Dr. Dalton vs Dr. Lee's dosing recs

by Shirley

Hi Wray.....I'm curious...Dr. Dalton's books started in the 60's....Dr. Lee didn't start getting info out until the 90's. Yet his dosing amounts are so much lower then what Dr. Dalton suggests. It would seem the doses should be even higher now with all the crap we're exposed to.

I'd be interested in your thoughts on this.


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Dr. Dalton vs Dr. Lee's dosing recs

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Jan 14, 2012
Dr. Dalton vs Dr. Lee's dosing recs
by: Wray

Hi Shirley You are so right! I was lucky enough to meet Dr Dalton several times before her death, such a lovely person, she gave her time freely to me as she knew I was trying to help other women. I've heard her speak, Dr Lee too, he was a wonderful man, excellent speaker. But they did disagree on the amount to use. I think the reason was Dr Lee found progesterone when many of his patients were entering menopause. Whereas Dr Dalton was principally helping much younger women. Women who were having major problems with miscarriages, pre-term births, pre-eclampsia, PND and post natal psychosis. She found much higher levels were needed to help these women, going as high as 2400mg/day for patients with post natal psychosis. She was adamant high amounts were needed, as studies using low amounts had not worked, and yet her dosing had. This is the reason I suggest high amounts too, following her advice. It's been an interesting journey for me, as so many write in complaining about progesterone. I then learn the amount used was the 'normal' 20mg/day, sometimes 40mg/day. But even this fails to raise progesterone above sub-luteal levels, see here. One persuasive argument for me, is if we make 20ng/ml per day during the luteal phase, and yet we have adverse symptoms, surely giving 20mg/day would be useless. And this is precisely what I've found, it is, in fact it's worse than not using it, as symptoms become worse. As for all the 'crap' we're exposed to, that too. Any stress, be it physical, mental or emotional, causes a cascade of inflammatory cytokines to be produced, causing oxidative stress. Plus exposure to toxins in food, air, water and skin care, which increases the free radical burden, also leads to oxidative stress, thence to many, if not all our modern diseases. To overcome this large amounts of antioxidants are needed, foremost being vitamin D, plus the antioxidant amino acids. And of course progesterone too. Interestingly, both progesterone and vitamin D regulate gene expression, have a positive fundamental effect on cell differentiation and growth, with anti-oxidative and autoimmune anti-inflammatory mechanisms. Both positively effect the nervous system by stimulating neurotrophic factors, quenching oxidative hyperactivity and regulating autoimmune responses. I will always encourage women to use far higher amounts of progesterone than the 'norm', but to me it's essential they take antioxidants too. Plus changing diet to one as organic as possible, using safe skin care, avoiding stress if possible too. Or at least learning to cope with it. Who doesn't have stress now, far, far too much! Take care Wray

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