Advise Me if I'm on the Right Track...

by Jeannette
(Toronto)

Hi Wray. I've been on Natural Progesterone for 5 months, Natpro for 3 of those. I was applying about 1 - 1 1/2 tsps daily yet the symptoms of Estrogen Dominance still persisted. The last 3 months I never took a break from it.(I am 52yrs old and still having my period.) So, after my last period I thought to defeat the estrogen once and for all and upped my dosage to about 3tsp/day, morning and night. Well, the estrogen is fighting back hard! I'm considering upping my dose to 4tsps for the next while. I am on 10,000 vit D/day and Iodine. Is increasing the Natpro the answer or should I tough it out my maintaining a stable amount? I'm sure by the end of menopause,I'll be stark, raving mad! Thank you.

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May 22, 2013
Advise Me if I'm on the Right Track...
by: Wray

Hi Jeanette Before you increase the progesterone, please have a vitamin D test done. Canada has some of the lowest levels found anywhere, see here, here, here, here and here. It's essential to get your vitamin D up high. You are taking a good dose, but it could be you need to take a higher one to get it up quickly. Once high it should begin to help and hopefully you'll find you won't need more progesterone. There are some women who do find they need very high amounts to help, see here, here and here. But cost is always factor I'm so aware of, and anything to keep it down is obviously the way to go. Please have that vitamin D test. For more info on vitamin D levels, test kits etc see the following websites, Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml or 175-250nmol/L, and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. We do have two pages you could look through, one on Peri-menopause which you're going through now, and one on Menopause which is approaching soon. Take care Wray

May 23, 2013
Continued....
by: Jeannette

Thank you Wray. The day I wrote that, things went from uncomfortable to horrifying. I started bleeding uncontrollably and that night, passed a blood clot the size of an eggplant. No exaggeration. I've been lightly but steadily bleeding since...and if I stood in front of the mirror, I could probably watch myself gain weight. I thought the opposite would happen, seeing as what I assume to be a fibroid had just dislodged. Anyway, I'm uncomfortable, to say the least. I have a ringing in my ears and am dizzy, but I assume that is an iron deficiency so am working on that. Thoughts? Again, I sincerely appreciate your time.

May 29, 2013
Continued....
by: Wray

Hi Jeanette The heavy bleeding and clots although horrifying is a good thing. It is cleaning out your lining which was obviously very thick with old clotted blood. Please consider taking at least 2000mg/day NAC (N-acetyl cysteine), 2000mg/day taurine, vitamin D which you are taking, and 1000mg/day bioflavonoids. There's more info on all the above and what they will do to help with continual bleeding on our Menstruation page. Dizziness is often caused by excess water in the ears, this can be the result of excess oestrogen which causes water retention. Increasing the progesterone as you did would initially stimulate oestrogen, but it should pass quickly. Apologies about the late reply but I have so much on my plate right now. Take care Wray

May 30, 2013
Continued...
by: Jeannette

Thank you Wray. It has been 2 weeks since my desperate plea to you. Since then, my life is completely changed. Thank you and your site for helping me keep the faith and carry on when I thought I was going to explode. Everything is better now. For all your followers who are suffering beyond description, I encourage them to keep on going. For 40 years I have suffered excruciating symptoms of oestrogen dominance....and now, my breasts are normal, my mood relaxed, my weight back on track, restful sleep, complexion cleared. Who knew that after using the cream for 6 months, this could happen in a matter of days?!! My fear is keeping the dose balanced so I don't crash.
Quick Question: My mom is in her 80's with rheumatoid arthritis. She's currently having a flare-up. Since PG is such a remarkable diuretic, would their be any harm that you know of in me giving her a tube to try? No rush to answer...if you have an answer to that. God bless.

Jun 01, 2013
Continued...
by: Wray

Hi Jeanette Bless you for persevering! And for using such a high amount too, the 3tsp amounts to 500mg/day progesterone. I can't believe you've suffered so long, and no one to give you advice about it, I find that so saddening. It's a shocking indictment of our society that women's problems are swept under the carpet. You must have been only 12 when it all started, far too young too cope with it, still a child. As the 500mg/day seems to have done the trick, please stick to it for a few weeks, cost allowing, before thinking of reducing it. I wish it were possible for all women to use very high amounts, it does work. And please don't forget to have that vitamin D test done. With regard to your mother, progesterone can help, it’s always low in RA. Interestingly far greater numbers of women have inflammatory/autoimmune diseases compared to men. RA is regarded as a TH1 immune response-driven disease, as a higher level of Th1 is found in RA patients. Th1 induces inflammatory cytokines, Th2 induces anti-inflammatory cytokines. Studies have found that induction of Th2 cytokines can reduce inflammation. Progesterone causes a shift from Th1 to Th2 immune response, increasing the anti-inflammatory cytokines IL-4 and IL-10. On the other hand oestrogen is an excitatory hormone and enhances the immune response, causing inflammation. Moreover, oestrogen stimulates the production of matrix metalloproteinases (MMP’s) which are enzymes that degrade protein and cause inflammation. If you had a chance to read that page on menstruation, you'll know that excess MMPs are responsible for continual heavy bleeding. Excess MMP’s are found in RA too. Excess oestrogen is also found in RA, see here, here, here, here, here, here, here and here. Continued below

Jun 01, 2013
Continued part 2
by: Wray

Hi Jeanette Please ask her to have a vitamin D test done, if she also lives in Canada she will have a low level. All the so called autoimmune diseases have low levels of vitamin D, including RA. Vitamin D also induces the Th2 anti-inflammatory response, see here, here, here, here, here, here, here and here. Please get her to have a test and to begin taking vitamin D, and to use the progesterone too. Both Progesterone and Vitamin D work synergistically. We do have a page on Inflammation you could look through too. Please let me know how she gets on. Take care Wray


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