I am 41 and have 1 ovary. I have periods day 28-31. I have problems with insomnia, tender and enlarged breasts before a period. I am moody, anxious, cold hands and feet, thinning hair, etc. I am on Nature-throid as well for hypothyroidism. I tried this month 12.5mg over the counter progesterone cream, but symptoms did not go away. As a matter of fact, my insomnia is worse. My period did not come by day 31, so I asked my doctor about it and he said to take the cream for 3 weeks straight and then take off 1 week. I stopped taking it Monday and got my period Wednesday morning. I want to start natpro (you are currently out of stock), but when during my cycle should I start? I have read on your website to start day 14 or should I do 3 weeks straight? Do not want any more children, so does it matter if I ovulate? Please help because not sure what to do. Thank you!