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Coming off of Dhea and using progesterone

by Melissa
(North Carolina)

Hey there Wray! Thanks so much for sharing your story... Very inspirational! I pray the Lord blesses you for all the good work you are doing here and in helping others!

I have a question... I was on DHEA 10mg 2-3 times a day for chronic fatigue for 5-6 years. This helped initially but after awhile I didn't notice much energy from the DHEA. I started having these weird fainting sensations so I got my levels checked and my estrogen and testosterone were sky high and my progesterone was very low. I started on your Natpro cream right away and started to feel way worse... weird numbness and spaciness for about 2 months. I have continued on the cream about 1/8 tsp once a day and these symptoms are gone but I still have the fatigue and weight gain.

I gained about 15 pounds since coming off DHEA... I was 135lb and now am 150lb. I eat very healthy and try to exercise but I still can't seem to get the weight off. I suspect I might have low thyroid function even though my tests came back normal... I am taking a natural supplement for that. I know that excess estrogen can cause low thyroid as well.

My question is this... Should I continue on the Natpro cream if my saliva levels come back high even though I am having symptoms?

And what is your opinion about taking DIM to get rid of excess estrogen?

Thanks so much!

Comments for
Coming off of Dhea and using progesterone

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Sep 13, 2009
Coming off of Dhea and using progesterone
by: Wray

Hi Melissa. Thanks for the kind words! I'm very relieved you're not on the DHEA any more, it raises androgens, oestrogens and prolactin, it causes cysts and can cause cancer. Please see this paper:

"Also, DHEA may have a dark side. By facilitating internal production of testosterone and estrogen, supplemental DHEA could accelerate the growth of undetected prostate or breast tumors. Studies have shown higher levels of DHEA - and estrogens made from it - in people with breast cancer and endometrial cancer".

And this:

"Therefore, this study suggests that the ovarian cystic condition developed after DHEA treatment in rats, is associated with higher levels of circulating androgens, estradiol, and prolactin."

So it doesn't surprise me your oestrogen and testosterone were sky high and progesterone was very low! Both these hormones, plus prolactin, suppress progesterone. The reason you had those weird symptoms when starting the progesterone was the huge excess oestrogen you have! Please see this web page, it explains why.

The weight gain is due to the excess oestrogen you now have, the progesterone will help balance this, but you need far more than the 1/8th tsp, this is only giving you ±20mg/day. You would need about 200mg/day to reduce the high level oestrogen, testosterone and prolactin you have. It should be used at least twice daily too, to keep levels up. Tests only show how much of any one hormone is circulating, so even if your progesterone is high, it could be the ratio between oestrogen and progesterone is skewed, hence the continuance of symptoms.

Excess oestrogen also causes insulin resistance which could explain your weight gain, please see this web page.

The amino acid tyrosine suppresses prolactin too, it might be an idea to take some, about 1000-2000mg/day. Tyrosine is essential for thyroid function too, you probably have little due to the prolactin levels. DIM is excellent, safe and effective at reducing oestrogen levels, a good idea to take it. Take care, Wray.

Dec 08, 2009
Dhea and progesterone
by: Anonymous

I started with bio-dentical harmones and DHEA. My tests came out sky high too and progesterone low so I cut back on estrogens and then quit the DHEA and and Testosterone. I was growing facial hair and have been losing my hair ever since.

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