How can I stop my miscarriages

by Nazneen
(Maldives)

I got pregnant first in 2003. I lost my baby after 2 and half months. Secondly I got pregnant in 2007 this year. Again I lost my baby after 5 and half months.

Could you please explain to me why this happens?

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How can I stop my miscarriages

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Miscarriages
by: Wray

Hi Nazeen, Many things can cause a miscarriage, genetic factors, stress, depression, coronary heart disease, hypertension, type 2 diabetes and more. But a lack of progesterone is the most probable cause if the above have been ruled out. Progesterone is not only vital for the successful implantation of the embryo, but for the maintenance of the pregnancy. I have pasted info from some research papers for you. Do hope this helps. Take care Wray

"Thus, progesterone production at the placental level may be responsible, at least in part, for increased production of Th2-type cytokines which have been implied in fetal allograft survival and maintenance of successful pregnancy."
http://www.jimmunol.org/cgi/content/abstract/155/1/128

"Since a well-balanced interaction of nervous, endocrine and immune system is crucial for the maintenance of successful pregnancy, putative mechanisms and recent observations on stress-triggered pregnancy failure have been reviewed."
http://www.ingentaconnect.com/content/mksg/aji/2001/0000004
6/00000002/art00001

"Progesterone is efficacious when continuation of pregnancy is hampered by immunological factors, luteinic and neuroendocrine deficiencies and myometrial hypercontractility. This may explain the reduction in the incidence of preterm birth in high risk pregnant women using high-dosage prophylactic progesterone."
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1471-
0528.2005.00586.x

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Submitted by: Wray

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Hi Nazeen, Many things can cause a miscarriage, genetic factors, stress, depression, coronary heart disease, hypertension, type 2 diabetes and more. But a lack of progesterone is the most probable cause if the above have been ruled out. Progesterone is not only vital for the successful implantation of the embryo, but for the maintenance of the pregnancy. I have pasted info from some research papers for you. Do hope this helps. Take care Wray "Thus, progesterone production at the placental level may be responsible, at least in part, for increased production of Th2-type cytokines which have been implied in fetal allograft survival and maintenance of successful pregnancy." http://www.jimmunol.org/cgi/content/abstract/155/1/128 "Since a well-balanced interaction of nervous, endocrine and immune system is crucial for the maintenance of successful pregnancy, putative mechanisms and recent observations on stress-triggered pregnancy failure have been reviewed." http://www.ingentaconnect.com/content/mksg/aji/2001/0000004 6/00000002/art00001 "Progesterone is efficacious when continuation of pregnancy is hampered by immunological factors, luteinic and neuroendocrine deficiencies and myometrial hypercontractility. This may explain the reduction in the incidence of preterm birth in high risk pregnant women using high-dosage prophylactic progesterone." http://www.blackwell-synergy.com/doi/abs/10.1111/j.1471- 0528.2005.00586.x

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