I have Factor 5 Leiden
(North Saanich, BC, Canada)
I have just started taking Natpro and so far I have not noticed any changes eg. hot flashes reduced or feelings of edgyness or anxiety reduced or insomnia reduced, but since it says on the website that symptoms can get worse during the first 3 months, I will persevere.
What I am most concerned about is if the progesterone will increase my ability to clot because I have Factor 5 Leiden and already have a propensity to clot more than normal.