I am 39 and have been diagnosed with estrogen dominance. My doctor prescribed 25mg oral progesterone on days 5-12 and 50mg oral progesterone on days 13-26. I have been halfway consistent with the dosages. I have started and stopped a couple of times in the last month because the effects have been awful! I've had insomnia, anxiety, depression, weight gain, flushing, heart palpitations. I don't know if this is normal for a couple of weeks or if this is as Reiss states due to candida. I have also changed doctors and the new doctor wants me on a higher dosage-150mg on days 15-28 and 50 mg on days 1-14. I am on day 24 of my cycle and at first, the 150mg gave me excellent sleep for about 4 nights. for the past two, i've been very anxious again and depressed and my belly HURTS as well. I'm scared to continue on with this stuff. I feel so alone and my family is worried. I've barely slept in a month. Any help, please. I'm very desperate.