HRT Research Papers

BMJ 2010;340:c2519 Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study

AIM 2010 vol. 152 no. 4 211-217 Coronary Heart Disease in Postmenopausal Recipients of Estrogen Plus Progestin Therapy: Does the Increased Risk Ever Disappear?

ScienceDaily Feb. 19, 2010 Short-Term Heart Disease Risks of Combination Menopausal Hormone Therapy Confirmed

JAMA. 2009;302(3):298-305 Hormone Therapy and Ovarian Cancer

Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD001405 Oestrogen therapy for urinary incontinence in post-menopausal women

The Lancet, Volume 374, Issue 9697, Pages 1243 - 1251, 10 October 2009
Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial

Hormone Replacement Therapy and Cardiovascular Health in the United States. Medical Care:May 2009 - Volume 47 - Issue 5 - pp 600-606

The New England Journal of Medicine, Volume 360:573-587 February 5, 2009 Number 6
Breast Cancer after Use of Estrogen plus Progestin in Postmenopausal Women

Cancer Epidemiology, Biomarkers & Prevention March 2008 17; 614 Reproductive Steroid Hormones and Recurrence-Free Survival in Women with a History of Breast Cancer

WebMD Health News March 7, 2008 Estrogen Brings Breast Cancer Back

AIM Vol. 168 No. 4, February 25, 2008 Estrogen Plus Progestin and Breast Cancer Detection by Means of Mammography and Breast Biopsy

WHI FEBRUARY 2008 Hormone Therapy Increases Frequency of Abnormal Mammograms and Breast Biopsies

ScienceDaily (June 20, 2008)
Complex Changes In The Brain's Vascular System Occur After Menopause

Arch Intern Med. 2008;168(8):861-866.
Postmenopausal Hormone Therapy and Stroke
Role of Time Since Menopause and Age at Initiation of Hormone Therapy

Medscape March 11, 2008
Estrogen Levels Linked to Risk for Breast Cancer Recurrence

From Heart wire - a professional news service of WebMD March 5, 2008
Breast Cancer Risk Remains After Stopping HRT

ScienceDaily (Apr. 9, 2008
Estrogen Therapy Increases Benign Breast Disease Risk, Study Suggests

University of Oxford 19 April 2007
HRT increases incidence of, and deaths from, ovarian cancer

Environ Health Perspect 115:A297-A297 1 June 2007 Molecular Biology: Estrogens Shield Breast Cancer Cells.

NEJM Volume 356:1670-1674 April 19, 2007 Number 16 A sharp decrease in breast cancer incidence in the United States in 2003

University of Oxford 19 April 2007 HRT increases incidence of, and deaths from, ovarian cancer

Medscape Medical News April 24, 2007
Hormone Replacement Therapy Linked to Ovarian Cancer

Metabolism Volume 56, Issue 6, June 2007, Pages 830-837
Addition of medroxyprogesterone acetate to conjugated equine estrogens results in insulin resistance in adipose tissue

JAMA. 2007 Apr;297(13):1465-77
Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause.

The FASEB Journal 2007;21:2285-2293.
Disruption of androgen receptor signaling by synthetic progestins may increase risk of developing breast cancer

CANCERactive Published 2007
HRT increases cancer risk - confirmed yet again

CANCERactive Published 2007
Dramatic fall in Breast Cancer rates points finger at HRT again

JOURNAL OF CLINICAL ONCOLOGY
VOLUME 24 NUMBER 33 NOVEMBER 20 2006
Recent Declines in Hormone Therapy Utilization and Breast Cancer
Incidence: Clinical and Population-Based Evidence

Arch Intern Med 2006;166:772-780.
Postmenopausal Estrogen Use Linked to Elevated Clot Risk in Clinical Trial

Maturitas Volume 52, Issue 1, 16 September 2005, Pages 1-10
New evidence regarding hormone replacement therapies is urgently required
Transdermal postmenopausal hormone therapy differs from oral hormone therapy in risks and benefits

JNCI Journal of the National Cancer Institute 2005 97(8):595-602;
Plasma Sex Hormone Concentrations and Subsequent Risk of Breast Cancer Among Women Using Postmenopausal Hormones

Ann. N.Y. Acad. Sci. 1052: 152-169 (2005). The Future of Hormone Therapy: What Basic Science and Clinical Studies Teach Us The Case for Progesterone

Obstet Gynecol. 2005 November; 106(5 Pt 1): 940-945. Postmenopausal Hormone Therapy Does It Cause Incontinence?

Cellular and Molecular Life Sciences (CMLS)
Volume 62, Number 3 / February, 2005
Alzheimer's disease: the impact of age-related changes in reproductive hormones

Maturitas Volume 49, Issue 4, 10 December 2004, Pages 315-320 Effects of progestins on estrogen-induced increase in C-reactive protein in postmenopausal women

JAMA. 2004;291:47-53.
National Use of Postmenopausal Hormone Therapy
Annual Trends and Response to Recent Evidence

Biological Psychiatry
Volume 55, Issue 4, 15 February 2004, Pages 406-412
Lack of efficacy of estradiol for depression in postmenopausal women: a randomized, controlled trial

BMJ 2004;328:357-358 (14 February), doi:10.1136/bmj.328.7436.357
Where are we now with hormone replacement therapy?

Annals of Internal Medicine
3 February 2004 | Volume 140 Issue 3 | Pages 184-188
Changes in the Use of Postmenopausal Hormone Therapy after the Publication of Clinical Trial Results

Exp Clin Endocrinol Diabetes 2003; 111: 267-273 One Year Follow-Up of Hormone Replacement Therapy with Percutaneous Estradiol and Low-Dose Vaginal Natural Progesterone in Women with Mild to Moderate Hypertension

Maturitas. 2002 Sep 30;43(1):35-9. Effect of hormone replacement therapy on uterine fibroids in postmenopausal women--a 3-year study.

Medscape Dec. 15, 2003
Estrogen Plus Progestin Doubles Risk of Venous Thrombosis

The Lancet Volume 362, Issue 9382, 9 August 2003, Pages 428-432
Differential association of oral and transdermal oestrogen-replacement therapy with venous thromboembolism risk

The Lancet, Volume 362, Issue 9382, 9 August 2003, Pages 414-415
Breast cancer and hormone-replacement therapy in the Million Women Study

Cancer Causes and Control
Volume 14, Number 2 / March, 2003 , 195-201
Patterns of postmenopausal progestin use with estrogen in relation to endometrial cancer

BJOG: An International Journal of Obstetrics and Gynaecology
Volume 109 Issue 9 Page 1056 - September 2002
A study of hormone replacement therapy in postmenopausal women with ischaemic heart disease: the Papworth HRT Atherosclerosis Study

Clinical Therapeutics Volume 21, Issue 1, January 1999, Pages 41-60 Oral micronized progesterone