Just Starting Cream

I am 28 years old and after much internet research, I think I have finally found the culprit to my problems! I was diagnosed in 2010 with Hashimoto’s, Angioedema, Vitiligo, and Psoriasis. I have managed to get most of it under control through diet (and no meds) but am still getting various symptoms throughout my cycle. I have suffered from night sweats for the past 10 years and high prolactin levels. I mentioned a possible hormone imbalance to my GYN, which she brushed off. So, that’s how I got here.

I started the cream last week on day 16 but seem to be experiencing an increase in other symptoms that I thought were Hashimoto and thyroid related – not necessarily hormone. Mainly joint pain, along with eye pain, insomnia, and a little bit of weight gain. My mood has improved, energy is a little bit better, and other symptoms aren’t as bad but I still feel…off. I haven’t had any major night sweats but I do have a little bit of breast tenderness. I initially started out with 20mg and then increased to 40mg. Perhaps I need more? I have been using LifeFlo.

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Feb 09, 2012
Estrogen Dominance
by: CamperKat

The increase in your endocrine issues are because of estrogen dominance--you are not using enough cream, and you are therefore getting the bad reaction of the progesterone stimulating more estrogen to be produced as the body tries to balance the new introduction of progesterone. The only way to handle this and to quickly get balance is to use more cream. Use at least 140mg and up to 250mg per day, or more as Wray has suggested (use the Google search bar on the upper left, and type in "dosage" or "use more cream", etc.

When you up the dosage, expect the estrogen dominance symptoms to increase/worsen for a while--about 2 weeks is how long it takes for a woman of your age--but they will quickly settle down and lessen over the course of the next several months...yes, months...we are taking endocrine system here, and hormones can take a very long time to balance out. Do know that things will get better, and in the meantime, cut out all sugar, grains, dairy, legumes (including soy) and artificial sweeteners...as you know, Hoshimoto's and other immune disorders like rheumatoid arthritis have now been linked with gluten and grains-in-general intolerance.

Hang in there, and Good luck to you!

Feb 10, 2012
Just Starting Cream
by: Wray

Hi there Prolactin is a hormone, so high levels mean you do have a hormone imbalance, how could your gyn say otherwise?! Prolactin can rise for several reasons. Oestrogen increases mitotic and secretory activity of several cells in the pituitary, but particularly the proliferation of prolactin cells. If progesterone is high enough it suppresses prolactin, which is why pregnant women don't produce milk. It's only after birth when progesterone levels drop, that prolactin rises. It's often regarded as the hormone of lactogenesis, ie causes milk to be produced, but does have inflammatory properties too, see here, here, here, here, here,
here, here here and here. A lack of protein, in particular the amino acid tyrosine, slows down the production of dopamine. Tyrosine is the precursor to dopamine, see here. Dopamine drops with stress, principally because tyrosine is also the precursor to the two stress hormones adrenaline and noradrenaline. Tyrosine is also the precursor to the two thyroid hormones T3 and T4. All this strongly points to a lack of tyrosine in your diet. Normal dopamine levels suppress prolactin, if dopamine drops due to a lack of tyrosine or stress, prolactin rises. It appears you have high oestrogen and low progesterone and dopamine. What you have been through is obviously stressful, so it doesn't surprise me prolactin is high. Unfortunately you are to my mind using far too little, 40mg/day doesn't raise progesterone to even the luteal phase levels, see here. I recommend 100-200mg/day to ensure that levels do rise high enough. I've also found that if symptoms are severe far higher amounts are needed to overcome the problem. Continued below.

Feb 10, 2012
Just Starting Cream Part 2
by: Wray

Hi there This is evidenced in Traumatic Brain Injury studies, where amounts in excess of 1200mg/day are used via IV transfusion. Most of the victims are men, who normally make less 1ng/ml. All the symptoms you describe are related to oestrogen rising. This is always the case if too little progesterone is used, as it stimulates it at low levels, suppresses it at high levels. We do have more info on our page How to use progesterone cream. But above all please have a vitamin D test done. All these problems, Hashimoto’s, Angioedema, Vitiligo, and Psoriasis point to a severe lack, see here for angioedema, here, here, here, here, here, here,
here,
here, here and here for psoriasis, here, here, here, here, here and here for vitiligo, and here, here and here for Hashi's. Continued below.

Feb 10, 2012
Just Starting Cream Part 3
by: Wray

Hi there For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

Feb 10, 2012
Estrogen Dominance
by: Wray

Hi CamperKat Good to see you back again!! And I know what you're thinking, I have to do more info pages! I have started one on prolactin, another on vitamin D, another on skin problems and another on……..none of them finished, one day I hope! Take care and hugs Wray

Feb 11, 2012
Can't wait for those pages!
by: Mrs. A

Hi Wray, I am eager to get my eyeballs on those pages that you are doing! I am especially interested in the prolactin and tyrosine information. I breastfed for 14 months but had to wean due to starting a treatment protocol that included herbs that I couldn't breastfeed on. I wonder if prolonged breastfeeding creates a high level of prolactin for a longer time and therefore was one of the reasons I got a serious inflammatory problem. I have had it all my life but it hit another level after breastfeeding.

To the lady who started this page, I just wanted to say that I hope you start to see great improvement very soon! It is great that you have started on the cream and I think you are doing one of the best things you can do for your health. Good luck!

Love Mrs. A

Feb 11, 2012
Thank you, thank you, thank you!
by: B!

Ladies:

I am the author of the original post and I cannot thank you enough for the guidance. I gave up on my physicians shortly after I was diagnosed because their solution was either avoidance or meds. I turned to books and wonderful sites like this for knowledge and help. It makes me happy to know that complete strangers are so willing and anxious to help! Thank you!

I did up my cream earlier this week and the joint pain is gone (what a relief!). I am still experiencing a few symptoms here and there, but all in all, much better.

I have been taking Vitamin D 5000iu two times daily, as well as some of my B vitamins.

Wray, do I need to purchase a tyrosine amino supplement? If so, I will stop by the health food store today.

100mg of cream is a lot! I keep trying to rotate the sites...one day my left arm, the next my right, etc. etc. I am finding that by the end of the day, the site is sticky. Will this affect its effectiveness? Is this a sign my cream is not top notch or is this totally normal? Also, I have been trying to put it on 5 times a day but its hard to do while at work. Can I do two major doses or is it best to keep my doses at 20mg per application for best absorption?

My other question is: my cycle is supposed to start on 2/14. Do I continue at 100 mg throughout my period or take a break? So far, I have seen that a break is suggested, but there are also some circumstances where it is recommended to continue. Thoughts?

Thanks again!

P.S.: Any ideas when my sex drive will start to make an appearance? It's been missing for the past 9 years and I really would like her back! : )

Feb 13, 2012
Can't wait for those pages!
by: Wray

Hi Mrs A It's interesting you say you developed inflammation while breast feeding. I'll have to make a note to look into that. I can see it as a possibility if prolactin became too high. Incidentally using progesterone while breastfeeding is fine. And of course it will help to control the level of prolactin, preventing it becoming too high. I took a break over this last weekend, so now of course I'm behind again with the queries! Which means the pages will fall behind again too. Love to you too! Take care Wray

Feb 13, 2012
Thank you, thank you, thank you!
by: Wray

Hi B I'm delighted you're taking 10,000iu's vitamin D daily. Please have a test about 3 months after your first dose. With the multiple symptoms you're suffering from, you might find it's still too low, in which case you need to take about 20,000iu's per day. So pleased the increased amount of progesterone has helped the joint pain too. Although the progesterone will help the prolactin, it would be helpful to take the tyrosine too. Please see this web page we have on Natural Antidepressants, as it explains how to take it. I don't believe it the 'rotating the cream' instructions! The skin comprises 95% kertotinocytes, these have ample progesterone receptors, see here. Even the hair follicles and sebaceous glands absorb it well, see here So it doesn't matter where it's put, or how often it's put on the same place. For instance it's excellent for the face, see here. The cream should not be sticky, it should go in within seconds after applying it. The amount of times to apply it also depends on symptoms, you have many, so it would be advisable to keep levels topped up. But if you find it too difficult, twice a day will certainly help. I often just rub some on while I'm sitting at the computer. Either my face, arms or legs, it takes 2 seconds! I do recommend using it daily for 2-3 months to get progesterone levels up and to ensure it becomes the dominant hormone. It does no harm, and prevents oestrogen rising again when stopping. It's easy enough to get the cycle back again, there's more info on our page How to use progesterone cream. And if you want your libido back, I suggest you use more progesterone! Take care Wray

Feb 13, 2012
Prolacting/Breastfeeding/Inflammation
by: Mrs. A

Hi Wray,

Thanks again for your reply. I wanted to add that I remember not only getting inflamed but I had the worst migraines ever whenever my breasts filled up to near engorgement. It felt like my teeth were all inflamed at the root too, it was really bad!

Don't worry if you don't have the time to reply earlier! I'm so grateful for all of the replies you have done for me and if you reply at all, it's a great honor for your time and information.

Lots of love...
Mrs. A
xXx

Feb 14, 2012
Prolacting/Breastfeeding/Inflammation
by: Wray

Hi Mrs A I don't mind answering your queries, you certainly keep me on my toes! I've not found anything directly related to prolactin and breast pain/migraines, but it does increase pain, see here, it's also involved in autoimmune diseases, see here. I know you said you had a collection of these! Here's another, see here. And does this paper help? Well now I've found one, see here. And so far only one on prolactin and mastalgia, see here. It doesn't appear to be high on the list for investigating breast pain! In fact the treatments given read like a hit and miss, take it or leave it indifference, or am I being harsh!? See here. Considering the fact so many have breast pain, which can be treated with progesterone or iodine if low, it amazes me. Take care Wray


Feb 16, 2012
Another Question...
by: B!

Hey there, Wray! Thank you again for the helpful information.

I started the tyrosine supplement on Tuesday. I was in for a surprise with the B3. I took too much the first dose and had a flush. I probably should have read up on that a little bit more before I took it. :) I purchased the lowest dose I could find and oopsie! So, I was a little red on Valentine's - no biggie.

There are two nagging symptoms I am having. The first and most annyoing is this pain behind my eyes. I have had it on and off but it is particularly bad today. Do you think that is dry eyes or a sign of something else? Also, I have really bad danduff. I wouldn't necessary say "dandruff" but it is a thick coating of white stuff on my scalp. When I stratch, I get it under my finger nails. It's really gross. I know people with psorasis have dandruff but all other skin issues have been improving since I upped the dose of the Vitamin D.

Anyway, you have been excellent with all of your advice and I really appreciate everything you do. Is there anything I can do to repay the favor? Since I found your website, I have been improving. I have joined a gym and started running. My energy is coming back! Yay to that!

Thanks again!
B!

Feb 16, 2012
More Questions...
by: B!

Hey there, Wray! I hope you are doing well. Thank you again for the wonderful advice.

I started the tyrosine supplement on Tuesday. I purchased the lowest dose B3 I could find - took it without reading the instructions and broke out in a flush. : ) I was in for an experience and was a little red on Valentine's Day but all in all - doing pretty good. I am only taking 250 of Tyrosine in the morning. Should I be taking more throughout the day?

I am having two nagging issues. The first and most annoying is this pain behind my eyes. I have always thought it was thyroid related but I have definately noticed it more during the last 2-3 weeks. Is it possible that my eyes are just dry or is this a sign of something else? The second issue is what appears to be dandruff. I know people with psorasis can have dandruff. All my other skin issues are getting much better since I increased the Vitamin D but I still have a thick coating of white stuff on my scalp. If I scratch it with my nails, I get a bunch of white stuff under my nails. So gross.

Anyway, any guidance you can provide will be much appreciated. Your help thus far has been absolutely incredible! I have joined and gym and started running - I'm feeling that great! Is there any way I can return the favor?

Thanks again!
B!

Feb 17, 2012
More Questions...
by: Wray

Hi B I'm so sorry, I forgot to mention B3 comes in two forms, niacin which causes flushing and nicotinamide which doesn't! The flushing is not dangerous, and it does open capillaries. Niacin reduces cholesterol levels, because of it's conversion to nicotinamide in the body. If you can't bear it, please get the nicotinamide. I remember a very funny incidence that happened to me. A friend being kind, mixed up a shake for me, and put in 1/2 tsp! Well I had to lie down for about 3 hours while it wore off, I looked diseased! If you find the tyrosine is not doing much, increase the amount. Just do this slowly as too much can cause the very symptoms it's being taken for. When this occurs, reduce to the amount you were taking, and that should be continued for a few weeks. Another prolactin test will reveal if it's helped and you can stop it. You say the pain behind your eyes has been worse in the last 2-3 weeks, is this since increasing the progesterone? If so then it is related to excess oestrogen, as increasing progesterone also causes oestrogen dominance symptoms. Do let me know. And have you increased higher than the 100mg/day you were using? As I really believe you need more. I also hope you're rubbing it everywhere, and not just on the thin skinned areas!. I would hope with time that your scalp will heal, and stop producing so many dead cells. Both vitamin D and progesterone are the most potent anti-proliferating substances. One reason they help psoriasis, which is nothing more than cells proliferating excessively. I mentioned hair follicles absorbing the progesterone well. Please consider a strange suggestion I have! One weekend, when you have no visitors, massage the cream into your scalp. Then wrap a very hot wet towel round your head, taking it off when cool. I've no idea if this will help, but I do know rubbing pure vitamin E into the scalp, plus the hot, wet towel, helps a dry scalp. I also know rubbing the progesterone directly on to any painful, achy or wounded area it works much quicker. I also have a male friend who uses the cream as a hair conditioner! I'm so happy you're feeling so much better! And bless you for offering to help, all I would ask you to do, is tell people about vitamin D and progesterone. There are too many people suffering needlessly, and all for a want of vital nutrients. Take care Wray

Feb 17, 2012
Coconut Oil
by: CamperKat

RE: the "cradle cap" psoriasis issue...consider using coconut oil. It has anti-bacterial qualities and super-moisturization properties. I think you will find that if you rub it into your scalp every night for a couple weeks, probably less, that you will have significant reduction of your "dandruff"--if in fact, it is not cured. Also...you must avoid all shampoos that have lathering sulfates in them--these are detergents that strip all your natural oils, and your body then tries to compensate by making more sebum/oil and that can cause sloughing skin issues such as you are experiencing. RE: shampoo brands--I've tried the all for my husband who had a similar issue as you--and suggest the Jason brand dandruff shampoo--non-lathering, works great. Alternate the Jason shampoo with the "Beautiful Curls" brand of shampoo/conditioner, with shea butter and coconut oil. They make 2 kinds, the "enhancing" and "activating" variety--get the "activating"--much more moisture. The conditioner is "leave-in"...I didn't want to risk leaving it in--and the stuff was great just as a rinse-out, but I now use it as a leave in after I shampoo/condition, and use it on the midshaft-down of my hair. Beautiful Curls also makes It's available at Whole Foods and on Amazon. It's made for African Americans but we are White and we use it--my husband has straight hair, I have slightly wavy--and this stuff is a god-send...all natural--and I mean ALL NATURAL ingredients--and super-moisturization without grease and no silicones. Amazing stuff, incredible for the scalp and hair. I can't sing the praises of this stuff enough, because I have spent hundreds trying to find an all-natural product that can moisturize without stripping or being greasy. Note it contains magnesium sulfate--but this is not the lathering kind of sulfate...in this use, it contributes to hair body. Anyway, Beautiful Curls shampoo and conditioner costs about $10 for each 12 oz. bottle.

I've been using it for about a year now, for all moisturization/hair/cooking needs. The eczema on my elbows/knees is gone, my hair looks much healthier, and coconut oil makes a killer fried chicken--and NO I don't eat a lot of fried foods, but I used coconut oil for everything I cook.

Also...I'd do what Wray suggests--use Natpro on the scalp, and then alternate it with the coconut oil--obviously use Natpro during the day, and maybe sleep with the coconut oil on your head wearing a winter ski-type skull cap.


Feb 17, 2012
Coconut Oil / Part 2
by: CamperKat

continuing on...

You can get coconut oil at most grocery stores--get the kind that is virgin, cold expressed/pressed and not refined. It looks like Crisco when it is cold, and like liquid oil when it is warm. Needs no refrigeration, can stay on the counter year 'round and will be fresh for up to 3 years--remember, it is a tropical product. As you may know, it is a medium-chain trigylceride, actually thermogenic--which means that although it is "saturated", it is a good happy fat--it helps your body burn fat.

The Whole Foods 365 brand is $9 for 15 oz. Oh--and you can eat it, too--and use it instead of all other oils for your cooking needs. It really is remarkable.

And the positive about alternating it with Natpro is that it absorbs so quickly into your skin that you don't really have to worry about washing it off before applying Natpro.

Good luck!

Feb 17, 2012
Probiotics
by: CamperKat

Forgot to tell you this...after much nutrition research over the past year, I've learned a great deal about "real" food, vitamins, supplements, fiber (grains are really REALLY bad anti-nutrients--get your fiber from veggies and fruit only)...and...guess what has now been proven to be an effective cure / reducer of auto-immune disorders like thyroid/Hoshimoto's, rheumatoid arthritis, eczema, Crone's, IBS, etc?

Probiotics.

Yep. Remember the old saying "listen to your gut"? None of us did--we listened to the USDA/FDA etc. instead, telling us to eat whole grains (grain products are subsidized by the government) for our digestion--which absolutely destroy the good flora in your gut--and which block absorption of all that calcium, iron, magnesium etc. we've all been taking for our bones.

Grains contain phytic acid, and the indigestible insoluble fiber in grains causes inflammation in the intestines, resulting in bloating, gas, pain, and an inability to absorb nutrients. The U.S. has the highest per capita consumption of grains and dairy products--and the highest rate of osteoporosis. Grains block nutrient absorption, unless they are sprouted prior to consumption, which releases the phytic acid (phytic acid is what causes grains to grow) and when was the last time you ate sprouted oatmeal? Archeological studies of neolithic man have shown the bones and teeth of agriculture (grain growers/eaters) societies were shorter and more brittle and cavity-ridden than that of paleolithic "cavemen"--who did not have the grinding technology to create edible grains, and who subsisted only on meat, fish, vegetables, limited fruit and very small amounts of some nuts and seeds.

(cont'd)

Feb 17, 2012
Probiotics/ Part 2
by: CamperKat

cont'd

Anyway...to get your guts working again, to reduce inflammation and to absorb the nutrients your body needs to fight auto-immune disorders, take probiotics. Probiotics are bacteria that your intestines need to digest food--this is what you need, not grain fiber.

Do your own research--go on the internet, type in "probiotics arthritis" or "probiotics eczema" and watch what turns up. Real studies (I don't have time to post links now, if you're interested, let me know and I'll forward the links) show that in a 2 month study, rheumatoid arthritis sufferers had a 28% reduction of pain and inflammation levels. The study only lasted 2 months, but if they'd had the funding to go longer, they'd be able to post the follow-up results: after continuing probiotics for a total of 6 months, rheumatoid arthritis symptoms and blood markers had returned to near normal levels. Inflammation is systemic--that's why people who have bowel disorders almost invariably also have other issues like fibromyalgia, rheumatoid arthritis--or "milder" things like chronic joint pain (me).

So...after much research, I started taking probiotics...powder form, the refrigerated kind, a brand that has multi-types of bacteria that make your guts function properly, so you can absorb nutrients, reduce inflammation. I take Nature's Way Reuter, about $17 at Whole Foods or online at Amazon. It says to start with 1 teaspoon--that's a lot. I started at 1/4 teaspoon, mixed in with cool water (heat kills bacteria) and you MUST TAKE ON AN EMPTY STOMACH because digestive acids will kill the probiotics. Wait an hour after taking the powder before eating. You'll have some minor flatulence for a couple days, but your bowel movements will start to go like...smooth moves! No kidding, you start to get action quickly. After 5 days, increase to 1/2 teaspoon per day, then after another 5 days, go to the full 1 teaspoon.

Inflammation, joint pain, eczema, thyroid issues will start to abate one by one, with skin being the first to improve, joint pain second...takes about 3 weeks to start to see a marked difference. Keep taking it, do not eat those horrible inflammatory--and enjoy your life!

Good luck!

Feb 17, 2012
Bad Day. : (
by: B!

Wray:

I was anxiously waiting your response. Thank you for getting back to me so quickly! You made my day. And, trust me, I've needed a little sunshine today.

The eye pain is occuring almost every day. And, today the joint pain reappeared. I started my period on Wednesday. Typically, I have a 5-6 day period and it seems to have basically stopped. Also, I am experiencing horrible mood swings and irritability. I've turned into a mean lil' devil! The trouble is, I am completely aware that I'm being unreasonable and mean. I tell me brain to knock it off but yet I can't stop being mad. Then, of course, I want to cry.

I have struggled putting more than 100 mg of the cream. I've already gone through one jar and am stressing with the amount of money its costing (in addition to all the supplements). But, if you think it is absolutely necessary, I'll do it. I can't take the grumpiness and really want to get better. I will be honest though. I had the passing thought tonight of just quitting because this is hard. I don't know how I can feel so great one day and then so very bad the next. And, while I have been feeling better, I do still have some grumpy moments...but nothing like today.

Who knows, maybe I'm just a grumpy person? But, I don't feel like that is who I am and it upsets me that I have no control. This is something that has bothered me for some time. Typically, around ovulation women are supposed to be happy and desire intimacy. I seem to be the exact opposite. In fact, I am typically so grumpy that it is the last thing I physically want to do. I feel this is hormone related because I want those things but the feelings never arrive and the only thing that appears is a bad mood. While my husband is very patient, it's not fair to him or to me.

I don't know, maybe this is all too personal but I feel like quitting. I need some encouragement and you're the only person that I know I can reach out to who has experienced something similar. No pressure, Wray. ; )

Thanks again.
B!

Feb 18, 2012
Don't Give Up!
by: Mrs. A

Hi! I wanted to come by and give you a big hug!! I see this as the storm before the calm. It will get better. I also wanted to tell you that you are not alone with the concern of costs with treatment. I am on a bunch of supplements and have been since my son was born and all hell broke loose with my health. For example, if I don't take my adrenal glandulars, I will end up in ER. The doctor's haven't been able to help me. I also couldn't chew my food during the follicular phase and I couldn't walk (myopathy). The glandulars cost me lots of money and now I'm on the progesterone cream I am really broke BUT I have my health back. It is not 100% but it is enough that I can walk for miles, I have my strength back and I have more happy days than depressed days.

Please keep going with this! You will only have to pick yourself up again if you quit on your program now. I know how you feel about the expenses. I have had to sell a bunch of things on eBay recently to pay for my cream! I'm dead serious about getting better. It is possible (of course we can't be sure) that over time you can decrease some supps and even the cream. You just need to get over the oestrogen dominance 'hump' and a lot of wheels and cogs will start turning for the better in your system.

Please let us know how you are doing and feeling. I am subscribed to your page so I can keep in touch and follow your progress.

With love!!

Mrs. A
xXx

Feb 18, 2012
Bad Day. : (
by: Wray

Hi B I'm sorry to hear you're having a bad day. Don't give up, it really is worth it, and as CamperKat said in the beginning, it can take time for things to balance out. You've only been using the higher amount for about a week, if I'm right. Plus I don't believe it's enough. I'm going to do something I never do, and that's suggest you try the Natpro. It's a cream we make, and looking at the comparative costs of the creams, to get the 2000mg progesterone in a tube of Natpro, via the cream you're using, it would cost you $51.98, Natpro is $23.00 for the same amount. It is not sticky either. I say I never do this, as it's up to the individual what cream they use. It contains double the amount of progesterone per gram of cream, so you will be able to afford the higher amounts we all suggest. The early days are very bumpy! So please hang in there, and of course you're not a grumpy person, you certainly don't come over as one! You've mentioned something you hadn't before, and that's feeling totally unlike having sex before ovulation. We do normally feel more sexually aroused then, and the reason is not the rise in oestrogen, as we're lead to believe. But progesterone. About 50 hours before ovulation, there is a pre-ovulatory surge in progesterone. This surge comes from the brain, see here, here and here. It's now thought that this surge is responsible for the LH surge, which in turn causes ovulation. Without this surge it appears we won't ovulate, which of course means we won't make progesterone during the luteal phase, when oestrogen also rises. As the surge rises it causes a drop in pre-ovulatory oestrogen levels. We do have a Graph which shows the rise and fall of the hormones. We do have to alter the graph slightly, as it doesn't show this pre-ovulatory rise. It appears you are not getting this surge, or one too low to counter the high oestrogen that occurs prior to ovulation. Please consider my suggestion of using the progesterone daily for 2-3 months. I would hope this will sort things out, plus suppress any excess oestrogen. Continued below.

Feb 18, 2012
Bad Day. : ( Part 2
by: Wray

Hi B I'm sorry I forgot, but there's another thing I should have mentioned when you said your libido was non existent. I did tell you high prolactin suppresses dopamine, well dopamine is essential for a normal sexual response. If dopamine is low, so will be the libido. Progesterone does increase dopamine, it also suppresses prolactin. Please continue with the tyrosine, and the vitamin D. The rate limiting step in dopamine synthesis is the enzyme tyrosine hydroxylase. Insufficient levels of vitamin D inhibit tyrosine hydroxylase, resulting in a disturbance in the dopamine pathway. Please have a vitamin D test done soon, as you might have to take more than the 10,000iu's you're currently taking. Incidentally tyrosine is essential for any stressful situation, cold, fatigue, emotional trauma, prolonged work, sleep deprivation, it improves memory, cognition and physical performance. These are some papers on dopamine and the sexual response, see here, here, here, here, here and here. Most seem to be done on males, as if women had no sexual urge, or dopamine! One paper mentions allopregnanolone, this is a metabolite of progesterone. And is potent anxiolytic, anti-inflammatory and analgesic. Interestingly low levels have been found in women with PMS the few days prior to bleeding. Another interesting fact, stress causes a drop in libido, simply because dopamine levels drop. So of course do progesterone levels, which would affect dopamine. Stress also drops vitamin D levels too. I love the patterns in the body, you can't look at the parts, you have to look at the whole, see here. The info CamperKat has given is invaluable. She was on a cocktail of drugs which caused her to put on weight and feel awful, until she started researching what the drugs were doing to her, plus the 'good' foods she'd been told to eat. If you want to read her journey, please put her name into the google search bar. Write in any time you need. Take care Wray

Feb 18, 2012
Don't Give Up!
by: Wray

Hi Mrs A Bless you for this, it's the best medicine, someone else's caring thoughts. CamperKat has given her wonderful advice too. Take care Wray

Feb 18, 2012
Coconut Oil
by: Wray

Hi CamperKat Thanks for the wealth of info! I'm also a fan of coconut oil. I also use MCT oil which is a fractionated oil from coconut oil. It comprises 60% caprylic acid and 40% capric acid, caprylic acid is an excellent anti-fungal. I prefer the oil to the tabs, far more effective, and it can be applied topically too. Plus it can also be used for cooking, making sauces, makes a particularly good mayo, very light with no flavour. So I add a touch of olive plus herbs etc. And I use it on all my foods in place of olive oil. Does have a slight laxative effect which is often needed by many. It can be burnt as an energy source by the cells much as carbs are, but without the damaging affect these have, and does not get deposited as fat. Your info on the probiotics is so good too. We don't realise how important they are, and as so many now take antibiotics, most people don't have many good ones left! Take care Wray
PS When I read your info, I asked the webmaster if we could have a contributions field on our nutrition page, as I wanted to put what you'd written on that. Well I've just received confirmation it's been done! So I will be copy/pasting your info there too.

Feb 18, 2012
Yes to that!
by: Mrs. A

I'm also taking probiotics and I like to use coconut oil. I use Tiana's coconut oil (and coconut flour which is yummy) and have just started on Custom Probiotics CP-1 Adult formula. I will use coconut oil more after reading what Camperkat wrote!

Oh! By the way, in my previous comment, I meant to say 'luteal' phase not follicular! I used to crash badly in the luteal phase.

There is a great book called 'Why Do I Have Thyroid Symptoms When My Lab Tests Are Normal?' by Dr. Datis Kharrazian. In particular, I like the info he has there on the gut/probiotics connection to thyroid function and hormonal imbalance, blood sugar and the inflammatory response. That really shook me up about probiotics. Something like 20% of T4 to T3 conversion happens in the gut and you need the 'good guys' in there to help that happen, so with a good probiotic your thyroid will improve quite a bit! I know I feel WAY better when taking a good quality probiotic.

Love to all!

Mrs. A
xXx

Feb 19, 2012
Yes to that!
by: Wray

Hi Mrs A Thanks for the book reference. Sounds like one we should all have! The confusion over thyroid issues is immense, never once are iodine, selenium or tyrosine ever checked. And yet without these no T3 or T4 will be made. Stress plays a huge role too, that's not looked for either. That's another page I have written, but not up yet! Take care Wray xxx

Feb 20, 2012
Many thanks to all...
by: B!

Wray, CamperKat, and Mrs. A:

Thank you so much for the information! The words of encouragement are reassuring and it is especially nice to know that some things I am feeling are normal and/or expected considering the circumstances.

I increased my dosage to 160mg as of Saturday. I am feeling a little better but still sort of blue.

Also, I increased the Vitamin D to 15,000ius and the l-tyrosine to two pills.

I have been rubbing the cream everywhere. I am going to finish the two bottles of cream I purchased and switch over to Natpro as suggested. I’m not a big fan of being sticky.

I will try the coconut oil on the scalp. I actually have some but have mainly been using it for cooking. Has anyone happened to try it with a bit of organic dark chocolate? It’s a really nice treat!

I have removed all non-organic beauty products and limit exposure to non-organic foods. The removal of grains and dairy has been really hard, especially in the beginning. I did that for a year or so, supplemented with heavy dose probiotics and saw major improvement. The real progress began with I started the HCL tablets. I had a blood test performed, which revealed far too many proteins in the blood. Apparently, I was not digesting my food properly and had a major candida problem.

I did the probiotics, HCL supplements, a yeast cleanse, and a 35-day juice fast over the course of 8 months. I am off all meds and my symptoms have decreased but I do not feel as great as I should. The quest for wellness has been a two year project and cost me a small fortune.

I feel like I do a lot of great things and that I am ultimately on the right path. I think I get frustrated because I haven’t come full circle and still struggle with lingering symptoms. And, while the symptoms are small compared to where I was in 2010, they are still huge things in the background. When I experience a setback (like now), I feel completely lost and hopeless.

I am over here throwing myself a pity party. I suppose I just need to embrace the increase in oestrogen. So far, I’m not a big fan of the symptoms. My weight is up and my mood is down. Since I started the cream, I am up 5 pounds and it’s all in my hips and butt. But, on a positive note, I do have better energy and my psoriasis and vitiligo have improved dramatically. My motto needs to be: take the good with the bad. I have laxed on the probiotics, but I suppose it can’t hurt to add those back in as maintenance.

I just want you all to know your advice has been invaluable to me and I truly thank you for taking the time to respond with your recommendations. I will heed your advice and put the money worries aside.

Thanks again for all you do. I feel so self-absorbed with this posting. I hope one day I can help women the way you continue to help me. I look forward to the day when I can see past my own issues to counsel others!

Best wishes!
B!

Feb 20, 2012
Sweating
by: B!

Ladies:

Maybe you can help riddle me this. : ) I forgot to mention another embarassing yet annoying symptom that has never been addressed. Excessive sweating! I sweat all day! And, it doesn't matter what type of under-arm deodorant I use. I don't experience any other sweating or flushing, just my under arms. I have had this for as long as I can remember and it's horribly embarassing because it's quite obvious! I typically have to wear dark clothes because of the stains.

Does anyone know what this is about? I have noticed some days (since starting the cream) it is much better but then other days, it doesn't make a difference. Maybe I'm missing another key element? Or, is this another one of those lovely oestrogen dominance symptoms. : )

Feb 23, 2012
Many thanks to all...
by: Wray

Hi B So pleased things are looking slightly better, you certainly generated an immediate reaction from us! All of us have been through tough times, and all have finally come out the other side. So take heart, besides you seem to have been doing so much to help yourself, and you say you are far better than you were. It takes so long but worth it in the end. So delighted the psoriasis and vitiligo have been helped so much. These two are more than enough to make anyone despondent. CamperKAt has such good things to say about the probiotics, it wouldn't hurt to add them again. Having been through a tough time, does make one more empathetic with others. I look back on my life and wonder why, but it's stood me in good stead now. You might like to see this page on Hyperhidrosis, and here too. One of the possible causes is an increase in the sympathetic nervous system, which is basically our fight/flight system. Progesterone is calming, so this could account for the days when it seems better. It could be related to low vitamin D, who knows, it would be wonderful if it was. Please have a test done soon to check how high your level is, it could be you need to take more. Dr Cannell has found with his autistic patients he needs to take the level to 150ng/ml before they get well, then he reduces back down to the 80-100ng/ml range. Autism is another of those 'autoimmune' diseases which are on the increase, and he's firmly convinced it's just caused by a lack of vitamin D while a foetus. You don't mention any smell from the excess sweating, but if it is bothering you it could be because the pH of the underarm is too high. The skin has a pH of 4.5 to 5.5, it can be slightly higher in the underarm. But if too high, bacteria have a field day. The pH can be checked using acid/alkaline strips from a health shop. If too high various natural acids like vinegar, lemon juice, citric or tartaric acid, would bring it down. Add a small amount to some water and rub this on your underarm, it might help. Test a little to make sure it doesn’t sting. The arm pit has two sweat glands, eccrine which produce what we know as sweat. And apocrine which produce a thick secretion containing cholesterol, hormones, fats and protein. This is apparently only produced in response to emotional stress. But from correspondence I've had, I believe it could also arise from our hormones being out of balance. Although it has no smell, bacteria living on the skin break it down with enzymes releasing an odour. The offending substances are fatty acids and the androgen steroids, especially 5-alpha androstenol and 5-alpha androstenone. These androgens are pheromones found in human sweat glands and urine. The enzymes the bacteria secrete are beta-glucuronidase and aryl sulfatase. Continued below.

Feb 23, 2012
Many thanks to all... Part 2
by: Wray

Hi B Steroid malodour production can be prevented by inhibitors of beta-glucuronidase and aryl sulfatase. Oestrogen and the androgens are metabolised in the liver by glucuronic acid, the process is known as glucuronidation. The process also removes other substances, including toxins, drugs, bilirubin, mineralocorticoids and glucocorticoids. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase breaks the steroid/glucuronide bond, which allows the steroids to be reabsorbed. Calcium D-glucarate inhibits beta-glucuronidase. I don’t know what inhibits aryl sulfatase. So I suggest taking some calcium D-glucarate and see if that helps. Incidentally this enzyme is produced by undesirable gut bacteria, supplementing with probiotics suppresses the bacteria, and subsequently the beta-glucuronidase. Do avoid all the aluminium based anti-perspirants. Take care Wray

Feb 23, 2012
Sweating
by: B!

Thanks, Wray. The sweating does not cause an odor (thank goodness for that). ; ) I will try the PH trick and see if that helps.

This weight gain is starting to get a little out of control and my pants are no longer fitting the way they should. Eeekk! I really do not want to go purchase new clothing.

Since this is all oestrogen dominance related, do you think it will be helpful to do a detox? I figure maybe doing a juice detox with a concentration on the liver might help me get rid of the excess estrogen faster. Also, maybe adding some milk thistle?

I am getting ready to order a hormone check to see where I am at. Do you think this is a waste of money since I am in the beginning treatment or should I just go for it? Also, I am going to order the D3 to find out there I am. I think last year I had a score of 13.

If you think the detoxing cleanse will help rid the excess estrogen, perhaps I will wait to do the test.

As always, I look forward to your thoughts.

B!

Feb 24, 2012
Sweating
by: Wray

Hi B Well I'm relieved for your sake there's no smell. The pH trick is really for smell too, I don't know if it would help excess sweating. A juice detox is always a good idea, provided it's mostly veggies and fruits with not too high a sugar content, apples are good. Milk thistle is excellent, it goes into every one of our complexes. The liver does it's best, but now it has so much more to contend with, with all the toxins we inadvertently consume. We can't avoid them now. For instance there are over 100 oestrogen mimics in the environment, see Our Stolen Future. Never mind those in our food, air, water, skin care, particularly sunscreens, household and industrial chemicals! You might like to see our Nutrition page. There are links to sites giving excellent advice on food, plus raw food. I wouldn't spend money on a hormone test yet. One thing it will say and that is your progesterone is through the roof and you must come off it! One women who still has oestrogen dominance symptoms has a P:E2 ratio of 9700:1! Admittedly she is using 420mg/day progesterone as anything less was not helping. But it is now after 6 months of increasing the amount to the 420mg/day. So far she has been unable to follow her cycle, as every time she tries her symptoms come back. A vitamin D test though would be an excellent idea. Do you know if your vitamin D was tested in ng/ml of nmol/L? As you live in Canada, probably nmol/L, which means it is/was dangerously low and it doesn't surprise me you have all those 'autoimmune' problems. The Ca D-glucarate also helps get rid of excess oestrogen, probiotics you know about and said you were adding them back. Take care Wray

Mar 01, 2012
Update
by: B!

Wray:

You have been instrumental in my success so I thought I would stop in to let you know that I am doing pretty swell. My energy is up and my emotions are stable (thank heavens for that)! My libido is still missing but I suppose that will come in time...

I have been using the cream for almost a full month now. I am on day 16 of my cycle and from what I can tell, I did not ovulate (which I guess is to be expected?). I am experiencing breast tenderness and now hemorrhoids. Maybe this is a possible side effect to the liver - guess time will tell.

I am concerned about using the cream on a full time basis. Do you think I should finish up until about day 28 and then stop? I feel if I prevent my body from ovulating (by taking cream all month long) - I will not be producing progesterone on my own for the second half. I wouldn't mind having the process take a little longer but whatever you recommend - I will do.

As always, I look forward to hearing from you.

Mar 02, 2012
Update
by: Wray

Hi B I'm so delighted! And thanks so much for letting me know, the others will see this too. And give it time, the libido will return. Have you tried the tyrosine yet? You said you had high prolactin, this depresses dopamine which is essential for a normal sexual response! Tyrosine is the precursor to dopamine. Ovulation will come, but you have to heal first. Try rubbing the cream on your breasts, this can help. But sore breasts can be caused by lack of iodine, see here, here, here, here, here and here. An easy way to find out if your level is low is to get a tincture of iodine. Put 3 drops anywhere on the inner arm, rubbing them in with the dropper. If the patch fades in a few hours it means there's a deficiency. Continue applying it until the patch takes days to fade. Or take a supplement. Also apply the cream to the haemorrhoids, it does soothe and often they go. You can stop the daily routine any time you wish, there's no hard and fast rule. I was just concerned you seemed so short of progesterone, and using it daily ensures it becomes dominant. Maybe it has with you, try it and see. If symptoms come back you know you haven't used it long enough. And you have only been on it for a month now, not long in the scheme of things, as you are luckily only 28! And are you taking vitamin D? Please let me know how the Hashimoto’s, Angioedema, Vitiligo, and Psoriasis are, I can't believe you have all those together. Did you have a vitamin D test done, I can't remember. Please do if not. Take care Wray

Mar 03, 2012
Updated continued...
by: B!

Wray:
You are a genius! Really, I am so blessed to have such a wonderful person helping me along my journey.

I realized, I never responded to you about the Vitamin D. The test done last year was in ng/mL (it was 14). I am planning to have it tested here in the next few weeks. I have an appointment set up (my guy travels the state so it’s always about timing).

I did start the tyrosine. I have been taking 1500 mg along with 800 mc of Folic Acid. Mood wise, I feel much better. I am still having a nipple discharge, which for me, was the main indicator that my prolactin was too high. I am hoping this goes away with time.

I am definitely going to look into the iodine! I was reading those research links you gave me and there is so much to me in that stuff (especially the low stomach acid part)! I have been using the progesterone cream – putting it on my breasts and have seen no difference in the cysts. Maybe iodine will be the trick. That would be so nice if it is – I hate those things!

Is it possible I am experiencing breast tenderness because I did not ovulate? I am concerned about being off my cycle because if I do not ovulate, I will not create my own progesterone during the second half of the cycle. I feel as if I should try to get back on my cycle and see how I am producing on my own. I will stick with it until day 28 and see if my period starts as normal. Then, stay off for 14 days and see what happens.

I have been continuing with the Vitamin D and I cannot tell you the difference this has made with my skin conditions. I would say the Psoriasis has disappeared and the Vitiligo is so much better. I dare say I may even be getting some pigment back. I did just add a topical vitamin d-3 cream to concentrate that one area as of yesterday.

My friends Hashimoto and Angioedema are on vacation from what I can tell. I haven’t had any episodes of them in almost 8 months (this has mainly been done through diet).

Today is my liver flush day. I am so excited but so nervous too! Have you ever done one?

Mar 03, 2012
Updated continued...
by: Wray

Hi B OMG! 14ng/ml?! No wonder you are feeling so bad, no wonder you have those 'autoimmune' problems. And no wonder you are responding to the vitamin D. Do let me know your level when it's tested. So pleased the tyrosine is helping your mood, I hope soon with the discharge, it does take time, all these nutrients do. If the progesterone is not helping the breast cysts then in all probability it is lack of iodine. Thank you for reading the links, I don't think many do! And no the tenderness is not from not ovulating, the amount of progesterone you're using will be more than enough to compensate for that. And don't be concerned about making your own progesterone just yet. But if it stresses you, try stopping and take heed of symptoms. I feel it's too soon, so I will be interested to hear from you. I'm so happy the psoriasis seems to have gone, and the vitiligo appears to be going. It's so interesting you tried a vitamin D cream on your skin, I make one too, and would love to get it on the web, one day! I would love to know if you find it helps. So delighted your other 'friends' have gone, hopefully never to come back. One thing I forgot to ask is how is the eye and joint pain, you said the eye was very bad. I hope by you not mentioning them they've also gone. And one final question, how is the sweating? And yes to the liver flush, I think once is enough! I will be interested to hear your results, nothing much happened to me, no stones. And bless you for the kind words! Take care Wray

Mar 07, 2012
More Progress....
by: B!

Hello there, Wray. I hope you are well.

I thought I would stop in and provide another update. The liver flush went well. I got over 100 little green stones out my first attempt. I am going to try another one in a few weeks.

The eye pain is around but I think I am figuring it out. During my liver detox/flush, it came back full force. Apparently, eye pain is a symptom of liver distress as is shoulder blade pain (two things I am experiencing right now). I am hoping that once I stop the supplements it will go away. But, I also think another flush might be helpful as well. Oddly enough, I can get rid of the eye pain with accupressure (I love researching this stuff)! So, at least I have that. I definately think it's tied into the liver distress.

All in all, things are doing pretty swell. I'm feeling good and I truly think things are getting better. I suppose the breast discharge and repigmentation will just have to take time. I am continuiing with the cream on a daily routine for the time being.

As a side note and totally off subject. My father-in-law passed away in November and my husband has been really depressed (naturally). Anyway, I remembered the l-tyrosine was supposed to help with dopamine. That has really seemed to help him. Plus, he has had incredibly bad insomnia for as long as I've known him. He has actually slept through the night two nights in a row. What are your thoughts on this - coincidence or another mystery solved?

Anyway, don't want to monopolize your time but just thought I would check in. Hope you are enjoying your week wherever you are.

B!

Mar 09, 2012
Argh!
by: B!

Hey there, Wray!

This is what I get for bragging about all my progress! lol

For the past two days, I have been experiencing very minor joint pain. I was hoping if I ignored it, I could pretend it wasn't really there! : ) Anyway, I also started having night sweats two days ago, as well. Then, oddly enough I started my period this morning (which is about 6 days early). I suppose this is probably to be expected but I am confused by the night sweats (and the joint pain). I have been sleeping so soundly (and dry) so I am bummed to see this happening again.

Do you have any thoughts on why this might be the case? I am still using the 160 mg of cream. Do you think maybe I should increase it to 200 mg the week before my period to see if that might help keep these symptoms at bay?

Mar 10, 2012
More Progress....
by: Wray

Hi B I went away for two days, and even though I always take my computer, I fall behind! I'm pleased the liver flush went well. One thing I forgot to tell you was to take taurine. This is vital for bile production, insufficient taurine lowers bile production and fats can back up in the liver. It's best to start it a week or so before the flush so you get a good amount of bile flowing. About 500mg/day up to 5000mg/day, it's very calming too. Interesting you found a connection between the pains and liver, don't forget milk thistle too, as this helps the liver detox, up to 420mg/day silymarins, the active ingredient. You were quite right about the tyrosine too, it's essential for any stressful situation, cold, fatigue, emotional trauma, prolonged work and sleep deprivation. And he's been deprived for a long time it seems, plus the drop in dopamine causes depression. So pleased it helped him. Brilliant move on your part! The pain is a natural result of your cycle. You say it came right before your period, don't forget oestrogen also rises in the luteal phase, so evidently you aren't using enough progesterone those few days before. Not that you knew you would bleed so early, makes it a trifle difficult working it out! The pain, night sweats are the result of excess oestrogen. So next cycle try increasing it the few days before, if you know when it occurs of course, and it doesn't catch you by surprise again. Try the 200mg and see if that helps, increase further if not. Any time you feel adverse symptoms coming back, know that the ratio of the two hormones has got out of balance. So increase the progesterone, always sticking to the optimum amount, ie the 160mg, when things are 'normal' and not reducing below this. Let me know how you get on, and I would really like to know how your husband fares. The amino acids fascinate me, the most remarkable healers. Remember too much tyrosine can cause the same symptoms it's helping with. If this should happen, just reduce the dose slightly. Take care Wray

Mar 14, 2012
OOOOOHHHHHHHH
by: B!

Well, well, well. I don't know where to start.

My menses finished up yesterday and I am still experiencing all of my pains. The joint pains have come back full force, as well as the night sweats. The eye pain is still occassional and bothersome. Plus, I now feel like I got hit by a truck. I am exhausted (in part because I am now not sleeping well). First order of business is taking a nap when I get home!

I am utterly confused as to what is going on with my body. I gather this is probably estrogen dominance related, but I am now in the part of my cycle where that is supposed to be normal (estrogen naturally higher than progesterone). I have upped the cream to 200 and it doesn't really seem to make a difference.

I feel like I have exacerbated all of my problems. I am confused on what to do now. Do I continue to wait these problems out, up my cream again, or throw in the towel hoping my body can regulate on its own? Prior to starting the cream, I was only having occassional pains here and there for a few days, but now I am getting them to where they last for weeks at a time (and they disappear for weeks at a time). This is so frustrating.

Help me, Wray. What do I do now? Maybe you can help explain why I am so out of balance in the first part of my cycle. I'm confused. :(

Mar 17, 2012
OOOOOHHHHHHHH
by: Wray

Hi B I'm so sad you've had this set back, it is confusing. Firstly, you are taking 10-15,000iu's vitamin D, if magnesium is lacking it shows up as pain. Please consider taking some, this might be the cause. The other of course is excess oestrogen. It does drop when we start bleeding, but sometimes it's still higher than normal and this would cause problems. It begins rising again 4-5 days later. I know you feel like giving up, so many do, but please hang in there. It has helped you in some ways, when reading back through your posts. It's only a month since you increased the progesterone to 160mg/day, you also said "When I experience a setback (like now), I feel completely lost and hopeless." It was only a week ago you thought of increasing to 200mg/day. You might take encouragement from these comments here, here, here, here, here, here, here, here and here. I feel once your vitamin D is up high, and your oestrogen low/progesterone high, you will get relief. But I also understand if you don't want to continue. take care Wray




Apr 20, 2012
Results...
by: B!

Hello, there Wray.

I wanted to post a status update on my progress. I did some additional research and had some other tests done.

I am happy to report that my Vitamin D results came back on the high side of normal so I have reduced the amount of Vitamin D supplementation.

Some time ago, I came across a website talking about the sodium/potassium ratio and its impact on estrogen and progesterone, as well as PMS. After reviewing 3 months of charting, I concluded that I was having major forms of PMS on particular days. The progesterone cream didn’t really seem to be making significant difference in my symptoms – they still kept appearing. After doing some leg work, I decided to have a mineral analysis performed to check these levels, as well as my calcium. The results showed an abnormally low sodium potassium ratio which, based on the research, was showing times of struggle during the particular times of the month that I was experiencing.

So, oddly enough, I have been adding lots of potassium to my diet and it is remarkable the difference! Low potassium can cause dry eyes and eye pain. Every time my eye starts to hurt, I eat a banana and the pain is immediately gone. I still am experiencing bouts of crankiness but it is dramatically improved and I am not nearly as emotional – thank heavens! My symptoms at ovulation and menstruation onset are improved and I am hoping that with time they will be eliminated. I will keep you posted on this in the following months.

I wanted to post this for others to see because I think there is something to be said for having these particular tests done. For me, I wanted to figure out what was causing the hormone imbalance (not just treating it with the cream) and the minerals definitely play a role in that regard.

What are your thoughts on this subject?

Apr 21, 2012
Results...
by: Wray

Hi B I'm so happy you have reported back. I've been wondering how you were doing and even thinking of asking you. Very pleased your vitamin D level is now on the high side. I'm so delighted you thought of checking the sodium/potassium ratio. So many things can affect us, not least a mineral imbalance. Interestingly low sodium affects the adrenals badly, low potassium the heart, and you've found the eyes too. I never know where to start, beyond giving advice on the progesterone. I wish everyone could or would have these tests done, but it's either the expense putting them off, or indifferent doctors who will only run the standard tests. For instance I did mention to you a lack of magnesium causes pain. This is particularly felt if vitamin D is started. An imbalance between calcium and magnesium causes blood glucose problems, which can progress to diabetes. If they are at toxic levels, or very out of balance, severe depression can set in! Or high calcium can cause heart disease, see here, here, here, here and here. Copper and zinc work together, but high copper causes depression and psychosis. This can well be the reason for PMS and PND. Oestrogen increases copper levels, decreases zinc. Progesterone does the reverse. An excellent site to look at is Alternative Mental Health. This has many articles by various specialists, one in particular is William Walsh. He has specialised in biochemical individuality, particularly mineral imbalances. Continued below.

Apr 21, 2012
Results...
by: Wray

Hi B Most of the time I feel I'm walking blind folded through a maze! I never know what confounding factors could be affecting a person, the problem is they don't either. I was trying to help someone, who has given up and now thinks diuretics are the answer, the 'progesterone' caused her to retain water. No amount of reasoning or studies could dissuade her from this view. I then learnt in a round about way that the food she eats is her major problem. She saw someone on TV saying you should have no more than 3 tsp of sugar per day. This was a revelation to her! I had wrongly assumed she knew how to eat correctly, and that all sugar is bad and should be avoided. But I will in future ask people to have their minerals checked if they are having problems which progesterone is not helping with. So bless you for this coming back with this and reminding me! I am now going right back to a woman I answered today, who I've been trying to help with long standing PND, as now I feel she could have high copper levels. Thank you! Take care Wray

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