low estrogen and testosterone

by Kari
(USA)

Hello,

I am a 33 year old hashimoto's patient who just started NDT treatment. I also have secondary adrenal insufficiency (I am am on cortisol replacement currently). I have been taking vitex and stinging nettle for several months now. I believe my hormones are playing into all this so I had them tested by saliva from ZRT labs. I have a 30+ cycle with very little PMS but I feel absolutely horrible (brain fog, tiredness, frequent urination, heart palpitations) from cycle days 1-16. Stinging nettle seems to alleviate these symptoms somewhat. I am breastfeeding a 2.5 year old 1-2 times per day. I am not sure if progesterone is appropriate for me and would like some advice based on my recent labs.

Cycle day 21:
Estradiol (Saliva) 0.7 L pg/mL 1.3-3.3 Premenopausal (Luteal)
Progesterone (Saliva) 205 pg/mL 75-270 Premenopausal (Luteal)
Ratio: Pg/E2 (Saliva) 293 Optimal: 100-500 when E2 1.3-3.3 pg/mL
Testosterone (Saliva) 12 L pg/mL 16-55 (Age Dependent)
DHEAS (Saliva) 1.1 L ng/mL 2-23 (Age Dependent)
Cortisol (Saliva) 4.6 ng/mL 3.7-9.5 (morning)

Comments for low estrogen and testosterone

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Feb 16, 2017
low estrogen and testosterone
by: Joy

Hi Kari

You are correct, your hormones are involved. Your adverse symptoms indicate estrogen dominance, you are most definitely a candidate for progesterone, we all are actually if we do not supplement. You are also about to enter Peri-Menopause, please read the page so that you know what you are up against. Your progesterone:estrogen (E2) ratio is 293:1 as advised by ZRT, it should be around 600:1.

Have your tyrosine and iodine levels been checked? If they are low, the thyroid gland will not be able to make the two hormones T3 and T4. Antibodies against TPO are found in diseases such as Hashimoto's. Please get them to check your glutathione levels, if this is low the immune system struggles. I would suggest you take the precursor's to glutathione, the amino acids N-acetyl cysteine, glutamine and glycine, all readily available in health shops. Take at least 2000mg/day of each. Plus the mineral selenium, preferably an amino acid chelate, 200mcg/day. Glutathione needs selenium and there is also evidence that selenium reduces levels of thyroid peroxidase antibodies.

What is your Vitamin D3 level? Not only does a deficiency reduce the benefits of progesterone, it also affects thyroid issues, hashimoto, hypothyroid which all indicate a vitamin D3 deficiency.

Please take the time to read these pages and references:

How to use Progesterone Cream
http://www.progesteronetherapy.com/how-to-use-progesterone-cream.html
Estrogen Dominance
http://www.progesteronetherapy.com/estrogen-dominance.html
Selenium Supplementation
https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.87.4.8421
Vitamin D3 and Thyroid
https://www.ncbi.nlm.nih.gov/pubmed/24320141
Peri-Menopause
http://www.progesteronetherapy.com/peri-menopause.html
Vitamin D3
http://www.progesterone-info.com/benefits-of-vitamin-d.html
Magnesim
http://www.progesterone-info.com/magnesium.html
Testosterone
https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2009-0740

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