the reason teenage boys get Acne far more frequently than girls. Your level was way above the normal range, see our page on Hormone Testing. The swelling is due to excess oestrogen, it causes water retention. I don't feel any woman needs extra oestrogen or testosterone. The oestrogen you were taking comes with the same risks as any HRT, see here. Your doctor is wrong, the symptoms are due to the pellets, these are some more comments here. I doubt if anyone at the seminar would say women had discontinued them, they'd make no sales. If your Libido was low, you might like to look through this page. It seems dopamine is the most important thing for a good libido, progesterone too. This comment came in today, although by a man, it does give you some idea, see here. Lack of vitamin D can cause Hashi's, see here, here, here, here, here and here. A lack of iodine too, did they check your levels before giving meds? Probably not as they never do. Tyrosine and selenium are vital to the manufacture of T4 and T3, I doubt they checked these either. It's far easier just to sell a drug. Take care Wray

May 11, 2014
BHRT pellet therapy
by: Anonymous

I'm 54 and had pellet therapy. After 6 days I suffered a severe migraine and had to be taken to emergency care. I continued to suffer from migraines and headaches over the next 6 months. I'd had an ablation 6 yrs prior with no complications and my annual checkups were always normal. BHRT doctor (different dr from my regular dr) did not give progesterone with estradiol/testosterone tx. I began to gain weight and didn't feel great. After 3 months I began to have sever pelvic pain on and off so I had an ultrasound done. It revealed I had a large fibroid tumor and an ovarian cyst. My new Dr. was very concerned and immediately put me on progesterone. He recommended I have a complete hysterectomy asap. I went home and did more research about risk associated with estrogen/testostrone treatment with no opposing progesterone. Estrogen should NEVER be given without progesterone regardless if pt has had hysto in my opinion. My testosterone level was 240 which is way too high for women and prolonged periods of high levels of testosterone can cause insulin resistance. I didn't have hair loss or acne but my glucose levels were high. After surgery the pathology report came back very alarming. Had I gotten a second round of pellets I would be fighting for my life from ovarian cancer! BHRT is a highly specialized field and should only be done by practitioners with 20 plus yrs experience. I wouldn't recommend pellet therapy because there is no way to adjust once they are in. It takes 4 to 6 months to completely dissolve. Additionally thyroid treatment seems to go along with BHRT but if you have Hashimoto disease iodine can complicate tx. Best advice I could give from my experience is do your research. There is a ton of info out there from different sources. However, there are a wide variety of opinions which can make it difficult for non-medical people. I suspect we will see serious complications surface and lawsuits from BHRT pellet therapy because more and more inexperienced practitioners are treating patients to capture the financial upside. Its been 8 weeks since surgery and I'm feeling better. I take very low dose of estrogen/progesterone/testosterone troche. Testosterone is produced from outer lining of ovary and I believe a low does is needed and safe. I researched this in depth and that is my take away. I hope my story will offer some addition info and a different prospective.

Aug 31, 2014
troche problems
by: Anonymous

on troche my dr raised my testosorone levels 5wks ago and started to get hair growth on chin pimples and my hair is falling out I am so scared . waiting blood results I am so scared my hair is not going to come back

Mar 15, 2015
low estrogen
by: Anonymous

Hi Wray My blood estrogen is 0.3. Testosterone is normal. Dr never asked for a progesterone test. Wants to put me on BioTe pellets. I don't want to but have miserable hot flashes, night sweats, fatigue, inflammation, heart arrhythmia, angina, bloated, indigestion problems, the list goes on and on. I had a complete hysterectomy 10 years ago and I'm worse off now than before. Please help.


Mar 26, 2015
Pellets are horrible!!
by: Anonymous

I wish I had found this website before I started the pellet therapy. I had a hysterectomy 10 years ago and cannot take synthetic hormones due to migraines. My initial lab work on 07/03/2014 was FSH 77.1 and Testosterone <17. On 07/17/2014 I had 125mg Testosterone and 12.5 mg of Estradiol implanted. Repeat lab work on 08/27/2014 revealed FSH 43.2, Testosterone 124, Estradiol 27.9. I was re-pelleted again on 11/19/2014 with 10mg Estradiol and 137.5 Testosterone. Repeat lab on 02/17/2015 revealed FSH 36.4, Testosterone at 122. Even with my Testosterone being that high, the dr added more pellets on 02/26/2015 - 6mg Estradiol and 137.5 Testosterone. I was already having trouble with acne on the 02/26/2015 visit and questioned him putting in more testosterone with it already being that high. Mind you, normal is 17-76! I went to a different provider last week with horrible symptoms...migraines, acne on face, chest and back; bleeding gums, depression, horrible taste in my mouth, crying, irritable, itching, no interest in doing anything, no self-worth, night sweats, etc. My "new" provider decided to do lab work. My Estradiol level is at 152 and Testosterone level is 467!!!! I am being told there is nothing that can be done about this and it will take about six months to get out of my system. I have even contacted Biote Medical and asked them what to do to make these symptoms go away and they said to give it a couple of weeks. Does anybody out there have any suggestions?

Apr 06, 2015
testosterone pellet nighmare also
by: Anonymous

Last year I started taking bio identical progesterone capsules prescribed by my Doctor and for the only reason of having increased irritability. They were compounded and I took them days 15-21, not sure if they were helping really I took the advice of my husbands friend who suggested seeing a Dr who specialized in pellet therapy. My husband is seeing him for his low testosterone and his weight gain.
I went to him and my testosterone was 24, avg is 17-76 but he assured me I needed the pellets and I even asked about progesterone and he right away said I needed testosterone. WHAT A NIGHTMARE! After the pellets and about a week into it I was even MORE irritable! I'm gaining weight where I should be losing as I'm more active than ever! I have NEVER had acne or zits on my forehead NOW I am breaking out on my forehead and chest and back and finding black hairs on my chin that I NEVER had before!!!!!!
I had my injection the middle of Feb and now just waiting for it to GET OUT! Went to another doctor and going to try the creams. Just waiting for my saliva tests to come back on that.
I think the testosterone pellets is a money grab for sure when they try and give to women. So upset about all of this! ahghghghghgh

Apr 15, 2015
testosterone pellets
by: Anonymous

I too wish I found this site before I was injected with testosterone. I am a breast cancer survivor and have read about bioidentical hormones a great deal. I was so excited to find a local obgyn that dealt with bioidentical hormones. In my readings, I found that estrogens need to balance the progesterones to get the optimal health benefits especially for someone who was diagnosed with ER+Pr+ breast cancer. therefore, when this doctor only talked about testosterone pellets i immediately asked him about progesterone. He dismissed this and tried to downplay my readings stating that he is an expert in the field. I was injected with 25mg of testosterone in late February and I have gained a lot of weight in my abdomen and have broken out on my cheeks and chin and continue to lose hair. I told him I already have thinning hair but he dismissed me. I have not gotten any benefits as I still have severe hot flashes and irritability. He told me my libido would improve which hasn't happened either. My testosterone levels went from 25 to 68 and my estradoil is up to 213 which scares me a great deal. Do you have any suggestions for me and can I buy a progesterone cream on my own at a health store to counteract this estrogen? I really don't want to go back to this doctor.

Apr 16, 2015
testosterone pellets Part 1
by: Wray

Hi there I still find it hard to believe, after having advised women for nearly 20 years, that doctors still insist on pumping women full of testosterone! What on earth do they expect to happen, obviously exactly what's happened to you. There are studies they could read. The weight gain over the stomach that occurs in P-M and menopause, commonly called 'middle age spread', is related to hormones, particularly testosterone. But obviously if we're injected with it, the affect is quicker. In fact the menopausal ovary is an androgen producing organ, see here. Testosterone is notorious at causing visceral fat, see here and here. Plus the menopausal woman has a great capacity for producing oestrogen in adipose cells, see here. So the two hormones combined ensure a middle aged woman will get a middle age spread. Free testosterone rises if SHBG (sex hormone binding globulin) drops. Free testosterone is metabolically active, if bound to SHBG it's not. Fructose, sucrose and glucose cause an 80, 50 and 40% reduction in SHBG, see here. It's essential to avoid all sugars, even those hidden in grains, legumes and sweet, starchy fruit and veggies. Progesterone raises SHBG substantially, which causes testosterone to drop, see here. And this paper… "As testosterone progressively dominates the hormonal milieu during the menopausal transition, the prevalence of MetS increases, independent of aging and other important covariates. This may be a pathway by which cardiovascular disease increases during menopause.", see here. And more here, here, here and here. Continued below

Apr 16, 2015
testosterone pellets Part 2
by: Wray

Hi there It doesn't surprise me your oestrogen has risen either. The body has a fail safe method of reducing high levels of testosterone by converting it into oestrogen via the enzyme aromatase. Ironically this also occurs to men who are given testosterone replacement therapy. They start to develop Man Boobs due to the testosterone converting into oestrogen. And of course testosterone can and does cause Acne. And thinning hair! Excess testosterone also causes Anger and aggression. I could go on. We do make a progesterone cream you can order from our website. It's as natural as we can make it. If you do try it please read these pages on How to use Progesterone Cream, Oestrogen Dominance in particular, Peri-menopause and Menopause. We do have info on Cancer too. Take care Wray

Apr 16, 2015
help me balance hormones
by: Anonymous

Thank you so much for responding promptly! I really am interested in starting the cream. What dosage would you recommend given my estrogen level is 213? I also will look into a vitamin D home kit. I really can't wait for this testosterone to be out of my system. Is there a way to test my estrogen levels through a site so I know when my estrogen levels have decreased since I do not want to go back to this doctor. Also, do you think I should continue to take progesterone given my breast cancer history. Through my readings, it appears the balance between estrogen and progesterone is key. Thank you so much for any help you can give to me:)
I live in the Philadelphia/ baltimore area- do you know of any good specialists in this area?


Apr 17, 2015
help me balance hormones
by: Wray

Hi there The amount to use is impossible to tell, although I do say no less than 100mg/day, but in many instances 200mg/day is needed, sometimes more, particularly in the early stages. Please do have a vitamin D test done, it's so important. Not least a lack of it reduces the benefits of progesterone. There are a few labs who do testing without the need of a doctor, have a look at these ….
Direct Healthcare Access II Laboratory offer a comprehensive panel of tests, plus advice
ZRT Labs offer a comprehensive panel using saliva, blood or urine tests
Genova Diagnostics UK offer blood or saliva testing
Genova Diagnostics USA offer blood or saliva testing
Trace Elements offer mineral hair analysis
Analytical Research Labs offer hair analysis
Request A Test offer a full testing panel from A to Z

Please read the page I gave you on cancer. And these two here and here. I wish I could advise on a specialist, but I only know of one and he's in California. Take care Wray

Apr 18, 2015
thank you
by: Anonymous

Thank you for your information- I will read all this information and figure this out:)

May 11, 2015
Are BioTE Pellets Right for Me?
by: Anonymous

Wray,

I had a total hysterectomy in late 2013. My doctor put me on 0.05 mg Estradiol patch and eventually increased the dosage to 0.1 mg. This alleviated the hot flashes and night sweats for a couple of months, but the symptoms returned. Then I tried BHRT creams with estradiol, testosterone & progesterone, but it never totally helped with symptoms. In addition I was sleeping and had severe vaginal dryness and itching. After a lot of trial and error over a 7 month period I decided tried the BioTE pellet therapy. I was hoping it would be the answer to my prayers. The pellets last from 4-6 months. I am on my second round of them and my energy is non-existent, sleep is terrible and the brain fog is really scaring me. Not to mention the weight gain and lack of overall enthusiasm in life. I can tolerate a lot, but am at my wits end. What are your thoughts? Should I perhaps go back on the patch and supplement with
progesterone cream? Thanks for your time! :-)

May 14, 2015
Are BioTE Pellets Right for Me?
by: Joy

Hi there - another Anonymous asked about BioTE Pellets back in October 2013, not sure if that was you as your stories are the same.

Not only are pellets a disaster for you, they are disastrous for ALL who use them! No woman needs to take extra estrogen and testosterone as mentioned in the comments on this thread by Wray. Please read these comments, you will find the answers to your questions. Wray gives a page to read where people who have been on pellets have written in and advised against them.

Please read the this thread carefully.

May 17, 2015
ok Wray what TO do instead of what NOT to do
by: Suzanne

I've been reading through this thread , I see I'm not the only one who had gained a ton of weight on hrt , I see that Wray has reasons why weight gain and water retention occur, but what I don't see is a clear choice for those of us who felt awesome on hrt but miserable with the extra 15 pounds . Am I missing something here ?

Jul 16, 2015
BioTe nightmare
by: Anonymous

In reading through these comments, I am just saddened. I, too, got the pellets in April 2015. I am now 3 months into them and the effects have been life changing. I have put on so much weight that I've changed my entire diet. I have cut out gluten, sugar and caffeine just to attempt to slow down the weight gain, however, 6 weeks into the diet change, I am still gaining weight. I had a total hyster. in 2004 and have been unable to tolerate HRT due to endo. The dr that talked me into these pellets said that they are completely safe and won't cause any side effects. I have NEVER had acne, not even as a teen (I'm now 41). I have acne on my face and severe acne on my chest and back. I can't wake up in the mornings, regardless of how much sleep I get and have NO energy.....NONE..... I am so mad at myself for not doing proper research. I also suffer from severe adhesions (4 surgeries) and, unknown if it is related, but the pain is worse than ever now. If you are considering pellets, I would beg you to find another solution.

Jul 28, 2015
Sorry
by: Anonymous

So Sorry! I am nearing the end of the 6 months of the pellets and am starting to feel like myself again. Hang in there... the acne is lessening and my abdomen seems less bloated and upset. I am praying by the end of August, I am back to my old self again. Even though I know my old self isn't the optimal me, I will welcome it now as opposed to this testosterone pellet effect on me!!!

Jul 29, 2015
ok Wray what TO do instead of what NOT to do
by: Joy

Hi Suzanne

I think perhaps you are getting confused. HRT is not natural progesterone, HRT are synthetic drugs which cause adverse symptoms, weight gain being one of them. Those who gain weight on natural progesterone, do so because they have excess estrogen. To overcome this, high amount of progesterone is needed in the beginning. Also if one is deficient in Vitamin D3 it reduces the benefits of progesterone which then causes weight gain.

Jul 29, 2015
BioTe nightmare
by: Joy

Hi Anonymous

I am so sorry that you have having such a hard time on the pellets, this is exactly why we advise against it. Your acne is due to excess testosterone. No women needs to take extra estrogen or testosterone as Wray has already advise. We should all start to ask our doctors if they would take the drugs prescribed and we also need to insist on seeing the side effects.

To be given the pellets for Endometriosis is madness, now I have heard everything? Endo is caused by oxidative stress and unless the stress is dealt with, you will battle to get rid of it. May I suggest that you try natural progesterone cream, it has helped so many who suffer from it. Please read How to use Progesterone Cream and Estrogen Dominance.

Also do you know what your Vitamin D3 level is as a deficiency reduces the benefits of progesterone and is essential for endo.

Hope this helps.

Aug 06, 2015
Hysterectomy
by: KLG

I have considered getting pellets, but after reading these reviews I am concerned. I am 45, I had a total hysterectomy at the age of 26, my hormones have not been the same since. I did the patch immediately after surgery, then switched to premarin, I'm currently taking estradilol inj. 2 ml every 21 days. This helps with the hot flashes.
Buy I have no libido, I have gone from 125lbs, to 210, I have no energy. Ihave tried low dose testosterone inj., and that didn't help with anything. So what can I do to help remedy these issues?

Aug 09, 2015
Hysterectomy
by: Joy

Hi KLG

Gosh what a young age to have a hysterectomy, was it cancer related? The procedure would have put you straight into Menopause so I am not surprised that your hormones have not been the same since. Premarin is probably one of the worst HRT's around. No women needs to take extra estrogen or testosterone for that matter. There are over 100 estrogen mimics in our environment as it is, why take more? Please read Our Stolen Future. It maybe helping with your hot flushes now, but it will cause problems for you in the long run. All drug based HRT have a potential to cause harm. Why don't you consider using progesterone cream, it does the job and without any side effects. Because of the HRT etc, you are suffering from Estrogen Dominance.

The jury is still out as to whether testosterone helps with libido, but progesterone does. Amongst other adverse things, testosterone can cause cardiovascular disease, see here and here and is probably the reason for your weight gain, that and excess estrogen caused by HRT.

I suggest that you drop the HRT and testosterone and use progesterone cream instead. Please read How to use Progesterone Cream.

Do you know what your Vitamin D3 level is as a deficiency reduces the benefits of progesterone and is also linked to poor libido.

Hope this helps.

Sep 19, 2015
Stomach Issues with Biote??
by: Anonymous

So glad I found this site! I too have been gaining weight on Biote despite exercising six days a week and being very strict about what I eat!

Has anyone else experienced stomach issues after you have been on Biote? Almost everything I eat gives me gas despite taking numerous and expensive probiotics!

Thank you!!

Nov 21, 2015
HELP!
by: Anonymous

I am 56 started going through menopause at 51 tried bio identical creams/trouches for 3 years and the last 2 years I've had BioTe pellets - at first I did est/test with added prog at night - seemed my body hated this combo I am currently on testosterone pellet ONLY. I also take thyroid meds for hypothyroidism As of this January I will have gained a total of 15lbs ! I am only 5'3" I workout everyday and eat clean for the past 40 years I've even done body building competitions in the past
I've never had a hot flash and I don't suffer from dryness
On May of this year 2015 my estrogen level was 24
I AM LOSING IT I'm SOOOOO miserable
I can't lose one ounce no matter what I do
I am considering going off the pellet
PLEASE ADVISE

Jan 01, 2016
Pellet nightmare!
by: D

Hi, I am 51 and have been post-menopausal for 10 years. I still have all my original equipment🙂. The hot flashes and night sweats, crazy head, depression & fatigue never stopped. I tried prempro first, started bleeding and never stopped. (After 10 years of no bleeding) Then tried compounded vaginal estrogen & testosterone with 200 mg micronized progesterone. Still bleeding. Had uterine biopsy, with atypical cells found.

Then Gyn put me on BioTe pellets. 10mg estrogen & 150 Testosterone with 400mg micro progesterone. After 1 month my testosterone is 318ng/dl. I am extremely anxious and panicky all the time.

My hair is falling out, I had large painful pimples all over my vaginal area. Then the pimples moved to my face & neck. Now at 3 months the pimples have slowed but my hair is still falling out. I do have more energy & libido.

My Question: does anyone know if my hair will grow back? I'm so worried! There are so many negative side effects after menopause and now this. I'm about ready to give up😂 Doctors don't seem to care. My gyno said my testosterone peaked too high! She put too much in! I am also scheduled for another uterine biopsy because I have atypical cells.

I need help!!!!! Anyone have the same issues????
Thank you!



Jan 03, 2016
Pellet Nightmare!
by: Joy

Hi D

You only have to read this entire thread to realise the negatives of pellets. No woman needs to take extra estrogen and testosterone as explained. You might consider weaning off and trying a progesterone cream which is extremely effective without all the side effects.

Please make sure that your Vitamin D3 level is with range as a deficiency reduces the benefits of progesterone.

Jan 07, 2016
Love my pellets
by: Lezlee

I got my Biote pellets in march of 2014. I love them. I've had no problems. I had absolutely no testosterone before the pellets so now I have energy to do my job. I feel good also. I have several friends who did this and they are successful. One had diabetes, and after getting some testosterone on board her fasting blood sugar went down into the 90's and have never before been that low. I lost weight and gained muscle.

I don't know what has happened to you ladies, but us here in south Texas feel grateful for having these pellets available.

I also have been on compounding progesterone 200 mg per evening since 2007 and it's the best thing that had happened to me regarding sleep.

Jan 26, 2016
I'm on my second round of pellets.
by: Anonymous

I have been reading your nightmare stories and wonder if your doctors have been trained right in pellet therapy. I haven't had any of the symptoms you're talking about. I had a total hest.4 years ago and they put me on estrogen (which by the way is pregnant horse urine), got breast cancer 9 months later.I had my reconstruction surgery on my breasts and found out about bioTe pellets from my doctor. At first I wasn't sure about them but my body had been without anything for several years. I take DIM for my breast health and vitamin D3. My doctor is awesome. I just had my second round a little over a week ago and feel great! Blood work is important so you know where your levels are. I've had some pimples but they have gone away with a good skincare system. No weight gain. My hair has quit falling out. I wasn't a big fan in the beginning but I love them now. I feel like they've saved my life. I live in Utah and guess I'm fortunate to have a great Dr.

Jan 26, 2016
Nightmare with pellets
by: D

Hi Anonymous, I'm in North Texas. My hair is still falling out in handfuls! Was your hair falling out due to the pellets or your cancer? I'm glad to hear your doing good!
Thanks!!

Feb 08, 2016
Get a new doc
by: Anonymous

I tried for years to a doc to listen to me but they all said - "well you are on the low side (thyroid, hormones) but that is to be expected, you aren't getting younger." Then I had to get new health insurance & a new doc - turned out to be a blessing in disguise, she actually listened to me and we discussed the pellets...

I had the Biote pellet inserted 2 months & I feel like my old self again. Doc also put me on a low dose of progesterone and 30 mg Armour and advise me to take D3 (that I do sporadically).

Yes my breast felt a little swollen at first and I am a little bloated but I'll take that any day to the tired, foggy-headed, crying, push-over menopause had made me. Not only have I regained my spine but I reclaimed my sex-life.

I am an RN and did the research on testosterone - new studies have debunked the relationship between heart disease and testosterone.

If you are having adverse reactions to HRT - get a new doc.

Feb 22, 2016
How long until the pellet works?
by: Annette

I have had mine in for exactly 2 months and the only thing that has happened is I have gained 10 pounds. Libido is still the big ZERO and no energy or clear thinking etc..Nothing but 10 pounds of blubber and now a little more depression because I look like a cow. It was supposed to help me lose weight not gain it..Even my husband said he didn't notice any change in my behavior (yes I am always grouchy and edgy and easily upset) for the better and maybe its worse. Luckily he has been hanging in there for 4 years and not pressuring me on the sex. ugghhh
BTW my doc is a specialist in hormones and the clinic is based on helping men and women with these issues. So they are specialist and should know..I am pretty sure in meno stage as no periods for 6 months. I still have all of my parts. Is there something else I should be taking?
My tests showed extremely low Testo and high DHEA

Apr 05, 2016
Bad news pellets
by: Anonymous

So I received testosterone pellets on Jan 20th, blood pressure went up to 259/193, very sick, who knew the lidocaine also included epinepherine of which I am allergic! Next I get horrible anxiety and depression. Then I wake up out of a deep sleep in atrial fib and have an ER visit and cardiology visit. Apparently developed a reaction to red wine. Now my hair and face are greasy, and I have full on acne. I am 56 and praying to get this out of my system. I begged the doctor to remove the pellets, no way. 4 more months and I pray nothing else happens.

Apr 06, 2016
Almost done
by: Annette

I think I'm done with mine. My second blood test confirmed that my testosterone had skyrocketed and it was not what my body needed. I'm starting on armour thyroid and Zoloft to see if I can get through this without losing my marriage or job. Maybe they can figure out women's Viagra :-) :-) :-)
I shouldn't complain about my symptoms as yours are way more severe. They extreme anxiety is a killer but it will go away when the pellet is dissolved. Most of it anyway. Live and learn I guess

Apr 11, 2016
Desperate!
by: Anonymous

Can someone who is a breast cancer survivor and who has been on progesterone cream and D3 tell me how they are feeling? I was on testosterone pellets which was the opposite of what I needed. I believe in the progesterone treatment but don't want it to backfire like the testosterone did. I'm having hair loss, bloating, weight gain, heart palpitations, insomnia, acne and hot flashes. My period is sporadic as of the last 6 months. I am 49 and I got ER+ PR+ breast cancer at age 37. Any info can help- pro or con.

Apr 16, 2016
Sore site
by: Anonymous

Has anyone had issues with soreness or lump at insertion site? Had my pellets inserted 5 weeks ago and site is still sore and can fill a lump. Had course of antibiotics . Dr went in again to see if maybe it was pellets but couldn't find anything. Can't even sit down. Hope goes away soon? Any ideas??

May 30, 2016
Very concerned
by: Tonya

I've been on the bio-te testosterone pellets for at least a year. My libido increased, energy was so so and I noticed more facial hair. After the 2nd or 3rd session I notice weight gain. Water retention and Visceral fat. I inquired about this being caused by the pellets and was told that initially it could cause some water retention but that that would correct itself. Well IT DIDN'T. .I'm now the heaviest I've ever been and I seem to have constant water retention. I feel horrible and to make things worse I look like a cow and for the first time in years I don't want to go on the beach in a two piece. I thought it was my eating but I'm really a clean eater and I began cutting out my occasional alcohol, did a 14 day paleo cleanse and did not budge an ounce. This is not normal for me, I usually can loose weight. I just turned 50 and I have all my parts, no doubt I'm pre menopausal but I really feel like I have not done my body any favors with the pellets. I am due pellets tomorrow but to my Doctors surprise I will be turning them down and asking to go back on my progesterone cream as I have been on the oral. Please someone tell me that by quting the pellets that I will get back to normal. I need some encouragement, please..

May 31, 2016
Pellets
by: Joy

Hi all - I am wondering if you are all reading this ENTIRE thread! Please pay particular attention to what Wray is advising. We do not recommend pellets at all, the negative effects that they have are simply not worth it. Wray provides links and study papers, please read them.

Thanks.

May 31, 2016
Problems with Pellets
by: Anonymous

Hi Tonya,

I feel your pain! You described everything I had except the bloating. Slowly, I am starting to feel like I did before I had the pellets. It's been almost a year. You will feel better, eventually. I am still trying to lose the excess weight I gained but at 49 it is coming off very slowly.

Jun 01, 2016
There is hope
by: Anonymous

It takes all my effort to lose weight after taking testosterone pellets one time!!!! I just lost 10 lbs and am back to my old weight by doing the Atkins diet. I am lethargic but I am being very struck with it. It's is the only thing that budged my weight in 1 1/2 yrs. I will begin to add berries and squashes next week for energy so I can go back to spin class and weights next year. I feel your pain- it's just not fair! Hang in there!

Jun 02, 2016
Weight loss after pellet
by: Annette

I can say that the pellet is officially out of my system because now I am having extreme hot flashes that I never had before and my weight loss was only due to my husband leaving me and Im sure my hormonal bitchy life had a lot to do with that and no sex life. But we are working it out now that I can actually get my mental thoughts together. I would NEVER recommend the pellets even if they do work for some, they are not worth it and the benefits are ???? none found with me..

Jun 02, 2016
Reply to coment anonymous
by: Tonya

Was your pellets just testosterone or did it have estrogen too?

Jun 06, 2016
Weight loss after pellet
by: Annette

Mine was Testosterone only and within a month it was so for above what it should be that I don't think I should have had a pellet maybe something a little more easily to control as far as dosage.
That wouldn't give the estrogen because of my family history of breast cancer...

Jun 07, 2016
Reply
by: Tonya

Annette, thanks. I only had the testosterone pellets. I had them well over a year. I had water retention and viseral fat gain. It helped my libido the first several times I used it but for the last two I didn't note much in that area. I was told that mine never reached the optimal level. I went back to the progesterone cream instead of the oral. I get much better results with the cream. Anyway, I'm hopeful and feeling less bloated...yay

Jun 11, 2016
BioTe pellets & Permanent Hair Loss
by: D

Hi, it took the BioTe pellets 7 months to get out of my system. The 150mg. Testosterone caused 40% Hair loss on the top of my head. I am 51 and have been post menopausal for 10 years. No one cares! My Gyno or the makers of BioTe. I have contacted them several times. They said my hair would grow back....it didn't!!!!!!
I feel so bad for women that are not being told the side effects before getting the pellets. I also had a lot of other disturbing side effects because my testosterone 'peaked' at 318ng/DL.
I haven't taken any other hormones at all after the nightmare with the pellets.

Jun 13, 2016
Biote
by: Anonymous

Sorry that happened to you D. If I were you, I would contact an attorney.

Jun 24, 2016
Back pain
by: Anonymous

Anyone have any back pain after pellets? Had mine put in 2weeks ago and after week have soreness all over, burning sensation. Hurts to lie down or sit. Site healed no redness, just pain! Plus not feeling any results yet.

Jul 06, 2016
Pellets are making me sick
by: Anonymous

I am 58 and postmenopausal. I decided on the bio identical pellets in February 2015. I seemed to do really well until my most recent insertion on 5/30/16----5 miserable weeks ago. When I say I did well prior to May of this year, I mean no hot flashes, increased libido, more energy; however I just can't seem to lose any wait, and I have hair in places that I never had to worry about before; also an increase in acne on my chest. But, again, I did pretty well until one week post recent insertion - 6/6/2016. I have been sick ever since. Headaches, insomnia, depressed, very scary anxiety, breasts that are so sore and lump I can't stand to touch them, chest pain, muscle aches, nausea. I called the GYN and they drew labs, but have yet to get back to me with the results. I went to my PCP yesterday and he said he feels sure that I have an overload of testosterone in my body and he is not surprised by any of my symptoms. He said I don't need the pellets EVER again. It's been 5 weeks, and every time I think I'm getting better, I am hit with a horrible anxiety attack. I feel wired and can't be still. My PCP is also awaiting the results of my testosterone labs. Says we will decide what to do at that point. I would tell everyone I know, don't take the pellets. I'm told I may not feel better for 6 months. Horrible.

Jul 07, 2016
Nightmare! Don't do it!!!
by: Anonymous

Think about it. If the dosage is too high and/or you have a horrendous reaction, like I did, you can't discontinue them. In hindsight, why would any ethical doctor recommend a months-long course of treatment that can't be discontinued??? Think long and hard on that one. I'm scared to death. I did it on the recommendation of a friend. That is NOT research. I feel like such a fool. Check out BioTE's website. Specifically their appeal to "new providers". It's ALL about increased revenue for doctors. Slick, slick marketing. Dosages individualized for each patient? How on God's green earth would they know (even with labs) what is optimal, normal or even safe for YOU. Everybody's body chemistry is different. Fact is, they don't know. It's a crapshoot that they'll gladly take along with your money. If you have BAD reaction? "Well my goodness, we've never heard of anyone having a bad response!" What a predatory racket.

Jul 07, 2016
Pellets are making me sick
by: Susan

At $330 a pop and the fact that insurance won't cover it, it's all cash in their pockets. I was told yesterday, finally, that my testosterone level is 220; the range is 2 - 45!!!!! The nurse said, "honey, your test results are normal and the doc said just give it time, and you'll feel better!!" How the holy hell is 220 normal when the range is between 2 and 45? I printed my lab results off the patient portal and it even says "HIGH" beside those results!!! I am so mad. I was able to finally pull up results from a year ago and my levels were high then, so this crap has been building up in my body for at least a year. I feel so stupid. I should have done better research. I am furious and sick, My primary care doctor says it's going to take time, lots of physical activity, and close monitoring by him. What a mess.

Jul 09, 2016
Too much testosterone as well
by: Anonymous

They gave me too much testosterone as well. I gained a significant amount of weight that I still haven't been able to lose, ugh!

Jul 23, 2016
Testosterone reached just about 500!! Nightmare!!!!
by: Anonymous

Like many here, I had a total hysterectomy, and they took both ovaries, so my gyn put me on Premarin, i was only 33 and 42 now. One year to the month, I switched to the pellet as had started to develop Melasma from the Premarin (another horrible side affect from HRT). BioTe product was supposed to be better all around and when the clinic showed me my blood work, they said I was borderline hypothyroid and had me start naturthroid as well. Come to find out later I didn't need and ended up needing an endocrinologist to help me for 4 months get my system back in shape. They told me to take the amount I thought was good so self medicate basically guiding me to take more though based on symptoms. Now back to pellets. After first round they ended up doing second insertion booster. After all was said and done I ended up with a few different doctors running blood tests as my testosterone had reached almost 500!! I had cystic acne so bad, Melasma had become out of control as estrogen had also gone crazy, I had massive hair loss on top of head and still losing some. The worst is I now have permanent constant growth of heavy "light colored hair" on my face which grows heavy that I have to have removed about every 4 days professionally. That is expensive too. I cannot express how much of a nightmare this has been and I have barely left the house much of e last year, the best advise Is to ask your doctor about Spirolactone (sp?). It is supposed to counter androgens, caused by testosterone which can cause acne and hair growth. Good luck to all of you but please, please listen to these warnings. I'm now doing the patch but still fighting left over side effects like Melasma (much lighter now though) and few others but far less than the pellet. I would love to get off of all HRT but afraid of aging any faster without Estrogen replacement as have already Been through early menopause. Maybe i won't though? Any feed back on that one would be great or anyone that has had success talking to the company regarding these horrible side effects as I would like them to take serious and inform patients. Thank you.

Jul 26, 2016
lawsuit
by: Anonymous

I wonder, with all this information, if we could sue the pellet company. Get this, after one insertion of testosterone, I went back to my doctor for a follow up and then got a letter in the mail stating that my doctor was leaving the practice to pursue the insurance side of gynecology. He didn't even have the decency to tell me he was leaving before starting me, a breast cancer survivor who questioned him thoroughly, on these horrible pellets. I should have known better as a few of his assistants had thinning hair and were overweight and I thought to myself, Why aren't these women using the pellets! I wonder what he will benefit financially working for the insurance company. Im thinking he probably is working hand in hand with the pellet company. It's a scam!

Jul 31, 2016
Help: does the weight go away when pellets are out of system?
by: FatFromPellets

I was always 137-140 pounds. I took bioidentical testosterone shots every three weeks for three years and it helped my sex drive, muscle mass, and body composition. I didn't take a very high dose, however. I have taken oral compounded progesterone for three years at 150 mg per night. No problem.

I had pellets inserted (100 mg testosterone and 25 mg estradiol) after blood work revealed a normal level of estradiol and a relatively high level of free testosterone. My doctor said that optimally the levels of each hormone should be higher and suggested pellets. He wanted to insert 100 mg of estradiol and I insisted he only insert 25 mg. Thank goodness!

I have gained fifteen pounds since the first insertion 8 months ago. I had my labs done after my second insertion and it revealed EXTREMELY HIGH (I don't remember actual amounts) testosterone, estradiol and progesterone.

It is four months since the last insertion. I have done Atkins for three weeks with zero effect. Before the pellets, I would have lost ten pounds in that time on the Atkins diet!

I just want to know: WILL THIS WEIGHT GO AWAY WHEN THE PELLETS ARE GONE? ANYONE.....??????

Aug 16, 2016
Horrible Experience
by: Sheila

I had the pellets inserted two months ago and I have had a headache the entire time. Just like most everyone else has said the Dr and nurse seem to think I am making it up. I am hoping and praying that this nightmare will be over soon.

Sep 22, 2016
Estrogen pellet horrible
by: Jackie

51 yrs old. Early menopause since age 40. Got compunded testosterone pellet Feb 2016 no problems. In June was time to get another
Decided to go with biote and decided to get estrogen pellet as well. After about 3 weeks later my breast got so sore and like fill with rocks.. They hurt soooo bad. Was also taking 100mg progesterone pill at night.. I heard if i backed off the progesterone a bit that might help my breast pain.. Big mistake i didnt take it for about a week and started bleeding. Havent had period in 10 years now for 2 weeks have bedn bleeding
Increased my progesterone to 200mg nightly to stop the bleeding but after 7 days still has not. Miserable Missrable Miserable

Sep 22, 2016
BHRT and thyroid
by: Anonymous

I've had two rounds of pellets. My only real problem with the therapy has been repetitive episodes of cramping and bleeding, which I believe is due to oral progesterone not being effective (think I will switch to a cream). I'm still not sure what I think about BHRT overall, although I have to admit it has been great for libido. I will say, however, that the clinic has done a super job getting my thyroid meds on track. I had a thyroidectomy years back and found that most endos are extremely ignorant about thyroid treatment. For ladies who are gaining weight and losing hair, they should definitely have a full thyroid panel done. Sex hormones and thyroid hormones do affect each other and this should not be overlooked.

Oct 20, 2016
To Jackie
by: D

My case is similar to yours. Early menopause at 40. I had so much bleeding after BioTe pellet (overdose). I ended up having a d&c and a hysreroscopy because the bleeding never stopped and my uterine lining was too thick from the hormones! It has been a year since my first and last pellets. My hair never grew back. I lost about 40% on top. I contacted Gary Donovitz, the biote founder. Go on the website and go through the health care provider part to get the 'real' answers. Email him, he needs to know! I don't think anyone cares, it's all about the increase in revenue!
It took about a year before I felt ok. It takes a long time for the anxiety and all the other symptoms to go away. There are also some embarrassing symptoms that no one has mentioned.
I hope you can find a doctor that cares.
Good Luck😊

Oct 21, 2016
D's comment about additional side effects
by: Anonymous

I just wanted to note that the most recent post from D mentions other embarrassing side effects. Yes!! I agree and have wondered if others ended up with the same as well. Did it ever get better?

Oct 21, 2016
Pellets
by: Anonymous

If you don't mind, what other embarrassing issues have you had because of the pellets?

Oct 22, 2016
Other side effects
by: Anonymous

I hope others will chime in so I'm not feeling so lonely in my response and yet I will admit a few.
I was one of the unfortunate ones that ended up with and overdose of the testosterone in my first pellet and it skyrocketed to over 200/300. I'm about 5' and 100 lbs so that is especially crazy!! As you all know, as women, we are supposed to be anywhere from 2-4 to 40 on a high end. Anyhow, I went from a full head of hair, a clear complexion and no facial hair to an intense case of cystic acne, facial hair (that I had to remove w a razor daily) and propecia (hair loss on top and hair line). It was BEYOND upsetting; full on depression and could barely leave the house. Even had to move out of boyfriend house and move due to embarrassment.
I ended up having to take accutane, spirolactone and finasteride to combat all the above. Has now been a year and a half and still on all three but much improved. The hair is now super light and soft but still grows all over my face. I fear that will always be the case now and permanently screwed from this overdose of testosterone. Plus, doctors not sure if hair will grow back all he way on top. Little bit coming back but not really and not even close to what was prior. I have scars from the cystic acne and have spent a small fortune in products and peels at dermatologist to help with all issues. Plus, whenever I start to lower the dose of accutane, it seems to want to come back as skin changed after the testosterone. Living nightmare beyond imaginable..

Oct 23, 2016
RE: Other side effects
by: Anonymous

So sorry to hear you are going through so much! I hope you have talked to an attorney about this! As for me, the facial hair did stop. I do have hair loss but now I believe the cause, for me, is my messed up thyroid that I am working with a doctor to correct. Make sure your ferritin (Iron) levels are at least 60, anything lower can cause hair loss. Sending hugs and prayers your way!

Oct 23, 2016
Testosterone should not be given to women!
by: Anonymous

That is horrible!!! These doctors prescribing this have got to be held accountable! Thank God I only took one dose of 25grams and that is only because I question my Doctor profusively! I am a breast cancer survivor and he downgraded it from 75 to 25 - always question and trust your instincts! I had all the symptoms as you and I am slowly going back after a year and a 1/2. My hair still isn't back. My weight still up about 5 lbs. I pray you have a reversal of your symptoms, but if not then we should form a class action suit. It's just not right to mess with women's bodies like this!!!- especially cancer patients!!!!

Oct 24, 2016
Other side effects
by: Anonymous

These side effects happened to me too, I had read up on the pellets and the terrible side effects, but I allowed my doctor to push them ....... BIG mistake. Read what people are saying here, you will see how terrible they are. I can't understand how this rubbish is given by doctors! It took a long time for things to return to 'normal' after I decided to use progesterone, things are still not 100% normal, but I am working on it and following info given on here.

Good luck, I feel your pain.

Oct 25, 2016
Everyone else, thanks as well:-)
by: Anonymous

Im still trying to figure it out and no, I've never spoken to an attorney. Quite honestly I was hoping that by now, a class action was already in place. To make matters worse, and you all seriously won't believe this, they threw me into hypothyroidism. They had me taking their nature thyroid at the " not really doctor", commercial office I went to when had mine done, ugh. Only if I'd known. So from January 2016 until This June, I have been having everything monitored closely by an Endocrinologist at a major hospital here. She was so pissed off at this place for not managing dosing, etc. thankfully, through her help, my thyroid is now back to normal again as there wasn't anything wrong with it in the first place.
Thanks for all of the words of encouragement as I was concerned I'd reached my one year mark and wasn't back together completely. It was good to hear some of you mention possibly could be 1 1/2.

Nov 07, 2016
I'm not complaining
by: Life has choices

4 months ago I had BioTe pellets inserted. At 42 I had a hysterectomy and ovaries removed. Been dealing the symptoms of menopause for ever. I did bioidential hormone pills replace for two years after hysterectomy and stopped when feeling great. Now a decade later in the past two years my skin in the groin became so thin I would bleed just wiping myself or have a bowel movement would tear my anus. Horrible Itching and couldn't have sex because it ripped inside my vagina from sexual activity.
In the past months since BioTe I no longer bleed from regular bathroom activity, I sleep, I have more energy. Yes I'm gushy and gained weight. I actually have enough energy that I'm trying to run as exercise.
While not every option is the best option for everyone we have to pick our poison so to speak. I'm going to have my second insertion of BioTe this week. I'm concerned for the weight gain but willing to see what happens. I can't go back to thin skin that rips and tears. I appreciate the information on progesterone. I will see about adding that to my daily routine.

Nov 08, 2016
Ovarian cancer
by: Trying to Make a Difference

I received my first pellet in August 2015. I did not experience the hair loss or acne. However, I did have weight gain. I was what the doctor considered peri-menopausal at 51. He never did any kind of exam on me - just took my blood to see what my hormone count was. He said I definitely needed the pellet, but I had to go to his Day Spa, not his physician's office to have it inserted. There, he also sold me several supplements that he said I had to have - they were not cheap, let alone having to pay for the pellet. I never actually felt any difference in my libido or my other menopausal symptoms. The follow-up blood test showed my testosterone levels to be very high. My abdomen began to swell and I was so uncomfortable I called him and had to leave a message. He prescribed me a water retention pill. It did no good. I couldn't eat or sleep. I finally got him to see me - I looked 7 months pregnant! He still did no physical exam, just a pelvic ultrasound. The images were on a big screen tv that I could see. He showed me my ovaries - one of them had a large white spot on it. He said not to worry about it!! I ended up in the ER 2 weeks later - I had Stage 3c ovarian cancer. I probably had the cancer before the pellet, but I believe the hormones fed the cancer and caused it to grow quicker. Why is there no testing done before administering the pellet?? Who is the oversight for this treatment? Why is there no lawsuit in the works?? Clearly no one is paying attention to this. I am in remission, but the rate of return for this cancer is 90%. DON'T USE BIOTE!!

Nov 13, 2016
Bio te pellets
by: DGL

59 year ol female. Tubal only, no hysterectomy. Have had 4 rounds of pellet insertions and compounded progesterone capsule supplement daily. Face and hair oilier than when a teenager. Acne breakouts. Sore breasts and nipples and gained 25 pounds despite careful healthy eating. Facial chin hair and mustache at corners of mouth, dark hair on my belly and sides of my face and increase in belly size and weight gain of 25 pounds. Have not gone back and am now out of progesterone compound about 1.5 months. Woke up to spotting when haven't had a period in 7 years! How long will this go on? What options do I have or should I seek? Haven't seen regular ob-gyn in several years. PCP does Pap smear annually and I get a mammogram annually. After first two insertions noted improvement in energy and libido, but by 3rd it no longer helped at all. Was back to feeling depressed and fatigued. Now with weight gain A1C is at 6.9. Triglycerides always a little high, glucose on the rise. Suggestions???

Nov 14, 2016
Bio te pellets
by: Alyce

You only have to read the entire post to realize that pellets are so wrong and cause so many horrible things. Suggest you stop having them it's as simple as that.

Nov 15, 2016
Re: 59 yr old female
by: Anonymous

I'm so sorry to hear you've joined our house of horrors so to speak. Also, typing from device so excuse typos as hard to see, lol. I'm in no way a medical professional and not providing med advice, just one of the above with MANY symptoms including the facial hair, acne, thyroid/ pituitary screw ups from this crap. First, if I were you, I'd stop with the pellets forever.

After trying to work with different docs that weren't very helpful, I've decided to work closely with my primary doc and focus on fixing the issue these pellets created which is hyperandrogenism. I had oophorectomy in 2007 and require something as only 42. However, I'm now doing a low dose patch and although no uterus, have learned through research that need some progesterone to balance out the estrogen. My pellet "fake" doc company (as I call it), never gave me any at all which also compounds the problem as leads to estrogen dominance (symptoms like yours and mine as well).

Here is a link to read about hyperandrogenism as I think it may get you on the right path to start discussing treatment options with your doctor. I've decided to stick with my primary and just work through it together. Now I am treating root cause and not just symptoms. The key for me is balancing my estradiol PATCH level with a natural progesterone in order to help cure the hyperandrogenism. Hugs!!

emedicine.medscape.com/article/273153-overview

Nov 17, 2016
Re: 59 year old female
by: Joy

Some good advice Ananymous, thank you so much.

Nov 29, 2016
I had a great experience with Biote
by: CFinFlorida

I'm 48, still menstruating, have Hashimoto's and went through a rough spell with night sweats, extreme irritability, slight depression, confusion, hair loss and exhaustion about a year ago. After tests and investigations, the doctor found Hashimoto's and low testosterone.

I've been on the pellet for 8 months and I love it. It brought my libido back, I have much more stamina, my mood swings and PMS are much less severe and the only side effect I have is back acne, which I control through my dermatologist and a lot of patience.

Too bad some of you have had a bad experience with HRT through the pellet; it has saved my sanity, business and marriage. Best of luck!

Nov 30, 2016
Beware!
by: Anonymous

Administering anything new, without being able to adjust the dosage is foolhardy. Please think about this. Your Bio-TE practitioner should be warning you. But my experience is - they won't. Too much money at stake.

Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Progesterone faq.


Search over 7,500 pages on this site...