Do I need progesterone?

by Cindy
(Abu Dhabi)

Hi Wray! I am a 34 year old female. I started using Zoloft 6 months ago as I was experiencing anxiety, 'foggy head' and depression.

Zoloft is an antidepressant. It has helped but in the Luteal Phase I am still experiencing 'foggy head' and slight depression. I am not sure if I should include progesterone in my treatment. I do have a fibroid and have read that progesterone can help with this. Really just need answers or advice as to what to do. I do feel tired/lethargic in the Luteal phase and during menstruation. I am taking a vitB complex and Omega 3 as well.

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Do I need progesterone?

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May 03, 2010
 Do I need progesterone?
by: Wray

Hi Cindy. Seems as if your oestrogen is too high in relation to your progesterone. Progesterone peaks during the luteal phase as you probably know, oestrogen also rises too. So if you don't make much progesterone during that phase you will feel tired and anxious too. It could be you're not ovulating each month, as it's only after ovulation that we make progesterone. Progesterone really does clear a 'foggy head', don't I know! As that was one of my symptoms too, plus what I called 'early onset senile dementia'! My short term memory was so bad I couldn't remember a thing. Progesterone does help fibroids, as it suppresses the high oestrogen stimulating their growth, please see here.

Progesterone also helps to raise serotonin levels so helping depression. It also activates the GABA receptor sites, GABA is one of our most calming neurotransmitters, a low level leads to anxiety and panic attacks. You don't need the Zoloft, what you do need are the nutrients from which our neurotransmitters are made. The amino acid tryptophan is the precursor to serotonin, the B vitamin inositol helps raise serotonin levels too. GABA is also an amino acid, but a difficult one to administer, too much and symptoms come back, I prefer to work with progesterone to raise GABA levels. We do have a web page on anxiety, please see here. If you do decide to use progesterone, I recommend a cream as the best delivery system, it can be used anywhere, and the dose adjusted to suit symptoms. For more info on how to use it please see here. And please read the web page on oestrogen dominance as this can occur and is very disconcerting if it does! Take care, Wray

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