27 and currently experiencing my 4th miscarriage

by Sarah
(Australia)

I am currently experiencing my fourth early miscarriage in two years. All pregnancies stopped developing around 4 weeks. The only thing that has some up in testing is a mild anti-phospholipid syndrome, but my specialist says this should not affect a pregnancy until after 8-10 weeks and mine have never progressed that far.

I fall pregnant very easily, but cannot keep them. I have regular periods but they are heavy and clotted. I also get bad fluid retention, have permanent dark circles under my eyes and tend to be quite moody. Previously I have been told that my progesterone levels were fine. Do you think it could be worth testing again?

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Jan 23, 2011
27 and currently experiencing my 4th miscarriage
by: Wray

Hi Sarah APS is implicated in miscarriages, see here. It seems a lack of vitamin D could be a causative factor too, see here. I don't agree with their <15ng/ml as the cut off point for a deficiency, new research suggests 30ng/ml, with a normal level being 50 to 100ng/ml. For more info on vitamin D see the Vitamin D council website. Please consider having a vitamin D test done, as levels are low in Australia, see here, due to the anti-sun campaign. Elevated levels of NK cells and TNF-alpha are found in APS, although the reason seems to elude researchers. It could well be a lack of progesterone as this suppresses TNF-a and the inflammatory cytokines, plus it increases the anti-inflammatory cytokines, see here, here, here and here. We're often told progesterone levels are fine, but the ratio of progesterone to oestrogen is never taken into account. So if you have a test done, please look at the ratios. From Saliva Tests we run regularly, we've found a ratio of 600:1 and over is needed. A lack of progesterone is implicated in miscarriages too. We do have a page on Pregnancy, please take a look at it. Before you consider using it please see our page on Oestrogen Dominance. This can occur and is disconcerting if it does. Take care Wray

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