Mrs Karen Robertson
by Karen Robetson
(Fife, Scotland, UK)
My son was diagnosed with Chronic fatigue syndrome(CFS) at the tender age of just 9 years. Very long story short, following an admission to Great Ormond Street Hospital, London (GOSH) in June of last year, it was clear from tests he was low in Copper. He also has Hyperisulineamic Hypoglyceamia, unusually low blood sugar, high insulin.
Following a year of trying to raise body copper levels with supplements but unable to raise Copper levels, he eventually had a 65 copper uptake test done, it is apparent he is absorbing copper in the stomach BUT it isn't incorporating well into Ceruloplasmin. Ceruloplasmin and copper urine level being low also.
I've struggled to find anyone to help us further so I have researched as much as I possibly can only to discover Estrogen elevates and modulates body copper and ceruloplasmin!
We have just done a saliva testing for Estrogen and Progesterone and although we don't have the levels as yet it appears both Progesterone and Estrogen levels are very HIGH.Unusual for a man I've been told. Certain we do at last have answers following 19 years off CFS type symptoms, including suicidal depression.
I'm very anxious to know the levels/ratio so we can work out what is required here to balance these two hormones. I really am hoping you may be able to guide me with this. If both Estrogen and Progesterone are high what on earth do I do to balance them???? If the ratio is less than 600:1 (progesterone to Estrogen), then do we apply Prog cream at high doses (200-400mg a day) even if Prog is very high? OR do we administer Estrogen cream, or both? It's a bit of an unusual case this as a faulty gene/receptor is involved here and the mechanism isn't understood at GOSH. The fault may lie in the Estrogen Receptor ERalpha.
Can HIGH Progesterone cause a Functional Estrogen deficiency?? In which case how on earth do we balance them?
I really would be sooo grateful for any input with this as I cannot find anyone who can help us.
I look forward to hearing from you