bioavailable diindolymethane

Hi Wray, I forgot to ask you if you have any experience or knowledge of DIM? I have also started to use that as well to assist with control of the excess estrogen. I would love to hear your thoughts!

Jayne

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Mar 17, 2013
bioavailable diindolymethane
by: Wray

Hi Jayne DIM is regarded as an anti-oestrogen. Oestrogen is broken down into 2 principle metabolites, 2-hydroxyestrone (2-OHE1) and 16-alpha hydroxyestrone (16alpha-OHE1). 16alpha-OHE1 is regarded as a potent oestrogen, whereas 2-OHE1 is a weaker oestrogen. In some studies DIM (3,3'-Diindolylmethane) increased levels of 2-OHE1, by doing so it also increases the ratio of 2-OHE1:16alpha-OHE1. This increased ratio is associated with a lower risk for breast cancer in some studies, not in others. It appears to have a positive affect on pancreatic, thyroid, prostate and gastric cancers too, and leukaemia. The precursor to DIM is Indole 3 Carbinol (I3C) which also has antioxidant and anti-cancer properties. These are a selection of papers here, here, here, here, here, here, here, here, here, here, here, here and here Some women have found it of benefit, others react to it and stop, you'll have to see how you get on. Take care Wray

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