Crinone question?

by Michelle
(USA)

Hi Wray,

Does Crinone 8% vaginal gel cause birth defects? It says on their website that it can, which confuses me as its progesterone?

Thanks for all your help!

Michelle

Comments for Crinone question?

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Apr 01, 2013
Crinone question?
by: Wray

Hi Michelle It's daft that statement, because if it was so every child born would have birth defects! We make up over 400ng/ml progesterone in the third trimester of pregnancy. If you're using it because of a possible miscarriage, or lack of progesterone in general, then the 8% will only give you 90mg progesterone. Amounts from 200-600mg/day are normally given if there are pregnancy problems related to progesterone. We do have a page on Pregnancy you could look through, and another here. Take care Wray

Apr 01, 2013
Re:Crinone ?
by: Michelle J.

Hi Wray,

Thanks for answering my question about the crinone. I felt it could not cause birth defects being progesterone but wanted reassurance from you. I miscarried again (4th)but I believe i've had more very early ones. I did talk with you before about my miscarriages and progesterone and you were so helpful. I am anxiously waiting for natpro to be back in stock so I can order it. I am pregnant again 5 weeks, and have told my Dr. I want to go back on the endometrin suppositories as crinone is horrible to use! She will only prescribe again 200mg daily suppositories so I plan on supplementing with your cream! I am insisting this time please God all going well, that she checks my progesterone levels as she has not done so yet... up to now at each check up my babies had no heartbeat by 6+ weeks. I am praying that this time is successful. I am also taking baby aspirin this time as I am willing to try anything. I am afraid I wont have the natpro soon enough...Thank you for your invaluable advice!!

Michelle J.

Apr 01, 2013
Crinone question?
by: RJ

Michelle,
A prayer will be said for you tonight and may God answer those prayers. Many blessings to you. RJ
Hello to you also Wray!

Apr 02, 2013
Re:Crinone ?
by: Wray

Hi Michelle I'm glad you've taken matters into your own hands. I'm so sorry about the stock out, the Easter weekend has not helped, as the fulfilment house closes. We are hoping for it to be in today, but it might take time for all systems to be fully operational again. If you use enough progesterone you shouldn't need the baby aspirin as progesterone prevents blood clotting etc, see here. Did I ask you to have a vitamin D test? If not please do so, as this is so vital for a successful pregnancy and the growth of the foetus, a lack also causes clots, see here, here, here and here. And miscarriages, see here, here and here. Please get your level up high, and when you have a chance watch the videos on vitamin D on our Pregnancy page. We also have another page on pregnancy here. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although recent research indicates it should be 10,000iu's per day, see here. Let me know how you get on. Take care Wray

Apr 03, 2013
crinone
by: Michelle J.

Thanks so much RJ, really appreciate that.
And thanks again Wray for your advice. I have my first OB appointment tomorrow and to be honest I don't feel very optimistic. The past 2 days I feel my pregnancy symptoms have decreased and my temp has dropped significantly. I think i've lost this baby too. I will know tomorrow. I feel sad but more so angry, i feel my Dr. did not do everything she could and should have done to help me. I don't blame her if I do miscarriage again but I feel it could have been prevented by more effort and input.. If it's bad news tomorrow I will not give up but I will definitely be finding a new Dr. I have been taking the vitamin D3,omega 3, vitamin C, folic acid will start taurine too. Is there anything else you can suggest Wray that may help. Thanks so much for your help.

Michelle J

Apr 04, 2013
Crinone question?
by: Wray

Hi RJ Many blessings to you too! Take care Wray

Apr 05, 2013
crinone
by: Wray

Hi Michelle I do hope you don't, but one good thing about all this, you have no difficulties falling pregnant, which so many do. Please have a vitamin D test done, this is so important. Once you know your level you will know how much you need to take to bring it up high. A lack of vitamin D causes miscarriages too, plus of course it affects the efficacy of progesterone. I'm pleased you're starting the taurine too, it's always overlooked for pregnant women, and yet one of the most important nutrients. The critical thing is to make sure you use the progesterone in the 12 hours prior to ovulation. If you are not getting the progesterone surge then, it will adversely affect how the embryo implants. It's vital for the success of the pregnancy if there is an early luteal phase rise of progesterone. The surge, or using supplemental progesterone prior to ovulation will ensure this, see here. Do let me know how you get on . Take care Wray

Apr 11, 2013
Crinone
by: Michele J.

Hi Wray,

wanted to update you. I went for my 1st ultrasound last week and she said she could see nothing. I was pretty sure by that stage from my symptoms I was going to miscarry anyway. I asked her to check my levels anyway, beta & progesterone and she agreed to do it. They had me come back and redo my bloodwork 3 days later and called me yesterday , said my beta was 70,000 and progesterone was 37.9!! She was surprised how high both levels were.. went back yesterday for ultrasound and there it was the most perfect little baby and heartbeat !! I am so happy I couldn't stop laughing :)had more b/w done and am waiting for results. I pray this little one is a keeper! Thanks so much Wray for your advice and everyone's prayers. Fingers crossed x Michelle

Apr 11, 2013
crinone
by: michelle j

Hi again Wray,
forgot to say I ordered your cream and am going to use it along with the endometrin, (she finally switched me back)not too sure how much to use? I am using 100mg endometrin 2 x day (200 total)

Thanks
Michelle

Apr 12, 2013
Crinone question?
by: RJ

Michelle, I was actually thinking of you today and thought I would write Wray to see what happened. Fantastic news!!! God does listen, but we must remember how many of our days is in just one of His days! I will say a prayer for a full term, healthy child! God Bless. RJ

And Wray may your sore tummy come around...I know that nausea feeling....yuck, yuck!

Apr 14, 2013
crinone
by: Wray

Hi Michelle I'm so delighted! Very pleased you insisted on having that check done, otherwise you would have gone away and felt very miserable for days, until it finally became apparent! 200mg/day is the minimum that seems to be used for recurrent miscarriages, up to 600mg/day. You'll find papers about miscarriage on our Pregnancy page if you wish to check them. I would feel happier if you were using 400mg/day, so you could use the cream more than once a day if you wished. And use the endometrin at night. Please don't forget to take the vitamin D, there are excellent videos at the end of the pregnancy page worth watching. And taurine too, so vital for the growth of the baby and for breastfeeding too. It's an essential amino acid for new borns, they can't convert it from cysteine. So need to get it in breast milk, if low they suffer, see here, here, here, here, here and here. Please let me know how you get on. Take care Wray

Apr 15, 2013
Crinone question?
by: Wray

Hi RJ Bless you! Yes it has, but I'm not eating much, the MCT oil really kills appetite! But as it gives you energy it doesn't leave you tired. Take care Wray

Apr 15, 2013
Crinone
by: Michelle J.

Thanks so much RJ, I really am grateful!

Wray, is 200mg cream approx. 1/2 teaspoon? If so, can I use all the 1/2 ts in the morning? Anywhere?
Also I am having some cramping which is a little concerning.
Thanks again for all your help!

Michelle J.

Apr 15, 2013
Crinone
by: Wray

Hi Michelle 200mg of progesterone is 6ml of cream, or just over 1 tsp. I would suggest you use some when you get up, some more maybe midday then again in the evening and the endometrin when you go to bed. Cramping can occur, if it does, rub the cream all over the area you can feel it. One of the roles of progesterone is to keep the uterus 'quiet'. Let me know how you get on. Take care Wray

May 09, 2013
Vitamin A?
by: Michelle J.

Hi Wray,

Is it safe to take Vitamin A during pregnancy? Most prenatal vitamins I've seen include 4000iu vitamin A. Is this a safe amount, if not what/how much do you recommend?

Thanks!
Michelle

May 12, 2013
Vitamin A?
by: Wray

Hi Michelle Vitamin A is needed by the body, but too much is not a good thing as it inhibits the uptake of vitamin D. Which is of far more importance to the growing foetus than vitamin A. This is from Dr Cannell's website......"Cod liver oil contains vitamin D. However, the Vitamin D Council recommends against taking cod liver oil because of the high amount of vitamin A there is in cod liver oil compared to vitamin D. Vitamin A is also a fat-soluble vitamin, so your body has a hard time getting rid of it and too much vitamin A can be harmful." Cod liver oil usually contains about 4000iu vitamin A. He also says "We think that humans most likely get enough vitamin A through diet and do not need to supplement with retinol. Too much vitamin A can be harmful to a developing baby, so if you’re pregnant don’t take vitamin A supplements. Don’t eat large amounts of liver or foods made from liver such as pate either, as these contain large amounts of vitamin A." See here. Take care Wray

May 13, 2013
Vitamin A?
by: Michelle J.

Hi Wray,
Yes I am still pregnant thank God! and using the endometrin and your natpro cream daily. I am also taking D3, omega 3,folic acid, vitamin C, and baby aspirin. After 4 miscarriages I believe the baby aspirin has helped me greatly as this is the pregnancy I've taken it and heard a heartbeat. I would like to take a good prenatal vitamin but they all contain vitamin A...
Do you think it would be enough to just continue on the vitamins I have listed above?

Thank you again for all your help!

Michelle J.

May 21, 2013
Vitamin A?
by: Wray

Hi Michelle The nutrients most important for pregnancy are vitamin D, at least 6000iu per day, please see the videos at the end of the Pregnancy page. And taurine, see here, here, here, here, here and here. Folic acid is good, but don't take too much as it can mask a B12 deficiency, about 400mcg/day is fine. I see no point in the aspirin, as progesterone, vitamin D and omega 3 all thin blood, you don't want it too thin! I would only add a B complex to the above list. Take care Wray

May 22, 2013
Vitamin A?
by: Michelle J.

Hi Wray,

Thanks for your feedback. I believe the baby aspirin was the help I needed as this is my 7th pregnancy (2 full term healthy babies so far)and the last few pregnancies I've taken all the above vitamins etc; including progesterone at ovulation onwards. This pregnancy is the only one I've taken the aspirin on so I really believe it helped me. So far so good and I will continue to take all the above throughout the pregnancy and hope for the best. Thanks for your advice and help so far it really is invaluable!

Best Wishes,
Michelle

May 29, 2013
Vitamin A?
by: Wray

Hi Michelle I do understand about your faith in the aspirin, above all it's important you feel happy and confident about the pregnancy. It'll make for a happy baby! They've found high cortisol levels in pregnant women result in the child suffering depression. Please let us know how you get on in the coming weeks. Take care Wray

Dec 31, 2014
Happy New year!
by: Michelle J.

Hi again Wray,

I haven't been on here in quite a while. I am hoping to try for one more baby, I am 43 now so a leap of faith I know! I did go on to have a perfectly healthy super smart I might add, little boy last fall and thank you again for all your help! I have a question about that may be silly but here goes....
I read somewhere recently that using progesterone for some time before conceiving increases your chance of having a baby girl, is there any truth to this. I know if anyone knows anything about this its you!!

Thank you!

Michelle J.

Jan 10, 2015
Happy New year!
by: Wray

Hi Michelle So delighted to hear you had the baby, after all the problems you'd had! Well I've not heard or read that, most odd! The sex of the baby is determined by the parent's genes, I fail to see how a hormone can affect the outcome of that. I can only imagine it was someone who found she only had girls, and put it down to the progesterone she'd used, and not thought about the role genes play. Do let me know the outcome of the birth, but it still won't prove the 'theory' one way or the other! And Happy New Year to you too! Take care Wray

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