Can Progesterone cause pelvic organ prolapse?
I am 35 and have never had children but experienced pelvic organ prolapse last month. It happened about 6 weeks after I began using progesterone cream. The timing seems very suspicious to me.
Is it possible for there to be a connection?
On a support forum for prolapse, many others have noticed that the prolapse is worse at the times of the month when progesterone is higher and better when it is lower.
I have read that progesterone can relax or inhibit tone and 'contractibility' of tissues... but it seemed based in relation to pregnancy - when the body can be making more than 200mg/day (or 300mg/day near the end). I was taking 25mg/day.
It would be nice to know how much/little progesterone can effect tone and if, indeed, that is what causes the fluctuations of POP throughout the cycle.
Do you have any wisdom or opinion about this?
thanks so much