Elevated Blood Pressure, can Progesterone help?

by Pauline
(Spain)

Two days ago I turned 51. I've been having hot flushes for about six months. The onset of menopause is an exciting time, having suffered for many many years with one ailment or another every month. Being period free is a new lease of life for me.

Recently my blood pressure readings are showing signs of raising to where the doctors want to start me on medication. I am healthy and fit, I eat well, don't smoke or drink and so on - I do all the right things.
I've been telling my doctors for years that I have estrogen dominance - they just ingnored me... It's only recently I have found all this information about the subject and am in the process of buying my first batch of progesterone cream.

My question is this - is there a possiblilty that when I start using the progesterone cream the balance could bring the blood pressure back to within a more normal range ?

My family history indicates to the doctors to put me immediately on medication. I don't want to start taking blood pressure drugs until I have tried a more natural approach. In fact, maybe the elder women in my family, who have died in their early 50's would have benefitted from progesterone - we'll never know about them but maybe, I can stop the trend!?

Comments for Elevated Blood Pressure, can Progesterone help?

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Nov 13, 2010
Elevated Blood Pressure, can Progesterone help?
by: Wray

Hi Pauline If the high BP is caused by vasoconstriction, progesterone can help as it's a vasodilator. Sharp declines have been observed in the early and late luteal phase of women when progesterone peaks, see here and here. If the high BP is caused by excess aldosterone it can help. The hormone aldosterone causes sodium and water retention, which increases blood volume and pressure. Progesterone inhibits aldosterone, by occupying the same receptor sites, see here and here. BP also increases if the renin-angiotensin system is activated, it's sometimes called the renin-angiotensin-aldosterone system. If blood volume drops the system kicks in. Renin is made by the kidneys, this stimulates the production of angiotensin, which is a potent vasoconstrictor, which increases BP. Angiotensin also stimulates the release of aldosterone, which of course causes sodium and water to be retained, so BP goes up. Essential hypertension accounts for 95% of all cases of hypertension, ie it's idiopathic or not known. Although a number of factors are known, obesity, insulin resistance, high alcohol intake, high salt intake, ageing, stress, low potassium and calcium intake, see here. They are even suggesting our genes are responsible! But one thing which is always overlooked, a lack of vitamin D causes the renin-angiotensin-aldosterone system to come into play. I believe this is the primary cause of high BP, which is increasing the world over. Due to the misguided advise of governments to avoid the sun, by covering up or using suncreens. I know you live in Spain, which is a 'sunny' country, but studies of people living on the equator have found a lack of vitamin D in the participants. Please have a test done, for more info please see the Vitamin D council website. Please look at these papers on the affect low vitamin D has on BP here, here, here and here. Finally a lack of vitamin D reduces the benefits of progesterone. Take care Wray

Feb 22, 2012
Please make Natpro more affordable
by: Anonymous

Since so many people need a higher dosage of progesterone .Its hard to decide between a tube of it or groceries in this economy. I know yours is less expensive than most available but still its expensive esp when u need to use high doses.
couldnt a higher dosage in one tube be made or make a larger tube for the same price??? ..I really would like to cont to use but i go through two tubes a month..( just wanted to see if someone in the near future is under development )
..
Thanks

Feb 24, 2012
Please make Natpro more affordable
by: Wray

Hi there I wish we could reduce the price, but we've kept it at the $23 for 3 tubes for 15 years now, absorbing the price increases in all the raw materials. Making a larger tube would entail a price increase, as the cost of the tube is nothing, compared to the cost of the ingredients. Maybe you have friends who use it, and you could share the cost of 20 tubes. That comes with a 30% discount. Take care Wray

Feb 24, 2012
price
by: Anonymous

23 dollars for 3 tubes you say ?because i have paid 50 dollars for 3 tubes with a one time discount ..you mean 23 dollars each then.well maybe its time for me to shop around then for a bigger tube :)
Thanks.

Feb 25, 2012
price
by: Wray

Hi there That was rather obtuse of me. I meant $23 each if you buy three tubes. There are companies selling bigger tubes, but you'll find they all contain about 480mg per ounce. Or 960mg per 2 oz. Some make 3oz containers which have 1260-1440 mg progesterone. Please be aware of this, the Natpro contains 1000mg/oz. You'll have to work out the cost of the active when you find one, don't go by the cost of the container. Take care Wray

Apr 19, 2012
High blood pressure
by: Angela

I have just started using progesterone cream and I am noticing an increase in my blood pressure. Is this normal? Will it go back to normal when I have leveled out. It has been about 3 days of use.


Apr 20, 2012
High blood pressure
by: Wray

Hi Angela I would have to know how much you are using, but it appears to be the usual 20-40mg/day. I've found too low an amount can cause adverse symptoms, leading to Oestrogen Dominance. Progesterone initially stimulates oestrogen, oestrogen causes water retention, which not only causes BP to rise, but weight gain. Progesterone is an excellent diuretic, it's not responsible for the water retention or high BP. In fact it's now used for Traumatic Brain Injury victims to reduce oedema. Plus if too little is used for too long it also causes fat increase which adds to the weight gain. Oestrogen stimulates fat cells to proliferate. If you are using a small amount, please increase it, I suggest 100-200mg/day dependant on symptoms. We do have more info on our page How to use progesterone cream. Take care Wray

Apr 20, 2012
Elevated Blood Pressure
by: Anonymous

I was using only 10mg pump at night. But when reading and finding out I needed to use more since Wed I have increased it to 2 pumps which is 20mg. That is when I notice the rise in blood pressure. So last night I did not use any and my blood pressure is better today. But the bodyaches were terrible. So I am wondering if I should contuine to use it to get my haromone to level out and everything will settle back to normal. I have had a hyst probably 10 yrs ago and have been using a harmone patch and just recently stop and trying something natural. My doctor told me to use the cream 100mg a day. Now I am not sure how that equals out to what I am using since it only tells me that the pump contains 10mg of progesterone a pump.

Apr 21, 2012
Elevated Blood Pressure
by: Wray

Hi Angela 10mg/day is far too little, I thought you couldn't be using much. 20mg/day is too little. Progesterone should be used a minimum of twice a day too, as levels drop after about 13 hrs. I recommend 100-200mg/day, more if symptoms are severe. So your doctor was right. If you want to use 100mg/day and your pump gives 10mg/pump, then you would have to pump it 10 times to get 100mg. 20 times if you want 200mg/day. The oestrogen you've stimulated would be causing the body aches, as it's an inflammatory hormone. I've relieved you've stopped the patch, I don't believe any woman needs HRT. Take care Wray

Nov 12, 2013
Does Progesterone Elevate Aldosterone Levels?
by: Ali

Hi. I was chasing info. on the connection between aldosterone and many things... and I happened to check on how progesterone affects aldo levels and several sites were claiming that progesterone raises aldosterone. In my case... I need it kept in check. I see at your site that you believe progesterone can help remedy high aldosterone. Can you help me understand this? Thank you. :0)

http://jcem.endojournals.org/content/91/10/3981.long


Nov 15, 2013
Does Progesterone Elevate Aldosterone Levels?
by: Wray

Hi there I don’t have the time to go into the details here. I have given papers to the queries above you could look at. And you might like to read this page here. Take care Wray

Nov 19, 2013
Lower BP naturally
by: Anonymous

Taurene and Copper work even better so does magnesium. They immediately drop top and bottom numbers ;)

Nov 19, 2013
Thank you.
by: Ali

Thanks very much Wray. That is a fabulous article full of good information. Blessings! Ali :0)

Jan 28, 2014
Progesteron gel and higher b/p
by: Anonymous

I started taking Progesteron gel 10mg. 25 days ago. I use 1/4 teaspoon at night, rub it on my upper chest. Instructions per my D.O.M. doctor. I noticed after almost 3 weeks of using it, my blood pressure went way up. I already take meds for high blood pressure, which was under control until a couple of weeks ago. This is the only thing I can think that caused this. It has been a struggle for two weeks with dizziness/lightheadedness and some nausea.

I stopped using the gel a week ago and just today 1/27/14, my blood pressure is normal and I feel a lot better. My D.O.M. doctor says this would not cause this, but I am very fearful of starting the gel again. I don't want this to happen a second time. By the way I am postmenopausal and have had a complete hysterectomy. Do you have any advice?

Feb 28, 2014
Elevated bp, heart palpitations & chest pain when using cream
by: Karli

Hi there,
I actually took a saliva test on the 20th day of my cycle (35day cycle) & it was reported back to me as clinically LOW (38.07). Looks like the normal range should be 127-446. The lab put "suggestions" and it says 500-3000 progesterone supplementation. Is that mg & is that every day for the 2 weeks before my period? I would basically have to use an entire bottle per day of my cream (20mg per 1/4tsp pump)!!
I was reading the threads above & noticed the woman had the same symptoms that I experienced- elevated bp. I naturally border on hypertension. I also experienced scary heart palpitations, growing chest pain & swelling of legs & feet that kicked in by the 2nd week of use. Scared me enough to stop cold turkey. I've been off for a week & I'm still experiencing slowly declining heart palpitations, swelling is going down & bp going down also. I'd love to know your thoughts, albeit I honestly don't think I can bring myself to slather on an entire bottle if that truly is the recommendation. Thx, Karli

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