Does progesterone definitely suppress ovulation?

I am almost driven demented with this. :). ........ my fertility doctor put me on clomid but after day 10 follicular tracking, she prescribed me Progesterone (Lutinus) 100mg x 2 daily as my lining was thinned out from the clomid.. She prescribed it every day of my cycle until I get pregnant and then I've to stop!

After researching it, all I'm reading is that its the common understanding that progesterone suppresses ov. I did ask a pharmacist about this and she rang the doctor to confirm if I was taking it the correct way. But the doctor says yes , to take it all cycle.

Has anyone got eany idea if it looks like the doctor made a mistake or does this somehow seem reasonable? I'd really hate to think I'm wasting my efforts each month. I'm wondering if I only take it after ov, will it still work on thickening my lining in that short time for implantation...

....I could not be more puzzled as to why she would prescribe it this way if its actually stoping me getting pregnant????

Thanks :/

Comments for Does progesterone definitely suppress ovulation?

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Jul 25, 2013
Does progesterone definitely suppers ovulation?
by: Hamideh

Hi...I am doing an artificial reproductive process (IVF) because of sever infertility problems, my husband and me have. Actually I don't know how effective the progesterone is on stimulating ovaries (the drug I took for this purpose was folitrophin alfa(Gonal-f) injection which provides FSH hormone to help ovaries with producing eggs) but during my treatment, since transferring embryo into my utters, I have been taking progesterone injection and supposed to go on until the pregnancy test. If a PBF, I will be again on progesterone. progesterone, a steroid hormone, is naturally produced inside female's body by the ovary in the luteal phase of the menstrual cycle and after pregnancy is also produced by placenta which helps with implantation of embryo as well as supporting it to be developed, generally it supports gestation. This is all I know my friend...
I wish you luck and success.

Jul 26, 2013
Does progesterone definitely suppress ovulation?
by: Wray

Hi there Well the ignorance surrounding progesterone sometimes leaves me stunned! For one thing it can stop ovulation if used before it. It works in the same way as any Contraceptive does, but with no adverse side affects. After all the progestins in the pill are merely synthetic versions of progesterone and they stop ovulation! Secondly progesterone inhibits mitosis, so it will never 'thicken' your lining! Only oestrogen can cause cells to proliferate. Even the Lutinus site says "In the presence of adequate estrogen, progesterone transforms a proliferative endometrium into a secretory endometrium." i.e. progesterone stops the proliferation. There's more info on our Menstruation page. Thirdly stopping progesterone once you know you're pregnant is a sure fire way of causing a miscarriage. I take it you are having problems falling pregnant? Please don't take any more clomid, see here, here and here. Please don't attempt to fall pregnant for a few months until it's cleared your system. Please have a vitamin D test done, often it's only a lack of this which prevents pregnancy. And that you are not 'Infertile'. See here and here. Please read our page on Pregnancy and this one here too to get an idea of how vital progesterone is and how to use it to best advantage. Incidentally a lack of vitamin D reduces the benefits of progesterone. Continued below

Jul 26, 2013
Does progesterone definitely suppress ovulation? Part 2
by: Wray

Hi there These are some papers on progesterone and IVF, see here, here, here, here, here, here, here, here, here, here, here, here, here, here, here, here and here. The first paper is actually one on diet. It seems a low carb diet and adequate protein is essential for a successful pregnancy, from the vitality of the egg to implantation and beyond. You might consider following the Paleo Diet, there's a link on our Nutrition page. Or try the Ketogenic Diet. This has higher fat to protein ratio than the Paleo, fat is essential for our hormones. I suggest you use the progesterone daily, for about 2-3 months, through any bleeding, to get your level high. Once you are ready to consider falling pregnant, then begin following your cycle. The pregnancy page explains how to use it for this. Continued below

Jul 26, 2013
Does progesterone definitely suppress ovulation? Part 3
by: Wray

Hi there Your Vitamin D level must be high too. For more info on vitamin D levels, test kits etc see the following websites, Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml or 175-250nmol/L, and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. I also suggest you take about 2000mg/day taurine, it's essential for a successful pregnancy and the growth of the foetus too. I've looked at the ingredients in the Lutinus and I'm not impressed. Suppositories would be far kinder to the vagina, these are often used for inadequate progesterone levels. Injections are often used too, but are painful and to my mind don't supply sufficient progesterone. They've also found that the creams are as effective as injections, see here. Take care Wray

Jul 26, 2013
I think only in excess of 100mg per day
by: davidgmills

I would like to know the answer to this question as well. I seem to remember Wray saying somewhere on this site that a woman can take 100mg per day during the follicular phase of her cycle and not affect ovulation. But I can not seem to find where I think I read that.

Maybe she will confirm this.

Jul 26, 2013
Re: progesterone suppressing ovulation?
by: Anonymous

Hi, you can check this out but I "think" that if you take progesterone before, you ovulate (ie from say day 6 when your period ends right up until day 28), that should prevent ovulation happening mid cycle. If you take it after, you ovulate then it helps to promote an environment in the womb that is very favourable to maintaining a pregnancy. Pro-gesterone means 'pro-gestation'. If you have too much estrogen and no progesterone to oppose it, you will continue to shed the lining of the womb (ie have a period)... However, obviously when pregnant, you make a lot of progesterone so that you don't, shed the lining and lose the pregnancy. Make sure you check these details out for yourself but that is my general understanding of how it works. Good luck.

Jul 29, 2013
I think only in excess of 100mg per day
by: Wray

Hi David I always appreciate your questions. You are right, I wouldn't trust 100mg/day to give contraceptive protection. The amount does depend on stress levels, and of course vitamin D too. Dr Dalton used 100mg or 400mg per day and found both effective, see here. She says "A daily dose of 100 mg (half a 200 mg suppository) or a 400 mg suppository are equally effective." I do have doubts about that, as I know one woman who used the lower amount only to fall pregnant. Stress is rarely taken into account, and stress drops progesterone levels, vitamin D too. So if a woman is using progesterone for contraceptive purposes she should be aware of this aspect, and increase the amount she's using substantially if she wants protection. And if her vitamin D is too low, the benefit of progesterone will be reduced. This will make the amount used ineffective. Take care Wray

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