Estrogen Dominance?

Hello,
I have a lot of symptoms indicating an estrogen dominance. When I went to my doctor and got a blood test to find out she did not really look at my estrogen dominance question that I had, but rather just looked at my results and told me that I'm not in menopause yet. My results were as follows: FSH 2.2, Progesterone 10.4 and Estradiol 140. I tried to do the calculations to figure it out myself and it appears that I may be estrogen dominant if I did it right. I don't want to make that decision on my own but would rather get that diagnosis from someone who knows for sure. Is that something you can help me with? I'd love to hear your thoughts on this. I have several symptoms which include hair thinning, breat tenderness, cold feet, decreased sex drive, dry eyes, weight gain around abdomen, fatigue, foggy thinking, headaches, hypoglycemia, insomnia, low magnesium, papitations. If you feel that progesterone cream might be an answer to my prayers, what dosage should I use and how often?? Thank you so much in advance for any help you can give me. I look forward to hearing from you soon!!

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Sep 12, 2012
Estrogen Dominance?
by: Wray

Hi there You certainly do have a lot of Oestrogen Dominance symptoms! Your P:E2 ratio is 74:1, we've found from Saliva Tests we run, that it's best if it's 600:1 and over. We do have a page on Hormone Testing you could look through. I normally recommend 100-200mg/day progesterone, but this is dependant on symptoms. The more severe they are the more is needed, so I feel you should start on the 200mg/day. It is trial and error. I'm taking a guess you are now in Peri-menopause, but you could look through our Menopause page too. We also have a page on Hair Loss, and someone has contributed this info here. too. Please look through our page on Breast Tenderness. Oestrogen lowers body temps, progesterone is thermogenic so raises them. Normal oral body temperature in adult men and women ranges between 33.2–38.2 °C (92–101 °F). Typical average temperatures are 37.0 °C (98.6 °F). In women it varies between the follicular and the luteal phase. During the follicular phase, i.e. from the first day of menstruation to ovulation, it ranges from 36.45 to 36.7 °C (97.6 to 98.1 °F). During the 12-14 day luteal phase, i.e. after ovulation to menstruation, temperature increases by 0.15 - 0.45 °C (0.2 - 0.9 °F) due to the increased metabolic rate caused by rapidly rising levels of progesterone. Temperature ranges between 36.7 - 37.3°C (98.1 - 99.2°F) during the luteal phase, but drops down to follicular levels within a few days of bleeding. Oestrogen causes dry eyes, in it's worst form it's called Sjogren's syndrome, see here, here, here and here. Continued below.

Sep 12, 2012
Estrogen Dominance? part 2
by: Wray

Hi there The weight around the abdomen is caused by excess testosterone, see here and here. If bound to SHBG (sex hormone binding globulin) testosterone becomes inactive, progesterone raises levels of SHBG, see here, so preventing the rise of free testosterone. SHBG drops if sugars are eaten, even those found in all grains, legumes, dairy and sweet starchy fruits and vegetables. Fructose, sucrose and glucose, reduce SHBG by 80, 50 and 40% respectively, see here. Thereby allowing testosterone to rise. It's best to avoid all the foods and sugars mentioned. I could give you more papers on all the other symptoms, but you'd probably get another symptom from all the reading! Take care Wray

Sep 13, 2012
Estrogen Dominance
by: Estrogen Dominance

Thank you Wray for the information and yes, I'm 46 and probably in peri-menopause. Appears my instincts are correct with regard to the Estrogen Dominance. If I understand correctly my ratio should be closer to 600 and I am at 74. ?? You mention that I should us 200 mg per day. Is it easy to figure out how much that is, i.e. teaspoon, etc. ? I'm also very curious about the palpitations (ectopic hearbeats) that I've experienced since my early 20's. Would some of that be related to the low progesterone or hormone imbalance? I know that high estrogen can also lower your magnesium level which plays a role in your heartbeat as well. Could I have been out of balance since that early age? How quickly will I notice some changes as I begin progesterone therapy? Is it possible that some of my hair thinning can be reversed. Sorry for all of the questions but you have been more helpful then my doctor already and it's wonderful to have some insight into how I've been feeling and so looking forward to feeling better.

Sep 14, 2012
Estrogen Dominance
by: Wray

Hi there Yes your instincts are correct. We have found if the ratio is 600:1 and over symptoms are relieved, it does vary of course. This is higher than that suggested by labs who do testing. And yes your ratio is 74:1. I'm so sorry, I din't give you our page on How to use progesterone cream, because it's generally for younger women. At the end of this page is a chart giving ml and tsp measurements. It is only for our cream, it would require too much space to do it for all brands! But if you can work out how many mg/ml in the cream you chose, you can still use this chart to help figure it out. I'm going to ask the webmaster to add the chart to the bottom of the P-M and menopause pages too. The palpitations could well be caused by the hormonal imbalance. The good thing is you've been checked for other possible causes and none were found. I'd be interested to hear if you start the progesterone whether it helps you. But please be aware of oestrogen dominance, symptoms can become worse. To overcome the stimulating affect progesterone has on oestrogen the only recourse is to increase the amount. Lowering it also helps, as the stimulation is no longer there, but it defeats the purpose. Although these comments are about asthma, you will see what I mean about using too little exacerbating existing symptoms, see here. It is possible to be out of balance from an early age, you might like to see the page on Menstruation which gives more details. It could be you lack vitamin D, most of us do, so please have a test done. It's so important for every cell to function normally, not least the hair. There are further nutrients you can take too, all listed on the page. Progesterone will help, but it's not the only thing needed. You could notice progesterone's affects immediately, if you use too little! But how long before you find relief is anyone's guess. Each individual responds differently, there are so many other factors influencing our well being, it's impossible to know which one. Take care Wray

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